김희진 교수

Background Research on whether wearable devices and app-based interventions can effectively prevent metabolic syndrome (MetS) by increasing physical activity (PA) among middle-aged people living in the rural areas of South Korea remains insufficient. Objective The aim of this study was to determine whether mobile and wearable device interventions can improve health indicators, including PA, in MetS risk groups in rural South Korea. Methods In this clinical trial, performed from December 2019 to

The aim of this study was to introduce the implemented MEDBIZ platform based on the internet of medical things (IoMT) supporting real-time digital health services for precision medicine. In addition, we demonstrated four empirical studies of the digital health ecosystem that could provide real-time healthcare services based on IoMT using real-world data from in-hospital and out-hospital patients. Implemented MEDBIZ platform based on the IoMT devices and big data to provide digital healthcare ser

A molar-incisor malformation (MIM) is a recently reported dental anomaly that causes premature loss of the first molar with severe dentoalveolar infection. However, there has been no research on the pathogenesis yet. The aim of this study was to report the clinical process of MIMs and investigate the pathogenesis by conducting a microbiome analysis. An eight-year-old girl was diagnosed with MIM and after two years, four permanent first molars were sequentially extracted due to severe dentoalveol

A unified diagnostic criterion has yet to be established for sarcopenia. Therefore, we analyzed the reliability and validity of sarcopenia diagnosis using bioelectrical impedance analysis (BIA) compared with the gold standard, dual-energy X-ray absorptiometry (DEXA), and evaluated the predictive accuracy of BIA for diagnosis. The clinical trial, involving a total of 239 participants, was conducted between December 2018 and September 2019 on healthy volunteers without significant medical historie

In this study, to understand whether D-allulose,an ultra-low calorie sweetener, was available in soy yogurtfermentation, we isolated Leuconostoc mesenteroides andLactobacillus plantarum from kimchi and fermented insoymilk at various contents of D-allulose and sucrose. Thelactic acid bacteria counts in soy yogurt had the highestrange of 9.23–9.49 log CFU/g at 24 h fermentation andthen decreased. At 48 h fermentation, the pH showed 4.31and 4.52 in the samples containing 75% and 100% D-alluloseas s

배 경:증식세포인자인 IL-6와 경화증 성장인자인 TGF-β의 요 분비 측정이 질환의 활성도 및 예후 판단에 유용함이 제시되고 있다. 따라서 IgA 신증 환자들에서 IL-6와 TGF-β의 요중 분비를 측정하고 AII 수용체 차단제(ARB)의 치료 효과를 조사하였다. 방 법:IgA 신증 환자들(n=10)을 대상으로 ARB 치료 전과 2개월간의 치료 후에 각각 오전 10시경의 소변을 채취하여 저장한 후 enzyme-linked immunosorbent assay법을 이용하여 측정하였고 요중 크레아티닌 농도로 보정하였다. 결 과:ARB 치료 전 IgA 신증 환자들의 요중 IL-6와 TGF-β의 분비량은 다른 사구체질환군과 같이 대조군에 비해 유의하게 높았다. IgA 신증 환자들의 요중 IL-6와 TGF-β분비량 사이에는 양의 상관이 관찰되었다(p<0.01). 또한 요중 IL-6 분비와 단백뇨량은 통계학적으로 유의한 양의 상관을 나타내었다(p<0.05). 요중 IL-6 및 TGF-β 분비와

The rate of salt and sugar into pickled cabbages was determined, and physicochemical characteristics, such as sensory, texture, and pH, of vinegar pickled cabbages during storage were examined at different storage temperatures and vinegar concentrations. The rate of salt and sugar penetration was faster in smaller size and on leaves rather than the stem of cabbage. Also, higher salt and sugar concentration and higher storage temperatures led to increase in salt and sugar permeation rate. As a re

<sec> <title>UNSTRUCTURED</title> The aim of this study is to introduce the implemented big data platform (MEDBIZ) based on the internet of medical things (IoMT) supporting digital healthcare services and to discuss about application cases of this platform. Implemented MEDBIZ platform based on the IoMT devices and big data to provide digital healthcare services to the enterprise and users. The big data platform is consisting of four main components: IoMT, Core, Analytics, and Services. IoMT comp

Goodpasture 증후군은 우리나라에서는 극히 드문 질환으로 급성신부전과 폐출혈이 있으면서 항 사구체 기저막 항체가 증명될 경우 확진되며 혈액투석, 혈장교환술, 면역흡착법 등의 방법을 통해 항 사구체 기저막 항체의 역가를 감소시키고 면역억제제를 투여하여 항체 형성을 억제할 경우 임상 증상의 빠른 호전을 기대해 볼 수 있다. 저자들은 이전에 보고된 경우가 대량 폐출혈을 동반했던 것과 다르게 미만성 폐출혈 양상이었으며 신질환에 있어서는 좋지 않은 예후를 보였던 Goodpasture 증후군 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

In order to collect information on local distribution of conductivity and permittivity underneath a scan probe, we developed a multi-frequency trans-admittance scanner (TAS). Applying a sinusoidal voltage with variable frequency on a chosen distal part of a human body, we measure exit currents from 320 grounded electrodes placed on a chosen surface of the subject. The electrodes are packaged inside a small and light scan probe. The system includes one voltage source and 17 digital ammeters. Fro

<sec> <title>BACKGROUND</title> Research on whether wearable devices and app-based interventions can effectively prevent metabolic syndrome (MetS) by increasing physical activity (PA) among middle-aged people living in the rural areas of South Korea remains insufficient. </sec> <sec> <title>OBJECTIVE</title> The aim of this study was to determine whether mobile and wearable device interventions can improve health indicators, including PA, in MetS risk groups in rural South Korea. </sec> <sec> <t

Periogen은 실시간 PCR 방법을 이용한 우식활성 검사법으로, 치아우식 유발균에 대한 정량적인 분석을 통해 개개인의 치아우식 위험도를 평가한다. 이 연구는 소아에서 Periogen과 치아우식 경험 지수(dmft, dmft indices)와의 상관성을 평가하고, 기존의 치아우식위험 검사법인 Cariview, 치아우식 평가 도구(Caries Assessment Tool)와 비교할 목적으로 시행되었다. 만 6세 미만 83명의 소아를 대상으로 실험이 진행되었다. 시진을 통해 치아우식 경험 지수(dmft, dmft indices)가 기록되었으며, 간단한 설문 조사를 통해 CAT 평가 시행되었다. Periogen, Cariview는 제조사의 지시에 따라 치아우식 위험도 평가 시행되었다. 그 결과 Periogen, Cariview 그리고 CAT는 dmfts index와 상관계수가 각각 0.38, 0.56, 0.66을 보여 모두 중등도의 상관관계를 보였다(p < 0.01). Periogen,