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최희정 교수

Hee-Jung Choi

이화여자대학교 의학과 · 의학

연구실 소개

최희정 교수의 연구실은 면역학적 기전과 기생충 감염의 상호작용을 중심으로 한 전염병학 및 숙주-병원체 상호작용을 연구합니다. 특히 HIV-1 감염에서 IL-18이 IFN-γ를 통해 바이러스 억제 기전을 발휘하는 메커니즘과, 두창충(Diphyllobothrium latum)과 같은 기생충 감염의 임상 및 역학적 특성에 대한 분석을 수행하고 있습니다. 또한 해산물 생물의 면역 반응과 병원성 기생충의 상호작용을 유세세포 분석을 통해 규명하고 있습니다. 이와 더불어, 병원성 감염 예방을 위한 항생제 사용 전략의 최적화를 목표로 한 임상 연구도 진행 중입니다.

면역반응기생충 감염HIV-1해산물 면역학항생제 사용 전략

연구 현황

논문 수
275
총 인용 수
3,404
최근 5년 논문
46
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
46총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
387총합
20222023202420252026

주요 논문

15
1
논문|인용수 55·2016
Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity
C.-J. Kim, Won Suk Choi, Yu Mi Jung, S. Kiem, Hee Yun Seol, Heungjeong Woo, Young Hwa Choi, Jun Seong Son, K.-H. Kim, Kim Ys, Sung‐Min Kim, Seong Ho Park
SJR Q1Clinical Microbiology and InfectionOA
Infectious DiseasesMedicine
2
논문|인용수 42·2001
Interleukin‐18 Inhibits Human Immunodeficiency Virus Type 1 Production in Peripheral Blood Mononuclear Cells
Hee Jung Choi, Charles A. Dinarello, Leland Shapiro
SJR Q1The Journal of Infectious DiseasesOA

Interleukin (IL)-18 is an interferon (IFN)-gamma-inducing factor and contributes to the Th1 immune response. IL-18 added after infection of peripheral blood mononuclear cells (PBMC) with monocyte-tropic human immunodeficiency virus type 1 (HIV-1) inhibited p24 antigen production by a maximum of 72%. IFN-gamma levels in these cultures were increased, and a significant inverse relationship between HIV-1 production and IFN-gamma levels was observed. A neutralizing anti-IFN-gamma antibody reversed t

VirologyImmunology and Microbiology
3
논문|인용수 40·2016
Five-year decreased incidence of surgical site infections following gastrectomy and prosthetic joint replacement surgery through active surveillance by the Korean Nosocomial Infection Surveillance System
Hee Jung Choi, Lira Adiyani, Jae Kyu Sung, Jun Yong Choi, Hong Bin Kim, Young Keun Kim, Yee Gyung Kwak, Heon Yoo, Sang‐Oh Lee, Su Ha Han, S.R. Kim, Tae Hyong Kim
SJR Q1Journal of Hospital InfectionOA
SurgeryMedicine
4
논문|인용수 31·2007
Molecular characterization of an acute hepatitis A outbreak among healthcare workers at a Korean hospital
Jong Hyeok Park, J.B. Lee, Seo Young Jeong, Summi Lee, Minsung Lee, Hee Jung Choi
SJR Q1Journal of Hospital Infection
HepatologyMedicine
5
논문|인용수 28·2009
Flow cytometric analysis of Salmonella enterica serotype Typhimurium inactivated with supercritical carbon dioxide
Hee Taek Kim, Hee Jung Choi, Kyoung Heon Kim, Kyoung Heon Kim
SJR Q3Journal of Microbiological Methods
BiotechnologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 21·2012
Four Human Cases of Diphyllobothrium latum Infection
Hee Jung Choi, Junghye Lee, Hyun-Jong Yang
Korean Journal of ParasitologyOA

Diphyllobothrium latum infections in 4 young Korean men detected from 2008 to 2012 are presented. Three were diagnosed based on spontaneously discharged strobila of the adult worm in their feces, and 1 case was diagnosed by finding the worm at colonoscopy examination in a local clinic. The morphologic characteristics of the gravid proglottid and eggs were consistent with D. latum. All patients were treated with praziquantel 15 mg/kg, and follow-up stool examinations were done at 2 months after t

EcologyEnvironmental Science
7
논문|인용수 21·2020
Risk factors of delayed isolation of patients with pulmonary tuberculosis
C.-J. Kim, Yoonsoo Kim, Ji Yun Bae, A. Kim, Jinhyuk Kim, Hee Jung Son, Hee Jung Choi
SJR Q1Clinical Microbiology and InfectionOA
Infectious DiseasesMedicine
8
논문|인용수 12·2016
Of Soldiers and Citizens: Shallow Marketisation, Military Service and Citizenship in Neo-Liberal South Korea
Hee Jung Choi, Nora Hui‐Jung Kim
SJR Q1Journal of Contemporary Asia

The Nationality Law and the Military Service Law in South Korea were changed in 2004 and 2005 respectively to enable tighter control over the conscription of male citizens. This movement stands in contrast to other industrialised countries, where conscription has been replaced by professional and marketised military services. This article explains the Korean exception as “shallow marketisation,” one particular way the connection between citizenship and military service is being reconfigured in t

Political Science and International RelationsSocial Sciences
9
논문|인용수 12·2012
Four Human Cases of Diphyllobothrium latum Infection
최희정, Junghye Lee, 양현종

Diphyllobothrium latum infections in 4 young Korean men detected from 2008 to 2012 are presented. Three were diagnosed based on spontaneously discharged strobila of the adult worm in their feces, and 1 case was diagnosed by finding the worm at colonoscopy examination in a local clinic. The morphologic characteristics of the gravid proglottid and eggs were consistent with D. latum. All patients were treated with praziquantel 15 mg/kg, and follow-up stool examinations were done at 2 months after t

10
논문|인용수 11·2001
Public Health Nurses' Decision Making Models and Their Knowledge Structure
Hee Jung Choi
Daehan ganho haghoeji
Leadership and ManagementNursing
11
논문|인용수 10·2011
Non-specific Defensive Factors of the Pacific OysterCrassostrea gigasagainst Infection withMarteilioides chungmuensis: A Flow-Cytometric Study
Hee Jung Choi, Jee Youn Hwang, Dong Lim Choi, Min Do Huh, Young Baek Hur, Nam‐Sil Lee, Jung Soo Seo, Mun Gyeong Kwon, Hye-Sung Choi, Myoung Ae Park
Korean Journal of ParasitologyOA

In order to assess changes in the activity of immunecompetency present in Crassostrea gigas infected with Marteilioides chungmuensis (Protozoa), the total hemocyte counts (THC), hemocyte populations, hemocyte viability, and phagocytosis rate were measured in oysters using flow cytometry. THC were increased significantly in oysters infected with M. chungmuensis relative to the healthy appearing oysters (HAO) (P<0.05). Among the total hemocyte composition, granulocyte levels were significantly inc

Global and Planetary ChangeEnvironmental Science
12
논문|인용수 10·2018
Impact of a change in duration of prophylactic antibiotics on infectious complications after radical cystectomy with a neobladder
Chung-Jong Kim, Kwang Hyun Kim, Wan Song, Dong Hyeon Lee, Hee Jung Choi
SJR Q3MedicineOA

A profound number of prophylactic antibiotics are used after radical cystectomy with an ileal orthotopic neobladder (RCIONB) despite a negative effect of infection control. We investigated the impact of short-term prophylactic antibiotic use on infectious complications after RCIONB.We retrospectively reviewed data from 287 patients who underwent RCIONB for bladder cancer between 2012 and 2016 at a tertiary hospital. The patients were divided into 2 groups according to the pattern of prophylactic

SurgeryMedicine
13
논문|인용수 9·2018
Emphysematous endocarditis caused by AmpC beta-lactamase-producing Escherichia coli
Chung-Jong Kim, Jeong‐Eun Yi, Yookyung Kim, Hee Jung Choi
SJR Q3MedicineOA

Emphysematous endocarditis is an uncommon complication of E coli bacteremia. Certain phylogenetic groups may be associated with development of E coli endocarditis.

EpidemiologyMedicine
14
논문|인용수 6·2003
The role of ascorbic acid on the redox status and the concentration of malondialdehyde in streptozotocin-lnduced diabetic Rats
Hee Jung Choi, Hyun Dong Je, Ji Hoon Jeong, Young Sil Min, Tae Sik Choi, Joon Hong Park, Chang Yell Shin, Uy Dong Sohn
SJR Q1Archives of Pharmacal Research
Nutrition and DieteticsNursing
15
논문|인용수 5·2021
Cumulative Impact Assessment for Marine Spatial Planning: A Case Study of the Gyeonggi Bay in South Korea
Hee Jung Choi, Sung‐Jin Cho, Taekeon Hwang, Jungho Nam, Chul‐sue Hwang
Journal of Coastal Research

Choi, H.-J.; Cho, S.-J.; Hwang, T.; Nam, J., and Hwang C.S., 2021. Cumulative impact assessment for marine spatial planning: A case study of the Gyeonggi Bay in South Korea. In: Lee, J.L.; Suh, K.-S.; Lee, B.; Shin, S., and Lee, J. (eds.), Crisis and Integrated Management for Coastal and Marine Safety. Journal of Coastal Research, Special Issue No. 114, pp. 360–364. Coconut Creek (Florida), ISSN 0749-0208. Cumulative impact assessment (CIA) techniques for marine spatial planning (MSP) exist in E

Management, Monitoring, Policy and LawEnvironmental Science

대표 연구 분야

Infectious DiseasesSurgeryEpidemiologySociology and Political ScienceMolecular MedicineMolecular Biology

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