최홍조 교수

한국은 OECD국가 중 결핵 발생률, 사망률, 다제내성결핵발생률이 1위인 만큼 결핵으로 인한 질병부담이 상당한 국가이다. 하지만, 결핵의 사회적 결정요인을 탐구하기 위한 관심은 부족한 실정이다. 본 연구는 첫째, 2000년 이후 국제적으로 결핵의 사회적 결정요인에 대한 실증 연구들의 현황을파악하고 그 성과를 확인하고자 한다. 둘째, 1990년대 이후 한국의 결핵 연구 동향을 살펴보고, 사회적 결정요인과 관련한 국제적 연구 흐름에 비추어 어떠한 유사점과 차이점이 있는지 확인하고자 한다. 마지막으로 이러한 검토 결과에 기초하여, 근거기반 결핵 정책 개발을 위해 한국의 결핵연구가더욱 관심을 기울여야 할 방향을 제시하고자 한다. 본 연구에서는 결핵의 기여인자에 대한 기존 문헌의 유형표를 수정하여 사용한다. 수정된 유형표에따라 체계적 문헌고찰을 진행하며, 검색어로 제목에 ‘tuberculosis’, 주제어에 ‘social determinant’가포함된 국외문헌들과, ‘tuberculosis’

Purpose: This study aimed to evaluate the prognosis of the not evaluated (NE) group by comparing it with the lost to follow-up (LTFU) group among patients with multidrug/rifampin-resistant tuberculosis (MDR/RR-TB). Materials and Methods: This was a retrospective longitudinal follow-up study using an integrated database constructed by data linkage of the three national databases. This database included 7226 cases of MDR/RR-TB notified between 2011 and 2017 in South Korea. Results: Among the 7226

In Mycobacterium tuberculosis (MTB) control, whole genome sequencing-based molecular drug susceptibility testing (molDST-WGS) has emerged as a pivotal tool. However, the current reliance on a single-strain reference limits molDST-WGS’s true potential. To address this, we introduce a new pan-lineage reference genome, ‘MtbRf’. We assembled ‘unmapped’ reads from 3,614 MTB genomes (751 L1; 881 L2; 1,700 L3; and 282 L4) into 35 shared, annotated contigs (54 coding sequences [CDSs]). We constructed Mt

OBJECTIVES: Asymptomatic tuberculosis (TB) has gained programmatic recognition in WHO's 2025 framework, but large-scale real-world evidence on its prognosis remains limited. We compared clinical characteristics, treatment outcomes, and post-treatment recurrence between asymptomatic and symptomatic pulmonary TB in South Korea. METHODS: We conducted a nationwide retrospective cohort study linking the Korean National Tuberculosis Surveillance System, National Health Information Database, and cause-

Tuberculosis survivors often face long-term physical, psychological, and social challenges that extend beyond microbiological cure. Post-tuberculosis complications include pulmonary damage, cardiovascular and neurological sequelae, as well as significant impacts on overall wellbeing and livelihoods. Despite increasing awareness, most care continues to focus primarily on lung disease, overlooking the multisystem and social needs of survivors. A holistic, people-centered framework that integrates

BACKGROUND: Many individuals with tuberculosis (TB) experience various psychological problems after TB diagnosis, and they may also have suicidal ideations and suicidal attempts associated with TB-related depression or stigma. Until now, little is known about suicide rates among individuals with TB. We aimed to investigate the trends, characteristics, and contributing factors of suicide deaths among individuals with TB, using a Republic of Korea nationwide cohort. METHODS: This was a retrospecti