이화진 교수

OBJECTIVE: To evaluate the effects of Tai Chi Qigong training on the quality of life and physical function of patients with osteoarthritis of the knee. DESIGN: A preliminary, single-blind, randomized controlled trial. SETTING: General community, performed at Hwaseong City Health Center. PARTICIPANTS: Forty-four elderly subjects (mean age, 69.1 +/- 5.4 years) with knee osteoarthritis. INTERVENTION: The patients were randomized (2:1) to: (1) an eight-week Tai Chi Qigong training programme or (2) a

We have identified three differentially methylated regions associated with gestational age at birth. All three nearby genes play important roles in the development of several organs, including skeletal muscle, brain and haematopoietic system. Therefore, they may provide initial insight into the basis of PTB's negative health outcomes. The genome-wide custom DNA methylation array technology and novel statistical methods employed in this study could constitute a model for epidemiologic studies of

Limitation in cell sources for autologous cell therapy has been a recent focus in stem cell therapy and tissue engineering. Among various research advances, direct conversion, or transdifferentiation, is a notable and feasible strategy for the generation and acquirement of wanted cell source. So far, utilizing cell transdifferentiation technology in tissue engineering was mainly restricted at achieving single wanted cell type from diverse cell types with high efficiency. However, regeneration of

Somatic mutation rates in cancer differ across the genome in a cancer cell-type specific manner. Although key factors that contribute to the differences were identified, the major cancer progression stage when these factors associate with the mutation variance remained poorly investigated. Here, we analyzed whole-genome sequencing data of pre-cancerous and matching cancer tissues from 173 individuals and 423 normal tissue chromatin features to determine the critical stage of these features contr

Vagal withdrawal and sympathetic overactivity accompany various types of stress. Qi training is reported to reduce sympathetic hyper-reactivity in a stressful situation. Turo, which is a type of dance that uses the Meridian Qi System, may reduce the psychological symptoms induced by an imbalance of the autonomic nervous system (ANS). We observed whether Turo training alters psychopathological and psychological symptoms using the Symptom Checklist 90-Revision (SCL-90-R) and examined whether it at

Herein, the effects of various alcohols on lecithin/CaCl2 organogels are investigated. Mixtures of lecithin and CaCl2 form reverse cylindrical micelles, resulting in optically transparent organogels. The addition of various alcohols to a mixture of lecithin and CaCl2 induces a decrease in viscosity through which reverse cylindrical micelles are transformed into spherical micelles (or short cylindrical micelles). Long-hydrocarbon-chain alcohols decrease the viscosity of lecithin/CaCl2 mixtures mo

The older adult population is rapidly increasing in South Korea, and hospitalization at general hospitals is increasing too. Therefore, nurses working at general hospitals need the nursing competency for older adult patients. The study was conducted to examine the effects of nurses' perception of the older adults and work stress on the nursing competency of nurses at a general hospital, South Korea. A cross-sectional, descriptive correlational design was employed. Participants were a total of 13

We present here COOBoostR, a computational method designed for the putative prediction of the tissue- or cell-of-origin of various cancer types. COOBoostR leverages regional somatic mutation density information and chromatin mark features to be applied to an extreme gradient boosting-based machine-learning algorithm. COOBoostR ranks chromatin marks from various tissue and cell types, which best explain the somatic mutation density landscape of any sample of interest. A specific tissue or cell ty

Acquiring adequate number of cells is one of the crucial factors to apply tissue engineering strategies in order to recover critical-sized defects. While the reprogramming technology used for inducing pluripotent stem cells (iPSCs) opened up a direct path for generating pluripotent stem cells, a direct conversion strategy may provide another possibility to obtain desired cells for tissue engineering. In order to convert a somatic cell into any other cell type, diverse approaches have been invest

This study was carried out to analyze the home ranges of three medium-sized mammals(Nyctereutes procyonoides, Prionailurus bengalensis, and Meles leucurus) inhabiting the Sobaeksan National Park, Korea. Three individuals of each species were captured using live traps(Tomahawk live trap 210A) and radio tracking was conducted from June 2012 to May 2014 using VHF and CDMA methods. We determined that the home range of N. procyonoides was <TEX>$6.53{\pm}6.66km^2$</TEX>(MCP 100), <TEX>$3.39{\pm}4.73km

BACKGROUND: The number of patients suffering from osteoporosis is increasing as the elderly population increases. The demand for investigating bone regeneration strategies naturally arises. One of the approaches to induce bone regeneration is somatic cell transdifferentiation. Among the transcriptional regulators for transdifferentiation, octamer-binding transcription factor 4 (OCT4) is famous for its role in the regulation of pluripotency of stem cells. Bone morphogenetic protein 4 (BMP4) is an

여우는 한국에서 1980년대 이후로 절멸된 것으로 취급하고 있으며, 현재는 환경부에서 멸종위기 1급 동물로 지정되어 소백산국립공원에서 복원사업이 이루어지고 있다. 본 연구에서는 여우복원사업에 필요한 적정 모델링과 방사 전략을 수립하기 위하여, VORTEX 프로그램을 이용한 개체군 생존력 분석(Population viability analysis: PVA)을 수행하였다. 초기 개체군 0에서 매년 10개체(암5, 수5)를 향후 10년간 지속적으로 방사할 경우, 개체군의 이입으로 50년간 개체군 성장률은 $0.018{\pm}0.204$ 였으며, 절멸확률은 0.354로 나타났다. 최초 방사 후 16년차에 116.34로 최대 개체군 크기를 보였으나, 17년차부터 매년 1.22의 감소율을 나타내었다. 방사된 여우의 지속적인 성장과 절멸을 방지하기 위해서는 최초 방사 17년 이후 추가적인 방사가 필요하며, 장기적인 여우 존속을 위해서는 매년 12개체 이상을 방사하는 것이 필요한 것으로 분석되었다