임현철 교수

Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate into the esophagus or beyond, resulting in either troublesome symptoms or complications. GERD is heterogeneous in terms of varied manifestations, test findings, and treatment responsiveness. GERD diagnosis can be established with symptomatology, pathology, or physiology. Recently the Lyon consensus defined the "proven GERD" with concrete evidence for reflux, including advanced grade erosive esophagitis (L

With a dramatic growth in the drone market in recent years, the amount of research efforts dedicated to drones increases correspondingly. However, short battery life severely restricts applications of the unmanned aerial vehicles and has proven to be a hard issue to tackle. Among various solutions for this problem, an automatic drone charging station can be utilized. This paper proposes a fully automatic charging station which operates wirelessly. The station also allows for imprecise landing of

BACKGROUND: Rifabutin has been known to be effective in multidrug-resistant Helicobacter pylori-harboring patients undergoing treatment failure for H. pylori infection. AIM: To evaluate the efficacy of 7-day treatment regimen consisting rifabutin daily but increasing the dose of amoxicillin and lansoprazole in patients who have failed first and second eradication and to assess the side effect profiles in South Korea. METHODS: From December 2007 to May 2013, 59 H. pylori-infected patients with tw

Mosapride showed to be effective in preventing delayed gastric emptying and the increase in plasma gastrin level induced by PPI treatment, but did not show prominent clinical symptom improvements.

PURPOSE: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D(2) receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon has not yet been thoroughly investigated. The aim of this study was to investigate the effects of itopride on motor functions of the ileum and colon in guinea pigs. MATERIALS AND METHODS: The distal ileum was excised and the activity of peristaltic contraction was determine

Prokinetics could improve the symptoms of FD by regulating gastric myoelectrical activity, and EGG could be a useful tool in evaluating the effects of various prokinetics.

Postoperative nausea and vomiting (PONV) is considered as a main cause of dissatisfaction after surgery with postoperative pain. Overall incidence of PONV is 30%, and the incidence rate can increase up to 70-80% in high-risk patient groups. The causes of PONV are multifactorial and can largely be categorized as patient risk factors, surgical procedure, and anaesthetic technique. Pharmacological treatments including dopamine antagonist, anti-histamines, anticholinergics, dexamethasone, neurokinin

Purpose: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D2 receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon has not yet been thoroughly investigated. The aim of this study was to investigate the effects of itopride on motor functions of the ileum and colon in guinea pigs. Materials and Methods: The distal ileum was excised and the activity of peristaltic contraction was determined

Radiology, Yonsei University College of Medicine, KoreaMagnet compression anastomo sis is a nonsurgical method that uses two magnets to treat bilio-biliary and bilio-enteric anastomotic strictures after a living donor transplantation. The compression pressure of the two magnets induces ischemic necrosis at the anastomostic stricture and creates a fistula at the stricture site. A choledochal cyst is an uncommon congenital anomaly characterized by dilatation of the biliary tree and can cause obstr

Backgrounds/Aim: Postoperative ileus (POI) is characterized by a transiently impaired propulsive function of the entire gastrointestinal tract which results from activated inhibitory sympathetic neural reflexes in the gut after abdominal surgery. Itopride hydrochloride (itopride) has been known as a gastroprokinetic agent which inhibits acetylcholinesterase and as antagonizes dopamine D2 receptor. The aim of this experiment is to clarify gastrointestinal motility effect of itopride in POI in gui

자석 압박 문합술은 주로 생체간이식환자에서 발생하는 총담관간 단단문합술 또는 총담관-공장문합술 후 발생한 문합부 협착을 두 개의 자석을 이용하여 치료하는 비수술적 방법이다. 두 개의 자석의 압박은 협착부분의 허혈성 괴사를 통한 누공을 형성하여 새로운 문합구를 형성하도록 한다. 담관 낭종은 드문 선천적 질환으로 간내 또는 간외 담관의 확장을 특징으로 하며 패쇄성 황달, 담관염, 담석, 담관암을 유발할 수 있다. 담관 낭종의 치료는 낭종의 완전 절제 및 간관-공장-공장 문합술을 시행하고 있으나, 수술 후 분합부 협착에 의한 간내 담석, 반복적인 담관염이 발생할 수 있다. 협착의 치료를 위하여 내시경적 또는 방사선학적 시술을 시행할 수 있으며, 재수술을 통한 치료는 마지막 방법으로 시도할 수 있다. 저자들은 담관 낭종 절제술 후 문합부 협착에 의한 반복적인 담관염을 주소로 내원하여 자석 압박 문합술로 치료한 증례를 국내에서 처음으로 경험하여 보고한다.