강현식 교수
Hyun‐Sik Kang
성균관대학교 스포츠과학과 · 의학
연구실 소개
강현식 교수의 연구실은 만성질환과 노화 관련 대사 및 운동 기능 저하의 기전을 밝히는 데 초점을 맞추고 있습니다. 비만과 인슐린 저항성, 대사증후군 등 대사질환의 조기 진단 및 예방 전략 개발에 기여하며, 노인기의 근력 저하, 우울증, 근육질환(sarcopenia) 및 골다공로시스와 같은 노화 관련 질환의 분자유전학적 기전을 규명하고 있습니다. 특히 한국인을 대상으로 한 장기적 인구집단 연구를 기반으로 한 생체마커 및 유전자 다형성(예: ACTN3)과의 연관성을 탐색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15PT, especially high-intensity PT, had a favorable effect on several IRS markers in obese adolescents.
Procedure-related thromboembolic events occurred more frequently in patients in the upper quartile with higher PRU, especially in the fourth quartile. Further study including a large number of patients is expected to confirm this finding.
Background . This study investigated the association between insulin resistance (IR) and metabolic syndrome (MetS) in children. Methods . A cross-sectional study involving 1036 healthy children aged between 7 and 13 years was conducted. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as an index of IR. Participants were classified according to the HOMA-IR quartiles. Results . Incremental, linear trends were found in age (<mml:math xmlns:mml="http://www.w3.org/1998/Mat
BACKGROUND: Decreased muscle strength and/or depression with aging are emerging as important public health concerns in both developed and developing countries. This study investigated the effects of low handgrip strength (HGS) and depression on the risk of all-cause mortality in Korean older adults. METHODS: Data from 13,901 Korean adults (57% women) who participated in the 2008 baseline survey and completed the 2011 follow-up assessments were used. RESULTS: In total, the current findings showed
This study examined the association between lifestyle risk factors and all-cause and cardiovascular disease (CVD) mortality in 9945 Korea adults (56% women) aged 45 years and older. Smoking, heavy alcohol intake, underweight or obesity, physical inactivity, and unintentional weight loss (UWL) were included as risk factors. During 9.6 ± 2.0 years of follow-up, there were a total of 1530 cases of death from all causes, of which 365 cases were from CVD. Compared to a zero risk factor (hazard ratio,
Background . Little information is available about molecular markers for sarcopenia and osteoporosis in Asian populations. Objective . This study investigated the association of the ACTN3 polymorphism with sarcopenia and osteoporotic status in older Korean adults. Methods . Older Korean 62 men and 270 women (mean age 73.7 ± 6.6 years) participated in this study. Body mass index, percent body fatness, appendicular skeletal muscle mass, and bone mineral density of the lumbar spine, femur, and tota
This study investigated the effects of exercise preconditioning-induced modification in gut microbiota composition and host responses to cecal ligation and puncture (CLP)-induced sepsis. Four-week-old C57BL/6N male mice were randomly assigned to either CLP ( n = 30) or CLP-exercise (CLP+Exe; n = 30) groups. Prior to CLP-induced sepsis, the CLP+Exe mice were subjected to 8 wk of treadmill running. Fecal samples were collected and analyzed by 16S rRNA amplification sequencing to assess gut microbi
BACKGROUND: Obesity and physical inactivity are associated with higher prevalence of cardiovascular disease (CVD). OBJECTIVE: This study investigated the association between obesity and carotid intima-media thickness (CIMT) stratified by physical activity (PA) in Korean office workers. METHODS: Data obtained from 914 office workers aged 21-60 years (347 women) were used. Resting blood pressures, body mass index (BMI), and waist-to-height ratio (WHtR) were measured. PA was assessed using the inte
The purpose of this study was to investigate the association between physical fitness and mild cognitive impairment (MCI) in elderly Koreans. This was a cross-sectional study that involved 134 men and 299 women aged 65 to 88 years. Six senior fitness tests were used as independent variables: 30 s chair stand for lower body strength, arm curl for upper body strength, chair-sit-and-reach for lower body flexibility, back scratch for upper body flexibility, 8-ft up-and-go for agility/dynamic balance
Background: Little is known regarding the role of eating quickly, physical inactivity, and poor cardiorespiratory fitness (CRF) in assessing the onset of metabolic syndrome (Mets) in Korean young adults. Objectives: This study examined the association between the three risk factors and Mets in 1891 Korean university students (30% female) aged 18–29 years. Methods: Eating speed (slow vs. fast) and physical activity (active vs. inactive) were assessed with a standardized questionnaire. Maximal oxy
n a prospective way, we studied 226 college male students who were apparently healthy and not taking any medications affecting blood pressure, blood lipids, and blood glucose. Following an overnight fasting, 20 ㎖ of venous blood was drawn from an antecubital vein into heparin-treated collection tubes for fasting lipids and glucose assays. Resting blood pressures were also measured in duplicate, of which mean values were used for data analysis. cardiorespiratory(CR) fitness was quantified as minu
PA was inversely and independently associated with all-cause mortality in Korean older adults.
대표 연구 분야
강현식 교수의 연구를 Nubint에서 더 깊이 살펴보세요
이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.