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안익성 교수

Ik-sung Ahn

연세대학교 화공생명공학과 · 생화학·유전·분자생물학

연구실 소개

안익성 교수의 연구실은 주로 환경 생물공학과 생화학적 반응 메커니즘을 기반으로 한 오염물질 제거 기술 및 생체분자 탐지 기술을 연구하고 있습니다. 특히 희토류 환경오염물질인 나이프탈렌과 다환화합물의 생물분해 메커니즘, 고체상에서의 농도 이동 및 흡착 거동을 수학적 모델링을 통해 규명하고 있으며, 카스파이신 B와 같은 생체효소의 선택적 탐지 및 억제제 개발에도 주력하고 있습니다. 나노입자 기반 효소 고정화 기술을 활용한 고효율 생물촉매 개발도 핵심 연구 분야입니다.

생물분해환경오염물질효소 탐지고정화 효소수학적 모델링

연구 현황

논문 수
114
총 인용 수
2,043
최근 5년 논문
14
주요 분야
생화학·유전·분자생물학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
14총합
2019
2020
2021
2023
2025
5개년 연도별 피인용 수
100총합
20192020202120232025

주요 논문

15
1
논문|인용수 88·2003
Effect of additional carbon source on naphthalene biodegradation by Pseudomonas putida G7
Kangtaek Lee, Jinwon Park, Ik‐Sung Ahn
SJR Q1Journal of Hazardous Materials
PollutionEnvironmental Science
2
논문|인용수 79·2012
Adhesion of nano-sized particles to the surface of bacteria: Mechanistic study with the extended DLVO theory
Geelsu Hwang, Ik‐Sung Ahn, Byung Jin Mhin, Ju-Young Kim
SJR Q1Colloids and Surfaces B Biointerfaces
Surfaces, Coatings and FilmsMaterials Science
3
논문|인용수 65·2003
Stability analysis of Bacillus stearothermophilus L1 lipase immobilized on surface-modified silica gels
Sangpill Hwang, Kangtaek Lee, Jin-Won Park, Byoung Ryul Min, Seungjoo Haam, Ik‐Sung Ahn, Joon-Ki Jung
SJR Q2Biochemical Engineering Journal
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
논문|인용수 57·1998
Growth kinetics ofPseudomonas putida G7 on naphthalene and occurrence of naphthalene toxicity during nutrient deprivation
Ik‐Sung Ahn, William C. Ghiorse, Leonard W. Lion, Michael L. Shuler
SJR Q2Biotechnology and Bioengineering

The objectives of this work were (1) to demonstrate how the chemostat approach could be modified to allow determination of kinetic parameters for a sparingly soluble, volatile substrate such as naphthalene and (2) to examine the influence of the interactions of various nutrients on possible growth-inhibitory effects of naphthalene. Pseudomonas putida G7 was used as a model naphthalene-degrading microorganism. Naphthalene was found to be toxic to P. putida G7 in the absence of a nitrogen source o

PollutionEnvironmental Science
5
논문|인용수 47·2008
Product identification of guaiacol oxidation catalyzed by manganese peroxidase
Sangpill Hwang, Chang-Ha Lee, Ik‐Sung Ahn
SJR Q1Journal of Industrial and Engineering Chemistry
Plant ScienceAgricultural and Biological Sciences
6
논문|인용수 43·2007
Absorption of a volatile organic compound by a jet loop reactor with circulation of a surfactant solution: Performance evaluation
Byungjoon Park, Geelsu Hwang, Seungjoo Haam, Chang‐Ha Lee, Ik‐Sung Ahn, Kyoungjoo Lee
SJR Q1Journal of Hazardous Materials
Process Chemistry and TechnologyChemical Engineering
7
논문|인용수 43·2014
Gold Nanoparticles-Based Colorimetric Assay for Cathepsin B Activity and the Efficiency of Its Inhibitors
Chan‐Jin Kim, Dong-Ik Lee, Cheonghee Kim, Kangtaek Lee, Chang‐Ha Lee, Ik‐Sung Ahn
SJR Q1Analytical Chemistry

Cathepsin B has been suggested to be a prognostic marker of melanoma, glioma, and a variety of cancers such as brain, breast, colon, esophageal, gastric, lung, ovarian, and thyroid cancers. Cathepsin B inhibitors have also been considered as anticancer drug candidates; hence, there has been a growing need for a probe which enables the selective and simple detection of cathepsin B and its inhibitors. For the purpose of selective assay, a cathepsin B-specific substrate, N,N'-diBoc-dityrosine-glyci

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
논문|인용수 42·2004
Evaluation of cellulose-binding domain fused to a lipase for the lipase immobilization
Sangpill Hwang, Jungoh Ahn, Sumin Lee, Tai Gyu Lee, Seungjoo Haam, Kangtaek Lee, Ik‐Sung Ahn, Joon-Ki Jung
SJR Q2Biotechnology Letters
Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
논문|인용수 29·2015
Application of the extended DLVO approach to mechanistically study the algal flocculation
Reginah Nabweteme, Mi Ri Yoo, Hyuk Sung Kwon, Youn Joong Kim, Geelsu Hwang, Chang-Ha Lee, Ik‐Sung Ahn
SJR Q1Journal of Industrial and Engineering Chemistry
Water Science and TechnologyEnvironmental Science
10
논문|인용수 28·2010
Analysis of the adhesion of Pseudomonas putida NCIB 9816-4 to a silica gel as a model soil using extended DLVO theory
Geelsu Hwang, Chang‐Ha Lee, Ik‐Sung Ahn, Byung Jin Mhin
SJR Q1Journal of Hazardous Materials
Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
논문|인용수 26·2014
Biofixation of a high-concentration of carbon dioxide using a deep-sea bacterium: Sulfurovum lithotrophicum 42BKTT
Hyuk‐Sung Kwon, Jae-Hyuk Lee, Taekyung Kim, Jae-Jeong Kim, Philip Jeon, Chang‐Ha Lee, Ik‐Sung Ahn
SJR Q1RSC Advances

Biological conversion of high-concentration CO<sub>2</sub>in the emission gases using a deep-sea sulfur oxidizing bacterium.

Renewable Energy, Sustainability and the EnvironmentEnergy
12
논문|인용수 24·2010
Determination of reliable Lewis acid–base surface tension components of a solid in LW–AB approach
Geelsu Hwang, Chang‐Ha Lee, Ik‐Sung Ahn, Byung Jin Mhin
SJR Q1Journal of Industrial and Engineering Chemistry
Biomedical EngineeringEngineering
13
논문|인용수 24·2009
Evaluation of a silica-coated magnetic nanoparticle for the immobilization of a His-tagged lipase
Hyejoo Kim, Hyuk Sung Kwon, Jungoh Ahn, Chang-Ha Lee, Ik‐Sung Ahn
SJR Q3Biocatalysis and Biotransformation

Magnetic particles of size 10 nm have been coated with silica to a mean diameter of 40 nm and charged with Cu2+ ions via a multidentate ligand, iminodiacetic acid (IDA), for the immobilization of His-tagged Bacillus stearothermopilus L1 lipase. Microporous (average pore diameter of 60 Å) silica gel with a mean particle diameter of 115 µm has been used as a comparative support material. The molar ratio of Cu2+ to IDA was found to be 1:1.14 and 1:1.99 in the silica gel and the silica-coated magnet

Molecular BiologyBiochemistry, Genetics and Molecular Biology
14
논문|인용수 24·2012
A dityrosine-based substrate for a protease assay: Application for the selective assessment of papain and chymopapain activity
Chan‐Jin Kim, Dong-Ik Lee, Chang‐Ha Lee, Ik‐Sung Ahn
SJR Q1Analytica Chimica Acta
Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
논문|인용수 24·1999
Validation of a Hybrid “Two-Site Gamma” Model for Naphthalene Desorption Kinetics
Ik‐Sung Ahn, Leonard W. Lion, Michael L. Shuler
SJR Q1Environmental Science & Technology

Three models for sorption/desorption of polycyclic aromatic hydrocarbon (PAH) contaminants from soil were compared for their ability to predict the transport of PAH in soil: a “gamma” model, a “two-site/two-region” nonequilibrium model, and a “hybrid” model. In the “hybrid” model, soil organic matter was conceptually divided into two compartments; a fraction with rapid sorption/desorption kinetics and a compartment with mass-transfer-limited kinetics. Contaminant sorbed in the rapid compartment

Environmental EngineeringEnvironmental Science

대표 연구 분야

Molecular BiologyMaterials ChemistryPollutionPlant ScienceBiomaterialsMechanical Engineering

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