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이인하 교수

Inha Lee

연세대학교 산부인과 · 의학

연구실 소개

이인하 교수의 연구실은 산부인과 및 난소질환 분야에서의 정밀의료와 조직공학 기반 치료 전략을 핵심으로 삼고 있습니다. 특히 난소 기능 저하, 난소암의 생물학적 마커 탐색, 자가세포 기반의 조직 재생 치료 등에 초점을 맞추며, DRG 도입이 임상적 결과에 미치는 영향과 같은 의료정책적 요소와도 연계된 종합적 접근을 펼치고 있습니다. 최근에는 식물성 에스트로겐 성분을 활용한 갱년기 증상 완화 연구를 통해 보다 안전하고 자연스러운 치료법 개발에도 기여하고 있습니다.

난소 기능 재생생물학적 마커자기세포 치료식물성 에스트로겐임상적 경과 분석

연구 현황

논문 수
54
총 인용 수
406
최근 5년 논문
19
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
19총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
66총합
20222023202420252026

주요 논문

15
1
논문|인용수 39·2018
The Effect of Diagnosis-Related Group Payment System on Quality of Care in the Field of Obstetrics and Gynecology among Korean Tertiary Hospitals
Yong Wook Jung, Haeyong Pak, Inha Lee, Eui Hyeok Kim
SJR Q2Yonsei Medical JournalOA

Implementation of DRGs in the field of obstetrics and gynecology among Korean tertiary hospitals led to reductions in the length of stay without increasing outpatient visits and readmission rates. The number of simultaneous surgeries requiring expensive operative instruments and emergency operations decreased after introduction of the DRGs.

General Health ProfessionsHealth Professions
2
논문|인용수 35·2021
Hormone autocrination by vascularized hydrogel delivery of ovary spheroids to rescue ovarian dysfunctions
Hyo‐Jin Yoon, Yong Jae Lee, Sewoom Baek, Young Shin Chung, Dae‐Hyun Kim, Jae Hoon Lee, Yong Cheol Shin, Young Min Shin, Chungsoon Ryu, Hye-Seon Kim, So Hyun Ahn, Heeyon Kim
SJR Q1Science AdvancesOA

The regeneration potential of implantable organ model hydrogels is applied to treat a loss of ovarian endocrine function in women experiencing menopause and/or cancer therapy. A rat ovariectomy model is used to harvest autologous ovary cells while subsequently producing a layer-by-layer form of follicle spheroids. Implantation of a microchannel network hydrogel with cell spheroids [vascularized hydrogel with ovarian spheroids (VHOS)] into an ischemic hindlimb of ovariectomized rats significantly

Public Health, Environmental and Occupational HealthMedicine
3
논문|인용수 35·2018
Pretreatment neutrophil-to-lymphocyte ratio and its dynamic change during neoadjuvant chemotherapy as poor prognostic factors in advanced ovarian cancer
Yun-Ji Kim, Inha Lee, Young Shin Chung, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim, Jung‐Yun Lee
SJR Q2Obstetrics & Gynecology ScienceOA

OBJECTIVE: The purpose of this study was to determine the prognostic implications of the pretreatment neutrophil-to-lymphocyte ratio (NLR) and its dynamic change during chemotherapy in patients with advanced epithelial ovarian cancer undergoing neoadjuvant chemotherapy. METHODS: We performed a retrospective analysis of 203 patients who underwent neoadjuvant chemotherapy prior to interval debulking surgery for advanced-stage ovarian cancer at Yonsei Cancer Hospital between 2007 and 2015. Pretreat

OncologyMedicine
4
논문|인용수 30·2020
Comparison of the therapeutic efficacy and ovarian reserve between catheter-directed sclerotherapy and surgical excision for ovarian endometrioma
Ja Ho Koo, Inha Lee, Kichang Han, Seok Kyo Seo, Man Deuk Kim, Jae Kyung Lee, Joon Ho Kwon, Gyoung Min Kim, Junhyung Lee, Jong Yun Won
SJR Q1European RadiologyOA
Reproductive MedicineMedicine
5
논문|인용수 17·2019
MiR-150-5p May Contribute to Pathogenesis of Human Leiomyoma via Regulation of the Akt/p27Kip1 Pathway In Vitro
Jae Hoon Lee, Young Sik Choi, Ji Hyun Park, Heeyon Kim, Inha Lee, Young Bin Won, Bo Hyon Yun, Joo Hyun Park, Seok Kyo Seo, Byung Seok Lee, SiHyun Cho
SJR Q1International Journal of Molecular SciencesOA

Uterine leiomyoma is found in ~50–80% of women of a reproductive age and is the most common reason for hysterectomy. Recently, posttranscriptional gene silencing by microRNAs (miRs) has been reported as a mechanism for regulating gene expression stability in the pathogenesis of uterine leiomyomas. In this study, miR microarray analysis of leiomyomas and paired myometrial tissue revealed numerous aberrantly expressed miRs, including miR-150. In functional assays, transfection with miR-150 mimic r

Obstetrics and GynecologyMedicine
6
논문|인용수 16·2021
Ovotesticular Disorder of Sex Development in Korean Children: A Single-Center Analysis over a 30-Year Period
Hye In Kim, Inha Lee, Sang Hwa Kim, Yong Seung Lee, Sang Won Han, Bo Hyon Yun
SJR Q2Journal of Pediatric and Adolescent GynecologyOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 16·2021
Comparison between prepubertal and postpubertal patients with obstructed hemivagina and ipsilateral renal anomaly syndrome
Yoo‐Na Kim, Jang Hee Han, Yong Seung Lee, Inha Lee, Sang Won Han, Seok Kyo Seo, Bo Hyon Yun
SJR Q2Journal of Pediatric UrologyOA
Obstetrics and GynecologyMedicine
8
논문|인용수 13·2017
Impact of neoadjuvant chemotherapy and postoperative adjuvant chemotherapy cycles on survival of patients with advanced-stage ovarian cancer
Young Shin Chung, Yun-Ji Kim, Inha Lee, Jung‐Yun Lee, Eun Ji Nam, Sung‐Hoon Kim, Sang Wun Kim, Young Tae Kim
SJR Q1PLoS ONEOA

IDS after 4 cycles of NAC may be a safe and effective option when completing 6 cycles of total chemotherapy. Furthermore, the addition of more than 3 cycles of POAC does not appear to influence the survival of patients achieving completion remission after 3 cycles of POAC.

Reproductive MedicineMedicine
9
논문|인용수 12·2021
Efficacy and Safety of a Standardized Soy and Hop Extract on Menopausal Symptoms: A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Hye In Kim, Min Kyoung Kim, Inha Lee, Jisun Yun, Eui Hyeok Kim, Seok Kyo Seo
The Journal of Alternative and Complementary MedicineOA

Objectives: Soy and hop extracts have been investigated as alternatives for hormone replacement therapy. However, their combined efficacy is not known. We investigated the efficacy and safety of a combined soy and hop extract on postmenopausal symptoms. Design: Double-blinded, randomized controlled trial. Settings/Location: Gynecological outpatient clinic of tertiary hospital. Subjects: Seventy-eight women with moderate or severe menopausal symptoms assessed as modified Kupperman Menopoausal Ind

PharmacologyPharmacology, Toxicology and Pharmaceutics
10
논문|인용수 12·2018
Evaluation of various kinetic parameters of CA-125 in patients with advanced-stage ovarian cancer undergoing neoadjuvant chemotherapy
Yong Jae Lee, Inha Lee, Yun-Ji Kim, Young Shin Chung, Jung‐Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim
SJR Q1PLoS ONEOA

Various kinetic parameters of serum CA-125 have been reported to have better correlation with outcomes for patients treated with neoadjuvant chemotherapy (NAC). This study aimed to compare the available kinetic parameters of serum CA-125 in an external cohort of advanced-stage ovarian cancer. Using the cancer registry databases from the Yonsei Cancer Hospital, we retrospectively reviewed 210 patients with advanced-stage ovarian cancer, treated with NAC followed by interval debulking surgery. We

Reproductive MedicineMedicine
11
논문|인용수 12·2021
Cytokines in culture media of preimplantation embryos during in vitro fertilization: Impact on embryo quality
Inha Lee, So Hyun Ahn, Hye In Kim, Hye Won Baek, Yun Jeong Park, Heeyon Kim, Aminah Ibrahim Aljassim, Whan Shin, Chungsoon Ryu, Jeongmi Yoon, Jae Hoon Lee, Bo Hyon Yun
SJR Q1CytokineOA
ImmunologyImmunology and Microbiology
12
논문|인용수 11·2017
Surgical technique for single-port laparoscopy in huge ovarian tumors: SW Kim's technique and comparison to laparotomy
Jeong Sook Kim, In Ok Lee, Kyung Jin Eoh, Young Shin Chung, Inha Lee, Jung‐Yun Lee, Eun Ji Nam, Sunghoon Kim, Young Tae Kim, Sang Wun Kim
SJR Q2Obstetrics & Gynecology ScienceOA

OBJECTIVE: This study aimed to introduce a method to remove huge ovarian tumors (≥15 cm) intact with single-port laparoscopic surgery (SPLS) using SW Kim's technique and to compare the surgical outcomes with those of laparotomy. METHODS: -sized 3XL LapBag or laparotomy (n=22) for a huge ovarian tumor from December 2008 to May 2016. Perioperative surgical outcomes were compared. RESULTS: =0.045). Patient-controlled anesthesia was used less in the SPLS group (61.9% vs. 100%). CONCLUSION: SPLS was

SurgeryMedicine
13
논문|인용수 11·2020
Identification of Serum Biomarkers for Diagnosis of Endometriosis Using Multiplex Immunoassays
Heeyon Kim, Young Sik Choi, Jeong Sook Kim, Sinae Kim, Bo Hee Won, Young Bin Won, Inha Lee, Jae Hoon Lee, Bo Hyon Yun, Seok Kyo Seo, Joo Hyun Park, SiHyun Cho
SJR Q1Reproductive SciencesOA
Reproductive MedicineMedicine
14
논문|인용수 10·2018
A risk prediction model for medical treatment failure in tubal pregnancy
Jae Hoon Lee, Sung‐Hoon Kim, Inha Lee, Jisun Yun, Bo Hyon Yun, Young Sik Choi, Byung Seok Lee, Seok Kyo Seo
SJR Q2European Journal of Obstetrics & Gynecology and Reproductive BiologyOA
Public Health, Environmental and Occupational HealthMedicine
15
논문|인용수 10·2021
Predictive Factors of Conception and the Cumulative Pregnancy Rate in Subfertile Couples Undergoing Timed Intercourse With Ultrasound
So Hyun Ahn, Inha Lee, SiHyun Cho, Hye In Kim, Hye Won Baek, Jae Hoon Lee, Yun Jeong Park, Heeyon Kim, Bo Hyon Yun, Seok Kyo Seo, Joo Hyun Park, Young Sik Choi
SJR Q1Frontiers in EndocrinologyOA

The aim of this study was to determine predictive factors for pregnancy and assess the cumulative pregnancy rate (CPR) and live birth rate (CLBR) in subfertile couples undergoing timed intercourse (TI) using ultrasound. This retrospective cohort study included 285 women (854 cycles) who started TI with ultrasound between January 2017 and October 2019. The overall clinical pregnancy rate was 28.1% (80/285) per couple and 9.4% (80/854) per cycle. Pregnant women had a higher body mass index (BMI),

Reproductive MedicineMedicine

대표 연구 분야

Reproductive MedicinePublic Health, Environmental and Occupational HealthMolecular BiologyObstetrics and GynecologyImmunologyGeneral Health Professions

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