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윤자경 교수

Ja-Keung Yoon

연세대학교 영상의학과 · 의학

연구실 소개

윤자경 교수의 연구실은 복합영상진단과 정밀의료를 기반으로 한 첨단 영상진단 기술의 개발과 임상 적용을 핵심으로 삼고 있습니다. 특히 간암 진단을 위한 MRI 영상 기법(예: C-SENSE, EOB-MRI), 암의 분자생물학적 특성과 연관된 대사단백질 발현 분석, 그리고 인공지능 기반 소아 장중풍 진단 알고리즘 개발 등 다양한 영역에서 다학제적 연구를 수행하고 있습니다. 최근에는 뇌·간·췌장 등 특정 암의 조기진단 및 예후 예측을 위한 영상생물지표 개발에도 주력하고 있습니다.

영상진단간암인공지능암생물지표정밀의료

연구 현황

논문 수
32
총 인용 수
423
최근 5년 논문
23
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
23총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
170총합
20212022202320242025

주요 논문

15
1
논문|인용수 81·2009
An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
Min Su Kim, Seoyoung Kim, Ja Kyung Yoon, Yin-Won Lee, Yong‐Sun Bahn
SJR Q2Biochemical and Biophysical Research Communications
EpidemiologyMedicine
2
논문|인용수 46·2019
Compressed Sensing and Parallel Imaging for Double Hepatic Arterial Phase Acquisition in Gadoxetate-Enhanced Dynamic Liver Magnetic Resonance Imaging
Ja Kyung Yoon, Myeong‐Jin Kim, Sunyoung Lee
SJR Q1Investigative RadiologyOA

OBJECTIVES: The aim of this study was to investigate the utility of a combined compressed sensing and parallel imaging (C-SENSE) technique for single breath-hold, double arterial phase (AP) examinations in gadoxetate-enhanced magnetic resonance imaging (MRI) of the liver. MATERIALS AND METHODS: We retrospectively reviewed single breath-hold, double AP images obtained by using a C-SENSE technique for gadoxetate-enhanced dynamic liver MRI in a total of 127 patients (89 men and 38 women; mean age,

Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 37·2020
Application of Liver Imaging Reporting and Data System version 2018 ancillary features to upgrade from LR-4 to LR-5 on gadoxetic acid–enhanced MRI
Sunyoung Lee, Seung‐seob Kim, Heejin Bae, Jaeseung Shin, Ja Kyung Yoon, Myeong‐Jin Kim
SJR Q1European RadiologyOA
HepatologyMedicine
4
리뷰|인용수 32·2021
LI‐RADS Major Features on MRI for Diagnosing Hepatocellular Carcinoma: A Systematic Review and Meta‐Analysis
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Yong Eun Chung, Jin‐Young Choi, Mi‐Suk Park
SJR Q1Journal of Magnetic Resonance ImagingOA

BACKGROUND: The reported diagnostic performance for hepatocellular carcinoma (HCC) of each major imaging feature on MRI using standardized definitions of the Liver Imaging Reporting and Data System (LI-RADS) is variable. It is important to know the actual performance of each LI-RADS major imaging feature for imaging diagnosis of HCC and determine the sources of heterogeneity between the reported results. PURPOSE: To systematically determine the performance of each major imaging feature of LI-RAD

HepatologyMedicine
5
리뷰|인용수 31·2022
MRI features of histologic subtypes of hepatocellular carcinoma: correlation with histologic, genetic, and molecular biologic classification
Ja Kyung Yoon, Jin‐Young Choi, Hyungjin Rhee, Young Nyun Park
SJR Q1European RadiologyOA
SurgeryMedicine
6
논문|인용수 30·2021
Reference Values for Skeletal Muscle Mass at the Third Lumbar Vertebral Level Measured by Computed Tomography in a Healthy Korean Population
Ja Kyung Yoon, Sunyoung Lee, Kyung Won Kim, Ji Eun Lee, Jeong Ah Hwang, Taeyong Park, Jeongjin Lee
SJR Q1Endocrinology and MetabolismOA

Our data provide sex-specific cutoff values for the SMA and SMI at the L3 level measured by CT imaging in a healthy Korean population, which may be applicable for identifying sarcopenia in this population.

PhysiologyMedicine
7
논문|인용수 25·2019
Performance of deep learning-based algorithm for detection of ileocolic intussusception on abdominal radiographs of young children
Sung‐Won Kim, Haesung Yoon, Mi‐Jung Lee, Myung‐Joon Kim, Kyunghwa Han, Ja Kyung Yoon, Hyung Cheol Kim, Jaeseung Shin, Hyun Joo Shin
SJR Q1Scientific ReportsOA

The purpose of this study was to develop and test the performance of a deep learning-based algorithm to detect ileocolic intussusception using abdominal radiographs of young children. For the training set, children (≤5 years old) who underwent abdominal radiograph and ultrasonography (US) for suspicion of intussusception from March 2005 to December 2017 were retrospectively included and divided into control and intussusception groups according to the US results. A YOLOv3-based algorithm was deve

SurgeryMedicine
8
논문|인용수 21·2014
Implications of differences in expression of sarcosine metabolism-related proteins according to the molecular subtype of breast cancer
Ja Kyung Yoon, Do Hee Kim, Ja Seung Koo
SJR Q1Journal of Translational MedicineOA

BACKGROUND: The goal of this study was to investigate the expression of sarcosine metabolism-related proteins, namely glycine N-methyltransferase (GNMT), sarcosine dehydrogenase (SARDH), and l-pipecolic acid oxidase (PIPOX), in the different breast cancer subtypes and to assess the implications of differences in expression pattern according to subtype. METHODS: We analyzed the expression of GNMT, SARDH, and PIPOX in a tissue microarray of 721 breast cancer cases using immunohistochemistry (IHC).

Cancer ResearchBiochemistry, Genetics and Molecular Biology
9
논문|인용수 20·2018
Five-year clinical outcomes of uterine artery embolization for symptomatic leiomyomas: An analysis of risk factors for reintervention
Ja Kyung Yoon, Kichang Han, Man Deuk Kim, Gyoung Min Kim, Joon Ho Kwon, Jong Yun Won, Do Yun Lee
SJR Q1European Journal of RadiologyOA
Obstetrics and GynecologyMedicine
10
논문|인용수 16·2022
Regional lymph node metastasis detected on preoperative CT and/or FDG-PET may predict early recurrence of pancreatic adenocarcinoma after curative resection
Ja Kyung Yoon, Mi‐Suk Park, Seung‐seob Kim, Kyunghwa Han, Hee Seung Lee, Seungmin Bang, Ho Kyoung Hwang, Sang Hyun Hwang, Mijin Yun, Myeong‐Jin Kim
SJR Q1Scientific ReportsOA

Abstract The objective of this study was to evaluate the role of regional lymph node (LN) metastasis detected on preoperative CT and/or 18 F-fluoro-2-deoxyglucose-positron emission tomography (FDG-PET) scans in the prediction of early tumor recurrence after curative surgical resection of pancreatic ductal adenocarcinoma (PDAC). This retrospective study included 137 patients who underwent upfront surgery with R0 resection of PDAC between 2013 and 2016. Regional LN metastasis was identified using

OncologyMedicine
11
논문|인용수 11·2020
Strap muscle invasion in differentiated thyroid cancer does not impact disease-specific survival: a population-based study
Ja Kyung Yoon, Jandee Lee, Eun‐Kyung Kim, Jung Hyun Yoon, Vivian Youngjean Park, Kyunghwa Han, Jin Young Kwak
SJR Q1Scientific ReportsOA

TNM staging system of differentiated thyroid cancer defines gross strap muscle invasion as T3b stage. However, the impact of strap muscle invasion on disease-specific survival (DSS) remains controversial. To elucidate the survival impact of strap muscle invasion of any degree in thyroid cancers, the Surveillance, Epidemiology, and End Results (SEER) database (1973-2018) was queried for thyroid cancer only patients on July 2019 (n = 19,914). The Cox proportional hazard analysis with multivariable

Endocrinology, Diabetes and MetabolismMedicine
12
논문|인용수 10·2017
Mesocaval Shunt Creation for Jejunal Variceal Bleeding with Chronic Portal Vein Thrombosis
Ja Kyung Yoon, Man Deuk Kim, Do Yun Lee, Seok Joo Han
SJR Q2Yonsei Medical JournalOA

The creation of transjugular intrahepatic portosystemic shunt (TIPS) is a widely performed technique to relieve portal hypertension, and to manage recurrent variceal bleeding and refractory ascites in patients where medical and/or endoscopic treatments have failed. However, portosystemic shunt creation can be challenging in the presence of chronic portal vein occlusion. In this case report, we describe a minimally invasive endovascular mesocaval shunt creation with transsplenic approach for the

HepatologyMedicine
13
논문|인용수 10·2024
Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue
Sewoom Baek, Hyun‐Su Ha, Jeong Su Park, M CHO, Hye-Seon Kim, Seung Eun Yu, Seyong Chung, Chansik Kim, J. W. Kim, Ji Youn Lee, Yerin Lee, Hyun-Jae Kim
SJR Q1Nature CommunicationsOA

Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical approaches based on tumor avatar models. However, location-dependent oxygen concentrations resulting from the dual hepatic vascular supply drive the inherent heterogeneity of the tumor microenvironment, which presents challenges in developing an avatar model. In this study, tissue samples from 12 patients with hepatocellular carcinoma are cultured directly on a chip and separated based on preference of

Biomedical EngineeringEngineering
14
리뷰|인용수 9·2023
Diagnostic Performance of the 2018 EASL vs. LI‐RADS for Hepatocellular Carcinoma Using CT and MRI: A Systematic Review and Meta‐Analysis of Comparative Studies
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Yun Ho Roh
SJR Q1Journal of Magnetic Resonance ImagingOA

BACKGROUND: Hepatocellular carcinoma (HCC) can be diagnosed without pathologic confirmation in high-risk patients. Therefore, it is necessary to compare current imaging criteria for noninvasive-diagnosis of HCC. PURPOSE: To systematically compare performance of 2018 European Association for the Study of the Liver (EASL) criteria and Liver Imaging Reporting and Data System (LI-RADS) for noninvasive-diagnosis of HCC. STUDY TYPE: Systematic review and meta-analysis. SUBJECTS: Eight studies with 223

HepatologyMedicine
15
논문|인용수 9·2025
Application of LI-RADS CT/MRI Radiation Treatment Response Assessment Version 2024: a study after transarterial radioembolization for hepatocellular carcinoma
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Kyowon Gu, Sun‐Young Baek, Dongho Hyun, Gyoung Min Kim, Jong Yun Won
SJR Q2Japanese Journal of Radiology
HepatologyMedicine

대표 연구 분야

HepatologyEpidemiologyRadiology, Nuclear Medicine and ImagingSurgeryPhysiologyEndocrinology, Diabetes and Metabolism

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