구자설 교수

A diagnostic delay was associated with poor outcomes, such as increased intestinal surgery risks in patients with CD and UC.

The effectiveness of colonoscopy is highly dependent on the quality of bowel preparation. Although many studies have previously evaluated the role of cleansing methods and dosing regimens, few have examined the association between bowel habits and subsequent bowel preparation. Here, we aimed to evaluate the impact of bowel habits on the quality of bowel preparation.A total of 404 patients who underwent a total colonoscopy and completed a personal bowel habit questionnaire at Korea University Hos

Abdominal tuberculosis is a rare manifestation of tuberculosis and sometimes offers difficulties in diagnosis. In this regard colonoscopy with targeted biopsy may be a valuable help to differentiate tuberculous lesions from other diseases of the large bowel. Nodular lesions with areas of polypoid changes are the major gross appearence sometimes simulating neoplastic changes.

Palliative care utilization increased over time and was inversely associated with hospital charges and performing procedures among colorectal cancer patients. Our findings warrant further research and interventions to increase palliative care utilization in colorectal cancer.

Our study showed that abdominal circumference is an independent risk factor for EE, demonstrating a temporal relationship between abdominal obesity and EE.

The use of colonoscopy for the screening and surveillance of colorectal cancer has increased. However, the miss rate of advanced colorectal neoplasm is known to be 2% to 6%, which could be affected by the image intensity of colorectal lesions. Image-enhanced endoscopy (IEE) is capable of highlighting lesions, which can improve the colorectal adenoma detection rate and diagnostic accuracy. Equipment-based IEE methods, such as narrow band imaging (NBI), Fujinon intelligent color enhancement (FICE)

BACKGROUND AND AIM: The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high-risk findings (HRF) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonosco

Background/Aims: There is increasing interest in the use of propofol as a sedative agent for colonoscopy. We evaluated the safety and efficacy of the synergistic sedation with midazolam combined with low-dose propofol versus that of midazolam alone. Methods: A total of 56 patients from among those who underwent total colonoscopy between August 2004 and October 2004 were randomly assigned to one of three medication treatment groups. Group A (n=18) received low-dose midazolam (0.03 mg/kg IV) plus

TJP-008 is a new low-volume cleansing agent with a colon cleansing efficacy comparable to that of standard 2LPEG that exhibits significant safety and tolerability.

Background/Aims: Obesity is reported to be associated with erosive esophagitis (EE). However, the temporal association of obesity and abdominal obesity with EE is unclear. We conducted this study to investigate the temporal association of obesity, especially abdominal obesity with EE. Methods: Among 1,182 subjects who underwent health screening examinations including upper endoscopy in both 2003 and 2006, a total 1,029 subjects with a normal esophagogastric junction on upper endoscopy in 2003 we

Uncontrolled chronic inflammation and necrosis is characteristic of inflammatory bowel disease (IBD). This study aimed to investigate the effect of necrosis inhibitor (NI, NecroX-7) on a dextran sulfate sodium (DSS) induced chronic colitis model of mice. DSS was administered on days 1-5, and the NI was administered intraperitoneally (3 mg/kg, 30 mg/kg) on days 1, 3, and 5 as well as every other day during the first five days of a three-week cycle. Three cycles of administration were performed. C

내시경검사에 진정제를 사용하는 의식하 진정 내시경검사는 점차 증가하고 있으며 벤조다이아제핀과 아편유사제가 흔히 사용되었다. Midazolam은 다른 벤조다이아제핀계 약물보다 효과가 빠르게 나타나고 지속시간이 짧은 장점이 있으나 부작용으로 호흡억제가 발생할 수 있다. 그러나, 벤조다이아제핀 길항제인 flumazenil을 사용하여 midazolam의 호흡억제 효과를 감소시킬 수 있다. Midazolam과 아편유사제의 병합은 효과적이며 안전한 진정방법으로 일반적인 상부위장관 내시경과 대장내시경 검사에 적합하다. Propofol은 지용성으로 midazolam보다 진정 유도와 회복이 빠른 장점이 있으나 저혈압과 일시적 무호흡이 보고되어 주의가 필요하다. 내시경 의사의 감독 하에 적절하게 훈련받은 의료인에 의한 propofol 투여는 효과적이고 안전하며, propofol 투여 방법으로는 간호사가 환자를 감시하면서 propofol을 투약하는 nurse-administered propofol se

The use of colonoscopy for the screening and surveillance of colorectal cancer has increased. However, the miss rate of advanced colorectal neoplasm is known to be 2% to 6%, which could be affected by the image intensity of colorectal lesions. Image-enhanced endoscopy (IEE) is capable of highlighting lesions, which can improve the colorectal adenoma detection rate and diagnostic accuracy. Equipment-based IEE methods, such as narrow band imaging (NBI), Fujinon intelligent color enhancement (FICE)