고재철 교수
Jae-Chul Ko
고려대학교 마취통증의학과 · 의학
연구실 소개
고재철 교수의 연구실은 마취 및 통증 관리 분야에서 환자의 안전과 편안함을 최우선으로 삼는 임상 연구를 중심으로 전개되고 있습니다. 특히 유도기 및 회복기 마취에서 기침 억제, 통증 완화, 기도 관리의 최적화를 위한 약물 용량 조절과 신기술 적용에 초점을 맞추고 있으며, 고령 환자와 청소년 환자의 통증 반응 및 부작용 차이 분석을 통해 개인화된 통증 치료 전략을 모색하고 있습니다. 또한, 가상현실 기반의 수술 시뮬레이터 개발을 통해 의료 교육의 혁신을 선도하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15This randomised, double-blinded, controlled trial was designed to identify the optimal dose of remifentanil for cough suppression without adverse effects during emergence from sevoflurane-remifentanil anaesthesia for thyroidectomy. One hundred and four patients were randomly assigned to maintain target effect-site concentrations of remifentanil at 0 (control group), 1.0 (remifentail 1 group), or 1.5 ng.ml(-1) (remifentanil 1.5 group) during emergence. The incidence of coughing was lower in the r
In this retrospective study, data of 2,435 patients who received fentanyl and ropivacaine-based patient-controlled epidural analgesia (PCEA) for pain relief after elective surgery under general or spinal anesthesia were reviewed. Differences in postoperative pain, incidence of patient-controlled analgesia (PCA)-related adverse effects, and risk factors for the need for rescue analgesics for 48 hours postsurgery in young (age 20-39 years) and elderly (age ≥70 years) patients were evaluated. Altho
BACKGROUND: For patients suspicious of cervical spine injury, a Philadelphia cervical collar is usually applied. Application of Philadelphia cervical collar may cause difficult airway. The aim of this study was to evaluate the laryngeal view and the success rate at first intubation attempt of the Airtraq and conventional laryngoscopy in patients with simulated cervical spine injury after application of a Philadelphia cervical collar. METHODS: Anesthesia was induced with propofol, remifentanil, a
In this retrospective analysis of 10,575 patients who used fentanyl-based intravenous patient-controlled analgesia (IV-PCA) after surgery, we evaluated difference between young and elderly patients on their characteristic of adverse effects.We reviewed the data collected from the patients who were provided IV-PCA for pain control following elective surgery under either general or spinal anesthesia between September 2010 and March 2014. Postoperative pain, incidence of PCA-related adverse effects
Registered at ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT03108989). Registration number: NCT03108989.
BACKGROUND: Since the onset of the coronavirus disease 2019 pandemic, virtual simulation has emerged as an alternative to traditional teaching methods as it can be employed within the recently established contact-minimizing guidelines. This prospective education study aimed to develop a virtual reality simulator for a lumbar transforaminal epidural block (LTFEB) and demonstrate its efficacy. METHODS: We developed a virtual reality simulator using patient image data processing, virtual X-ray gene
BACKGROUND: The location and the number of lumbar sympathetic ganglia (LSG) vary between individuals. The aim of this study was to determine the appropriate level for a lumbar sympathetic ganglion block (LSGB), corresponding to the level at which the LSG principally aggregate. METHODS: Seventy-four consecutive subjects, including 31 women and 31 men, underwent LSGB either on the left (n = 31) or the right side (n = 43). The primary site of needle entry was randomly selected at the L3 or L4 verte
Increase in airway pressure resulting from placement into a prone position may predict intraoperative surgical blood loss.
목적: 생선 섭취 빈도와 혈중 수은 농도간의 관련성을 파악하고자 본 연구를 수행하였고 본 연구의 결과를 바탕으로 생선 섭취가 높은 집단에 대한 수은 노출 실태 파악하여 중, 장기적인 대책을 위한 기초자료를 제공 하고자 한다. 방법: 경상남도 거제시 2개 어촌 마을과 창원시 2개 농촌 마을을 방문하여 어촌 164명(남자:62명, 여자:102명), 농촌 219명(남자:84명, 여자:135명)을 대상으로 연구를 수행하였다. 연구진의 마을 방문 시 본 연구 목적과 방법, 유익성에 대해서 설명을 한 뒤 참가 희망자에 한하여 조사자들이 설문지를 직접 읽어주고 기입하는 방식으로 설문조사를 진행하였다. 설문 조사 내용은 연령, 성별, 음주, 흡연, 생선 섭취빈도, 거주기간, 거주 지역, 학력, 직업력 등 이었고 현재 건강 상태는 의사의 문진을 통하여 이루어졌다. 결과: 생선 섭취 빈도를 한 달에 2~3회 이하, 일주일에 1~2회, 일주일에 3~4회 이상 섭취 군으로 나누었다. 각 군에서의 혈중 수
Paravertebral muscle twitching while performing lumbar RF-MB may be a reliable predictor of long-term efficacy when sensory provocation under 0.5 V is achieved. However, further investigation may be necessary for clarifying its clinical significance.
OBJECTIVE: Technological developments have made it possible to create simulation models to educate clinicians on surgical techniques and patient preparation. In this study, we created an inexpensive lumbar spine phantom using patient data and analyzed its usefulness in clinical education. METHODS: This randomized comparative study used computed tomography and magnetic resonance imaging data from a single patient to print a three-dimensional (3D) bone framework and create a mold. The printed bone
The current landmark for genicular nerve procedures may not accurately target the correct nerve position, or reduce the risk for vessel damage. A more proximal target may reduce complications and increase the probability of successful procedures, although clinical correlation is needed.
The EC50 of the sevoflurane concentration was 3.0, 2.0, and 1.29 vol% when it was combined with a bolus dose of remifentanil of 1.0, 1.5, and 2.0 μg/kg, respectively. Of the 3 different bolus doses of remifentanil, the dose of 1.5 μg/kg was least associated with changes in the HR/mean blood pressure during intubation without increasing adverse effects.
Objectives: Augmented reality (AR) navigation systems are emerging to simplify and enhance the precision of medical procedures. Lumbosacral transforaminal epidural injection is a commonly performed procedure for the treatment and diagnosis of radiculopathy. Accurate needle placement while avoiding critical structures remains a challenge. For this purpose, we conducted a randomized controlled trial for our augmented reality navigation system. Methods: This randomized controlled study involved 28
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