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차재국 교수

Jae-Guk Cha

연세대학교 치주과 · 치의학

연구실 소개

차재국 교수의 연구실은 치과 임플란트 주변염(퍼피-임플란티스)의 비수술적 및 수술적 치료 전략, 특히 국소 항생제(미노시클린, 메트로니다졸)의 적용 효과와 뼈 재생 기술에 중점을 두고 있습니다. 특히, 임플란트 주변 뼈 손실을 복구하고 예방하기 위한 생체모방 뼈 대체재(예: 하이드로우레오파이트, BMP-2)의 임상적 유효성과 표면 처리 기술의 영향을 실험적으로 평가하고 있습니다. 또한, 콘바이어-컴퓨터 톰로그라피(CBCT)를 활용한 정밀한 뼈 변화 분석과 임플란트 표면의 미세구조적 변화를 동시에 고려한 종합적 접근을 펼치고 있습니다.

퍼피-임플란티스국소 항생제뼈 재생CBCT 분석임플란트 표면 처리

연구 현황

논문 수
192
총 인용 수
2,343
최근 5년 논문
63
주요 분야
치의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
63총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
373총합
20222023202420252026

주요 논문

15
1
논문|인용수 103·2019
Surgical Therapy of Peri-Implantitis with Local Minocycline: A 6-Month Randomized Controlled Clinical Trial
Jae‐Kook Cha, Jung‐Seok Lee, Chang‐Sung Kim
SJR Q1Journal of Dental ResearchOA

The purpose of this study was to determine the clinical, microbial, and radiographic effects of local minocycline combined with surgical treatment of peri-implantitis. Fifty patients with peri-implantitis were recruited, and surgical treatment with the local application of either minocycline or placebo ointment was performed. The application of minocycline was repeated with supragingival debridement at 1, 3, and 6 mo postoperatively. Plaque index, gingival index (GI), probing pocket depth (PPD),

PeriodonticsDentistry
2
논문|인용수 82·2019
Alveolar ridge preservation in the posterior maxilla reduces vertical dimensional change: A randomized controlled clinical trial
Jae‐Kook Cha, Young Woo Song, Suhyun Park, Ronald E. Jung, Ui‐Won Jung, Daniel S. Thoma
SJR Q1Clinical Oral Implants ResearchOA

OBJECTIVES: To test whether or not alveolar ridge preservation reduces vertical changes in the posterior maxilla compared to spontaneous healing following tooth extraction. MATERIALS AND METHODS: Forty subjects requiring extraction of maxillary posterior teeth with root apices protruding into the maxillary sinus floor were consecutively enrolled. Patients were randomly assigned to either one of two surgical interventions: an alveolar ridge preservation procedure using collagenated bovine bone mi

Oral SurgeryDentistry
3
논문|인용수 67·2019
The effect of five mechanical instrumentation protocols on implant surface topography and roughness: A scanning electron microscope and confocal laser scanning microscope analysis
Jae‐Kook Cha, Kyeong‐Won Paeng, Ui‐Won Jung, Seong‐Ho Choi, Mariano Sanz, Ignacio Sanz‐Martín
SJR Q1Clinical Oral Implants ResearchOA

OBJECTIVE: To evaluate in vitro the changes in implant surface topography and roughness of commercial implants after instrumentation with five decontamination protocols. MATERIAL AND METHODS: Seventy-two titanium implants with a sandblasted and acid-etched (SLA) surface were placed 5 mm supra-crestally. Five groups of twelve implants were instrumented with the following protocols: a metal scaler tip (SCAL), a thermoplastic scaler tip (PEEK), a round titanium brush (RBRU), a tufted brush with tit

Oral SurgeryDentistry
4
논문|인용수 51·2020
Significance of implant design on the efficacy of different peri-implantitis decontamination protocols
Ignacio Sanz‐Martín, Kyeong‐Won Paeng, Hyobin Park, Jae‐Kook Cha, Ui‐Won Jung, Mariano Sanz
SJR Q1Clinical Oral InvestigationsOA
Oral SurgeryDentistry
5
논문|인용수 49·2021
Programmed BMP-2 release from biphasic calcium phosphates for optimal bone regeneration
Seora Han, Kyeong‐Won Paeng, Sohyeon Park, Ui‐Won Jung, Jae‐Kook Cha, Jinkee Hong
SJR Q1BiomaterialsOA
Biomedical EngineeringEngineering
6
논문|인용수 47·2013
Sinus augmentation using BMP‐2 in a bovine hydroxyapatite/collagen carrier in dogs
Jae‐Kook Cha, Jung‐Seok Lee, Min‐Soo Kim, Seong‐Ho Choi, Kyoo‐Sung Cho, Ui‐Won Jung
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: The objective of this study was to determine the efficacy of bone morphogenetic protein 2 (BMP-2) in a bovine hydroxyapatite/collagen (BHC) carrier to augment bone formation in a canine nasal sinus model. METHODS: Eight mongrel dogs, approximately 12 months old and 30 kg in weight were used. Following preparation of bilateral sinus access windows, BHC alone (control) or loaded with E. coli-derived BMP-2 at 0.1 mg/ml was implanted in four animals, and BHC loaded with E. coli-derived BMP-2 at

Oral SurgeryDentistry
7
논문|인용수 42·2021
Adjunctive use of metronidazole‐minocycline ointment in the nonsurgical treatment of peri‐implantitis: A multicenter randomized controlled trial
Seung‐Hyun Park, Young Woo Song, Jae‐Kook Cha, Jung‐Seok Lee, Young‐Taek Kim, Hyun‐Seung Shin, Dong‐Won Lee, Jae Hyun Lee, Chang‐Sung Kim
SJR Q1Clinical Implant Dentistry and Related ResearchOA

BACKGROUND: Clinical benefits of local antibiotics as an adjunct to nonsurgical treatment of peri-implantitis have been widely reported, but most studies evaluated incipient peri-implantitis lesions, and showed incomplete treatment success rates. PURPOSE: To assess the clinical and microbiological outcomes of administering metronidazole in combination with minocycline as a local adjunct to the nonsurgical treatment of peri-implantitis. MATERIALS AND METHODS: One hundred and eighteen subjects wit

Oral SurgeryDentistry
8
논문|인용수 36·2011
The influence of perforating the autogenous block bone and the recipient bed in dogs. Part II: histologic analysis
Jae‐Kook Cha, Chang‐Sung Kim, Seong‐Ho Choi, Kyoo‐Sung Cho, Jung‐Kiu Chai, Ui‐Won Jung
SJR Q1Clinical Oral Implants Research

It was conjectured that intentional cortical perforation of the recipient bed and the ABB might enhance the initial angiogenesis and the integration of the graft.

UrologyMedicine
9
논문|인용수 33·2024
Wide Restorative Emergence Angle Increases Marginal Bone Loss and Impairs Integrity of the Junctional Epithelium of the Implant Supracrestal Complex: A Preclinical Study
Franz Josef Strauß, Jin‐Young Park, Jung‐Seok Lee, Lucia Schiavon, Rawen Smirani, Sonja Hitz, Jennifer G. M. Chantler, Nikos Mattheos, Ronald E. Jung, Dieter D. Bosshardt, Jae‐Kook Cha, Daniel S. Thoma
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: To assess the influence of the emergence angle on marginal bone loss (MBL) and supracrestal soft tissue around dental implants. MATERIALS AND METHODS: In six mongrel dogs, the mandibular premolars and molars were extracted. After 3 months of healing, four dental implants were placed in each hemimandible. The implants were randomly allocated to receive one of four customized healing abutments, each with a different value of the restorative emergence angle: 20°, 40°, 60° or 80°. Intra-oral ra

Oral SurgeryDentistry
10
논문|인용수 29·2011
Case series of maxillary sinus augmentation with biphasic calcium phosphate: a clinical and radiographic study
Jae‐Kook Cha, Jung‐Chul Park, Ui‐Won Jung, Chang‐Sung Kim, Kyoo‐Sung Cho, Seong‐Ho Choi
SJR Q1Journal of Periodontal & Implant ScienceOA

It can be suggested that Osteon may have predictable result when it was used as a grafting material for sinus floor augmentation.

Oral SurgeryDentistry
11
논문|인용수 24·2021
Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial
Jin‐Young Park, Kyung‐A Ko, Jiyeong Lee, Yoogyeong Oh, Hyun‐Chang Lim, Dong‐Woon Lee, Seong‐Ho Choi, Jae‐Kook Cha
SJR Q1NutrientsOA

BACKGROUND: Mangosteen and propolis extracts (MAEC) have been potential therapeutic agents known to exhibit powerful antioxidant and anti-inflammatory properties. The aim of the current study was to evaluate the clinical and immunological efficacy of MAEC as well as safety and patient-reported outcomes (PROMs) on gingivitis and incipient periodontitis. METHODS: This study was performed on 104 patients diagnosed with gingivitis or incipient periodontitis. At baseline, the participants were random

Insect ScienceAgricultural and Biological Sciences
12
논문|인용수 23·2023
Occlusive membranes for guided regeneration of inflamed tissue defects
Woojin Choi, Utkarsh Mangal, Jin‐Young Park, Ji‐Yeong Kim, Taesuk Jun, Ju Won Jung, Moonhyun Choi, Sung-Won Jung, Milae Lee, Ji-Yeong Na, Du Yeol Ryu, Jin‐Man Kim
SJR Q1Nature CommunicationsOA

Guided bone regeneration aided by the application of occlusive membranes is a promising therapy for diverse inflammatory periodontal diseases. Symbiosis, homeostasis between the host microbiome and cells, occurs in the oral environment under normal, but not pathologic, conditions. Here, we develop a symbiotically integrating occlusive membrane by mimicking the tooth enamel growth or multiple nucleation biomineralization processes. We perform human saliva and in vivo canine experiments to confirm

UrologyMedicine
13
논문|인용수 23·2019
Maxillary sinus augmentation using biphasic calcium phosphate: dimensional stability results after 3–6 years
Jae‐Kook Cha, Chingu Kim, Hyung‐Chul Pae, Jung‐Seok Lee, Ui‐Won Jung, Seong‐Ho Choi
SJR Q1Journal of Periodontal & Implant ScienceOA

BCP can achieve proper dimensional stability with minimal reduction of the graft height in a 3- to 6-year healing period after maxillary sinus augmentation. The healing period and the amount of graft material influenced the resorption of BCP.

Oral SurgeryDentistry
14
논문|인용수 22·2011
Case series of maxillary sinus augmentation with biphasic calcium phosphate: a clinical and radiographic study
차재국, 박정철, 정의원, 김창성, 조규성, 최성호

Purpose: The aim of this study was to evaluate 3.5 years-cumulative survival rate of implants placed on augmented sinus using Osteon, a bone graft material, and to assess the height of the grafted material through radiographic evaluation. Methods: Twenty patients were treated with maxillary sinus augmentation and 45 implant fixtures were installed simultaneously or after 6 months healing period. The height of the augmented sinus and the loss of marginal bone were measured by panoramic and intrao

15
논문|인용수 18·2018
Osteogenic efficacy of BMP‐2 mixed with hydrogel and bone substitute in peri‐implant dehiscence defects in dogs: 16 weeks of healing
Jae‐Kook Cha, Ui‐Won Jung, Daniel S. Thoma, Christoph H. F. Hämmerle, Ronald E. Jung
SJR Q1Clinical Oral Implants ResearchOA

Abstract Objectives The objective of this study was to determine the effect of bone morphogenetic protein‐2 ( BMP ‐2) mixed with either polyethylene glycol hydrogel or synthetic bone substitute ( SBS ) on new bone formation in peri‐implant dehiscence defects after 16 weeks of healing. Materials and methods A guided bone regeneration procedure was performed in box‐type peri‐implant defects that were surgically prepared in six beagle dogs. The following four experimental groups were used (i) contr

Biomedical EngineeringEngineering

대표 연구 분야

Oral SurgeryUrologyBiomedical EngineeringPeriodonticsOrthodonticsMolecular Biology

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