강재헌 교수
Jae-Hun Kang
성균관대학교 의학과 · 의학
연구실 소개
강재헌 교수의 연구실은 비만 및 대사질환과 관련된 경제적 부담과 생리학적 기전을 중심으로 연구를 진행하고 있습니다. 특히 과체중 및 비만이 고혈압, 당뇨병, 이상지질혈증 등 주요 만성질환에 미치는 기여도를 정량적으로 분석하며, 이를 바탕으로 예방 정책의 근거를 마련하고자 합니다. 또한 천연식물 성분을 활용한 체지방 감소제제의 유효성과 안전성에 대한 임상 연구를 통해 비만 관리의 새로운 전략을 모색하고 있습니다. 특히 혈관 생성 억제를 통한 복부 비만 개선 메커니즘에 대한 기초 및 임상 연구도 함께 진행되고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15This study was conducted to estimate the socioeconomic costs of overweight and obesity in a sample of Korean adults aged 20 yr and older in 2005. The socioeconomic costs of overweight and obesity include direct costs (inpatient care, outpatient care and medication) and indirect costs (loss of productivity due to premature deaths and inpatient care, time costs, traffic costs and nursing fees). Hypertension, diabetes mellitus, dyslipidemia, ischemic heart disease, stroke, colon cancer and osteoart
Previous studies have reported a relationship between short sleep duration and childhood overweight. Although school-aged children tend to compensate for weekday sleep deficit by increasing weekend sleep duration, the association between weekend catch-up sleep and childhood overweight remains unclear. This study aimed to examine the relationship between weekend catch-up sleep and being overweight in children. A total of 936 school children (48.2% boys) aged 10 or 11 years participated in this sc
BACKGROUND: YY-312 is a herbal extract powder from Imperata cylindrica Beauvois, Citrus unshiu Markovich, and Evodia officinalis Dode, which have health promoting effects, including body fat reduction. We aimed to evaluate the efficacy and safety of YY-312 for body fat reduction in overweight adults. METHODS: . The daily dose of YY-312 was 2400 mg (containing 1800 mg of active herbal extract and 600 mg of cyclodextrin). Primary outcomes were reductions in body fat mass (BFM) and body fat percent
CONTEXT: The association of menstrual cycle length and irregularity with the risk of non-alcoholic fatty liver disease (NAFLD) is unknown. OBJECTIVE: We examined this association in large cross-sectional and cohort studies. METHODS: The cross-sectional study included 72 092 women younger than 40 years who underwent routine health examinations; the longitudinal analysis included the subset of 51 118 women without NAFLD at baseline. Long or irregular cycles were defined as menstrual cycles of 40 d
이 연구는 고혈압, 당뇨병, 이상지질혈증으로 지출된 진료비 중 과체중 및 비만의 기여분을 추계하기 위한 질병비용연구로서 국민건강보험공단의 건강검진 및 건강보험급여 자료를 활용한 연구이다. 연구결과 2005년 현재 고혈압, 당뇨병, 이상지질혈증 때문에 지출된 총 진료비 중 과체중 및 비만의 기여분은 각각 4,561억원(4,328억원-4,805억원), 2,823억원(2,487억원-3,176억원), 165억원(147억원-183억원)이었고, 이를 모두 합하면 7,549억원(6,961억원-8,164억원)이었다. 이는 해당 연도의 고혈압 총 진료비의 34.6%(32.9%-36.5%), 당뇨병 총 진료비의 32.5%(28.6%-36.6%), 이상지질혈증 총 진료비의 19.4%(17.3%-21.6%)를 차지한다. 또한 이 세 가지 질병의 총 진료비를 기준으로 했을 때 과체중 및 비만이 기여한 금액은 33.3%(30.7%-36.0%)에 해당하였다. 이는 과체중과 비만을 예방한다면 고혈압, 당뇨병,
Adipose tissue growth is angiogenesis‐dependent, and angiogenesis inhibitors can regulate adipose tissue mass by cutting off the blood supply. We examined whether antiangiogenic herbal composition Ob‐X can reduce fast‐growing abdominal fat, especially visceral fat in humans by inhibiting angiogenesis. Eighty abdominally obese subjects (body mass index: 25‐29.9 kg/m 2 , waist circumference: exceeding 90 cm for males and 85 cm for females) participated in a 12‐week randomized, double‐blind, placeb
xercise prescription for obese patients should be individualized since they are not accustomed to exercise. When we prescribe exercise for obese patients, low impact exercises such as walking, cycling, swimming are recommended.
Background: Over the last decade, the male obesity rate in Korea has surged from 36.3% in 2012 to 46.3% in 2021. The proportion of overweight and obese students among elementary, middle, and high school students increased from 22.9% in 2016 to 30.8% in 2021.Current Concepts: Various methods, such as body mass index, waist circumference measurement, and impedance body fat analysis, are used to diagnose obesity. Obesity treatment is needed to establish an individualized treatment plan based on the
Background: Primary healthcare is a cornerstone of the healthcare system, playing a vital role in addressing individual healthcare needs, and organizing and strengthening the national healthcare system. Owing to the rapid growth in healthcare demand and the treatment-focused approach, primary healthcare may face challenges in providing preventive healthcare.Current Concepts: Disease prevention measures in primary healthcare including health education, nutrition counseling, and immunization have
Background Hypertension and diabetes are typically managed in primary care settings, where continuous and tailored care based on continuity in daily life is essential to improve health outcomes. Objective To address the shortage of human and material resources in primary care and to enhance health outcomes, we developed and implemented a comprehensive digital medicine platform in a real-world setting. Methods A patient application (app) and a web app for healthcare providers were developed to en
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