조재화 교수
Jae Hwa Cho
연세대학교 내과 · 의학
연구실 소개
조재화 교수의 연구실은 폐질환 분야에서 임상적 및 기초적 연구를 융합적으로 수행하고 있습니다. 주요 연구 방향은 기저성 폐질환을 동반한 기흉, 간질성 폐질환, 흉막염 및 폐암과 같은 폐의 복합적 질환의 병태생리학적 기전과 임상 관리 전략을 규명하는 데 초점이 맞춰져 있습니다. 특히, 유전적 변이와 면역 반응의 상관관계를 분석함으로써 개인 맞춤형 폐질환 진단 및 치료 전략 개발을 목표로 하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Pneumothorax-either spontaneous or iatrogenic-is commonly encountered in pulmonary medicine. While secondary pneumothorax is caused by an underlying pulmonary disease, the spontaneous type occurs in healthy individuals without obvious cause. The British Thoracic Society (BTS, 2010) and the American College of Chest Physicians (ACCP, 2001) published the guidelines for pneumothorax management. This review compares the diagnostic and management recommendations between the two societies. Patients di
BACKGROUND: Connective tissue disease associated with interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD) alone have same pathological and imaging backgrounds. However, the differences between lung cancer development and the mortality risk between these two conditions are unclear. Incidence of primary lung cancer and all-cause mortality were studied between interstitial lung disease patients with and without connective tissue disease. METHODS: Data were extracted from the Kor
In order to examine the correlation of p53 mutation with heterogeneous histological differentiation and invasiveness of gastric carcinoma, we analyzed 46 areas (three to six per case) that were different histologically and anatomically in 12 advanced gastric carcinomas, shown previously to be positive for p53 mutation, using immunohistochemical, polymerase chain reaction-single strand conformation polymorphism, and direct DNA sequencing analyses. DNA derived from different sites in nine cases ha
Patients with acute pulmonary embolism (PE) were identified retrospectively from patients hospitalized during a 2-year period from 2005 to 2007. Among adult patients (≥20 years), the incidence of established acute PE was 88 (0.17%) of 50 882 in Dongsan Hospital. The incidence of acute PE at Dongsan Hospital was 26% lower than that at Henry Ford Hospital (P < .01). Among patients more than 50 years of age, PE was more frequent in women (0.32%; 95% CI, 0.24-0.4) than in men (0.15%; 95% CI, 0.1-0.2
BACKGROUND: Tuberculous pleural effusion (TPE) is one of the most common forms of extrapulmonary tuberculosis. Because most studies of TPE focused on the pleural space, little information regarding lung parenchyma is available. We therefore aimed to investigate immune responses in the lung parenchyma of TPE patients without pulmonary tuberculosis. METHODS: Patients with any evidence of pulmonary tuberculosis, either from radiologic or bacteriologic evaluation, were excluded. Bronchoalveolar lava
BACKGROUNDDuring 2009 pandemic period, many Koreans were infected and admitted with Influenza A/H1N1. The primary aim of this study was to evaluate whether the structures of an intensive care unit (ICU) were associated with the outcomes of critically ill patients.METHODSThis retrospective observational study examined critically ill adult patients with influenza A/H1N1, who were admitted to 24 hospitals in Korea, from September 2009 to February 2010. We collected data of ICU structure, patients a
참나무시들음병 매개충인 광릉긴나무좀 (Platypus koryoensis (Murayama)) (Coleoptera: Platypodidae) 모니터링에 활용 가능한 트랩 종류, 색, 설치위치가 포획수에 미치는 영향이 조사되었다. 조사는 경기도 파주시 광탄면에서 수행되었으며 끈끈이 평판 트랩과 다중깔때기 트랩 두 종류 트랩이 이용되었다. 조사된 두 트랩의 종류는 광릉긴나무좀 포획수에 영향을 미치지 않았다. 끈끈이 평판 트랩의 경우 노란색, 검정색, 흰색, 투명색으로 시험한 결과 트랩색이 광릉긴나무좀 포획효율에 영향을 미치지 않았다. 끈끈이 평판 트랩과 다중깔때기 트랩 모두 수간내 경사 위쪽과 아래쪽에 설치된 경우, 산의 경사 위쪽에 설치한 트랩에 유의하게 많은 수의 광릉긴나무좀이 포획되었다. 이는 두 가지 트랩이 모두 광릉긴나무좀 모니터링 및 방제에 효율적으로 활용될 수 있음을 보여주는 것이다. Differences in the number of Platypus koryoensis
BACKGROUND: Chronic cough is a common symptom that requires the systematic diagnostic approach for proper evaluation. Postnasal drip syndrome(PNDS), bronchial asthma, gastroesophageal reflux disease(GERD), and chronic bronchitis are among the common causes. This study was conducted to evaluate the spectrum and the frequency of the causes of chronic cough. METHODS: We prospectively evaluated 93 patients who had chronic cough despite normal chest radiographic finding. History and physical examinat
We report a pulmonary infarction in 68-year-old man who was referred for an asymptomatic pulmonary nodule in chest radiography. Computed tomography (CT), positron emission tomography (PET), and transthoracic needle aspiration suggested suspicion for malignancy. Video-assisted thoracoscopic surgery (VATS) was performed for histologic diagnosis. Our case is a pulmonary nodule due to pulmonary infarction diagnosed by VATS in Korea.
Purpose: Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with considerable morbidity and mortality. Its incidence after pulmonary embolism and associated risk factors in the Korean population are not well documented. Methods: A retrospective cohort study was conducted to assess the incidence of symptomatic CTEPH in patients with an acute episode of pulmonary embolism without prior history of venous thromboembolism. Patients experiencing unexplained persistent dyspnea during f
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