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심재항 교수

Jae-Hyang Shim

한양대학교 마취통증의학과 · 의학

연구실 소개

심재항 교수의 연구실은 만성 통증, 특히 신경성 통증과 이차성 통증의 메커니즘과 치료 전략에 중점을 두고 있습니다. 초음파 유도 신경차단, 척수 자극술 등 정밀하고 비침습적인 통증 치료 기법의 임상적 적용과 기전 연구를 진행하고 있으며, 특히 GON 블록의 해부학적 기초 자료 확보와 통증 완화 효과 분석에 기여하고 있습니다. 또한, 알파2-디elta 리간드 작용을 기반으로 한 약물(예: 프리가바린)의 통증 조절 메커니즘에 대한 분자생물학적 연구도 함께 수행하고 있습니다.

만성통증초음파유도차단척수자극술GON블록알파2-디elta리간드

연구 현황

논문 수
97
총 인용 수
299
최근 5년 논문
13
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
13총합
2016
2017
2019
2020
2023
5개년 연도별 피인용 수
55총합
20162017201920202023

주요 논문

15
1
논문|인용수 67·2011
Ultrasound-guided greater occipital nerve block for patients with occipital headache and short term follow up
Jae Hang Shim, So Young Ko, Mi Rang Bang, Woo Jae Jeon, Sang Yun Cho, Jong Hoon Yeom, Woo Jong Shin, Kyoung Hun Kim, Jae-Chol Shim
SJR Q1Korean journal of anesthesiologyOA

BACKGROUND: The greater occipital nerve (GON) block has been frequently used for different types of headache, but performed with rough estimates of anatomic landmarks. Our study presents the values of the anatomic parameters and estimates the effectiveness of the ultrasound-guided GON blockade. METHODS: The GON was detected using ultrasound technique and distance from external occipital protuberance (EOP) to GON, from GON to occipital artery and depth from skin to GON was measured in volunteers.

SurgeryMedicine
2
논문|인용수 15·2020
Multimodal analgesia or balanced analgesia: the better choice?
Jae Hang Shim
SJR Q1Korean journal of anesthesiologyOA

The concept of balanced anesthesia was introduced by John S. Lundy in 1926 He suggested that a balanced application of different agents and techniques could produce the different components of anesthesia such as amnesia, analgesia, motor paralysis, and abolition of autonomic reflexes. Induction of anesthesia with a single agent alone can cause several complications. On the other hand, using a combination of more than one anesthetic drugs and techniques can improve patient safety, reduce the side

SurgeryMedicine
3
논문|인용수 6·2010
Polyostotic rib fibrous dysplasia resected by video-assisted thoracoscopic surgery with preservation of the overlying periosteum
Jae Hang Shim, Soon‐Ho Chon, Chul Burm Lee, Jeong Heo
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
RheumatologyMedicine
4
논문|인용수 4·2011
Clinical Application of α2-δ Ligand
Jae Hang Shim
Hanyang Medical ReviewsOA

Chronic pathological pain is sustained by mechanisms of peripheral and central sensitization, which are being increasingly investigated at the molecular and cellular levels. The molecular mechanisms of sensitization that occur in peripheral nociceptors and the dorsal horns of the spinal cord are putative targets for context-dependent drugs. Pregabalin and gabapentin are analogs of the neurotransmitter gamma-aminobutyric acid (GABA). They are alpha2-delta ligands that have analgesic, anticonvulsa

PhysiologyMedicine
5
논문|인용수 4·2015
Limitations of spinal cord stimulation for pain management
Jae Hang Shim
SJR Q1Korean journal of anesthesiologyOA

As mentioned before [1], the spinal cord stimulation is very useful treatment modality for intractable pain. The spinal cord stimulator (SCS) has been applied for the treatment of pain associated with many different disease entities, including intractable pain, headache, and angina pain. It has also been applied for non-pain-related conditions such as congestive heart failure, ischemic peripheral vascular disease, interstitial cystitis, intractable spasticity, and cerebral vasospasm after subara

Anesthesiology and Pain MedicineMedicine
6
editorial|인용수 3·2017
Is ultrasound-guided procedure entirely reliable?
Jae Hang Shim
SJR Q1Korean journal of anesthesiologyOA
SurgeryMedicine
7
논문|인용수 3·2013
Is Fluoroscopy-guided Suprascapular Nerve Block Better Than Other Techniques?
Jae Hang Shim
SJR Q1The Korean journal of painOA

Received November 15, 2012. Accepted November 16, 2012. Correspondence to: Jae Hang Shim, MD Department of Anesthesiology and Pain Medicine, School of Medicine, Hanyang University, 249-1 Kyomun-dong, Guri 471-701, Korea Tel: +82-31-560-2390, Fax: +82-31-563-1731, E-mail: jhshim@hanyang.ac.kr This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commerc

SurgeryMedicine
8
논문|인용수 3·2013
Spinal cord stimulation: panacea for incurable diseases?
Jae Hang Shim
SJR Q1Korean journal of anesthesiologyOA

A spinal cord stimulator is usually used as an electro-modulator for pain treatment. Shealy et al. [1] first reported the use of a spinal cord stimulator in an elderly male suffering with terminal bronchogenic carcinoma and right-sided chest pain in 1967. Since then, spinal cord stimulation (SCS) has been applied to many disease entities, such as neuropathic pain, failed back surgery syndrome, complex regional pain syndrome, and ischemic peripheral vascular disease [2-4]. The indications for SCS

Anesthesiology and Pain MedicineMedicine
9
논문|인용수 2·2011
Is it necessary to use prophylactics for preventing PONV?
Jae Hang Shim
SJR Q1Korean journal of anesthesiologyOA

Postoperative nausea and vomiting (PONV) are common and distressing postsurgical symptoms [1] which continue to be a significant concern for anesthesiologists. PONV occurs in 20% to 30% of the general population underwent surgery and in up to 70% to 80% of high risk patients [2,3]. PONV is a complex physiologic phenomenon involving multiple neurophysiologic pathways with both central and peripheral receptor mechanisms. A variety of factors have been associated with an increased incidence of p

SurgeryMedicine
10
논문|인용수 2·2011
Ultrasound-guided greater occipital nerve block for patients with occipital headache and short term follow up
심재항, 고소영, 방미랑, 전우재, 조상윤, 염종훈, 신우종, 김경헌, 심재철

Background: The greater occipital nerve (GON) block has been frequently used for different types of headache, but performed with rough estimates of anatomic landmarks. Our study presents the values of the anatomic parameters and estimates the effectiveness of the ultrasound-guided GON blockade. Methods: The GON was detected using ultrasound technique and distance from external occipital protuberance (EOP) to GON, from GON to occipital artery and depth from skin to GON was measured in volunteers.

11
논문|인용수 2·2016
Comparison of the GlideScope and the McGrath method using vascular forceps and a tube exchanger in cases of simulated difficult airway intubation
심재항, 전우재, 조상윤, 최규호

Background: A “difficult airway” can be simulated with an extrication collar, which restricts cervical motion and mouth opening. The purpose of this study is to compare the efficacy of the GlideScope and the McGrath in difficult airway simulation. Methods: Patients were randomized using computer-generated numbers and were placed into the GlideScope group or the McGrath group. The total intubation time was defined as the time measured from when the anesthesiologist picks up the device to the time

12
논문|인용수 2·2005
슬관절 치환술을 시행하는 환자에서 경막외 선행진통이 술 후 통증에 미치는 영향에 대한 평가
심재항, 염종훈

Background: Postoperative pain management is critical for optimal care of orthopedic surgical patients. Preemptive analgesia such as neuraxial blocks and methods of drug delivery system such as infusion pumps may be used after total knee arthroplasty. The aim of this study was to examine the analgesic and pre-emptive effect of continuous epidural block initiated before total knee arthroplasty upon postoperative period. Methods: A double-blind randomized study was performed in thirty-nine patien

13
논문|인용수 1·2002
The Analgesic Interactions Among Intrathecal Morphine, Ketorolac and L-NAME on Formalin-induced Pain in Rats
Jae Hang Shim, Jong Hun Jun, Kyoung Hun Kim, Jong Hun Yeom, Jung Kook Suh
SJR Q1Korean Journal of AnesthesiologyOA

Background: Morphine has a direct action on morphine receptors in the brain and spinal cord.Intrathecally administered L-NAME, a nitric oxide synthase inhibitor, is known to have an antinociceptive effect on formalin-induced pain in animal studies.Efficacy of intrathecally administered ketorolac, a cyclooxygenase inhibitor, is somewhat controversial.The interactions of intrathecally administered morphine, ketorolac and L-NAME on formalin-induced nociception was studied.Methods: Male Sprague-Dawl

PhysiologyMedicine

대표 연구 분야

SurgeryAnesthesiology and Pain MedicinePhysiologyCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineMolecular Biology

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