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이재우 교수

Jae-woo Lee

고려대학교 약학과 · 의학

연구실 소개

이재우 교수의 연구실은 만성질환 예방과 개인화된 건강관리를 목표로 하며, 특히 뇌졸중, 심혈관질환, 인지기능 저하와 같은 주요 질환의 위험도를 정량적으로 평가하고, 이를 기반으로 개인 맞춤형 예방 메시지와 생활습관 개선 전략을 개발하고 있습니다. 대규모 건강검진 데이터와 국가 건강보험 데이터를 기반으로 한 장기 추적 연구를 중심으로, 약물 사용(예: 스타틴), 흡연(전자담배 포함), 음주 습관 변화 등 생활요인과 질병 간의 인과관계를 분석하고 있습니다. 특히 고령화 사회에서의 혈압 변화 패atters와 맥동압의 역할에 대한 기초 연구도 진행 중입니다.

뇌졸중 위험도스마트 건강관리장기 추적 연구생활습관 개선심혈관질환 예방

연구 현황

논문 수
149
총 인용 수
1,509
최근 5년 논문
25
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
25총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
115총합
20222023202420252026

주요 논문

15
1
논문|인용수 75·2014
Serum and ultrastructure responses of common carp (Cyprinus carpio L.) during long-term exposure to zinc oxide nanoparticles
Jae‐woo Lee, Ji‐Eun Kim, Yujin Shin, Jisung Ryu, Ig‐Chun Eom, Jung Sick Lee, Younghun Kim, Pilje Kim, Kyunghee Choi, Byoung-cheun Lee
SJR Q1Ecotoxicology and Environmental Safety
Health, Toxicology and MutagenesisEnvironmental Science
2
논문|인용수 50·2017
The development and implementation of stroke risk prediction model in National Health Insurance Service's personal health record
Jae‐woo Lee, Hyunsun Lim, Dong Wook Kim, Soon‐Ae Shin, Jinkwon Kim, Bora Yoo, Kyung-hee Cho
SJR Q1Computer Methods and Programs in BiomedicineOA

This study developed the stroke risk prediction model and the personalized warning and the lifestyle correction message based on the national health examination data and uploaded them to the personal health record service called My Health Bank in the health information website - Health iN. By doing so, it urged medical users to strengthen the motivation of health management and induced changes in their health behaviors.

Public Health, Environmental and Occupational HealthMedicine
3
논문|인용수 43·2020
Statin exposure and the risk of dementia in individuals with hypercholesterolaemia
Jae‐woo Lee, Eun-A Choi, Yoon‐Seob Kim, Y. Kim, Hyo‐Sun You, Ye-Eun Han, H.‐S. Kim, Yoon‐Jong Bae, Ji Hyoun Kim, Hee‐Taik Kang
SJR Q1Journal of Internal MedicineOA

OBJECTIVES: This study aimed to examine the association between statin exposure and dementia risk in individuals with hypercholesterolaemia using data from the NHIS-HEALS database between 2002 and 2015. METHODS: Subjects were classified into statin exposure and statin nonexposure groups according to medication possession ratio. Dementia was defined as those with primary diagnostic dementia codes such as F00-F03, G30, G31.1, G31.9 or G31.82. Cox proportional hazards regression models were adopted

SurgeryMedicine
4
논문|인용수 31·2018
Trends in diabetes prevalence among Korean adults based on Korean National Health and Nutrition Examination Surveys III–VI
Jae‐woo Lee, Hee‐Taik Kang, Hyoung-Ji Lim, Byoungjin Park
SJR Q1Diabetes Research and Clinical PracticeOA
Nutrition and DieteticsNursing
5
논문|인용수 30·2019
Cigarette Smoking in Men and Women and Electronic Cigarette Smoking in Men are Associated with Higher Risk of Elevated Cadmium Level in the Blood
Jae‐woo Lee, Ye-Seul Kim, Yonghwan Kim, Hyo-Sun Yoo, Hee‐Taik Kang
SJR Q2Journal of Korean Medical ScienceOA

We investigated the association between blood concentration of cadmium and smoking status including use of electronic cigarettes (E-cigars). Methods: We used data from the Korea National Health and Nutritional Survey 2013 and 2016. A total of 4,744 participants (2,162 men and 2,582 women) were included and were categorized into five groups (Non-smokers, E-cigar non-users in past-smokers, E-cigar users in pastsmokers, E-cigar non-users in cigarette-smokers and E-cigar users in cigarette-smokers).

Health, Toxicology and MutagenesisEnvironmental Science
6
논문|인용수 30·2019
Statin use and site-specific risk of colorectal cancer in individuals with hypercholesterolemia from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS)
Jae‐woo Lee, Na-Young You, Ye-Seul Kim, Yonghwan Kim, Joungyoun Kim, Hee‐Taik Kang
SJR Q1Nutrition Metabolism and Cardiovascular Diseases
Cancer ResearchBiochemistry, Genetics and Molecular Biology
7
논문|인용수 23·2020
Metformin usage and the risk of colorectal cancer: a national cohort study
Jae‐woo Lee, Eun-A Choi, Ye-Seul Kim, Yonghwan Kim, Hyo‐Sun You, Ye-Eun Han, Hyeong-Seop Kim, Yoon‐Jong Bae, Joungyoun Kim, Hee‐Taik Kang
SJR Q2International Journal of Colorectal Disease
Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 20·2024
Reduced Alcohol Consumption and Major Adverse Cardiovascular Events Among Individuals With Previously High Alcohol Consumption
Dong Oh Kang, Dae In Lee, Seung‐Young Roh, Jin Oh Na, Cheol Ung Choi, Jin Won Kim, Eung Ju Kim, Seung‐Woon Rha, Chang Gyu Park, Ye-Seul Kim, Yonghwan Kim, Hyo‐Sun You
SJR Q1JAMA Network OpenOA

Importance: Cardiovascular benefits of mild to moderate alcohol consumption need to be validated in the context of behavioral changes. The benefits of reduced alcohol consumption among people who drink heavily across different subtypes of cardiovascular disease (CVD) are unclear. Objective: To investigate the association between reduced alcohol consumption and risk of major adverse cardiovascular events (MACEs) in individuals who drink heavily across different CVD subtypes. Design, Setting, and

Pathology and Forensic MedicineMedicine
9
논문|인용수 18·2023
Changes in alcohol consumption habits and risk of atrial fibrillation: a nationwide population-based study
Jae‐woo Lee, Seung‐Young Roh, Woong-Su Yoon, Jinseob Kim, Eunseo Jo, Dae‐Hwan Bae, Min Kim, Ju‐Hee Lee, Sang Min Kim, Woong Choi, Jang‐Whan Bae, Kyung‐Kuk Hwang
SJR Q1European Journal of Preventive CardiologyOA

AIMS: Heavy alcohol consumption is an established risk factor for atrial fibrillation (AF). However, the association between habitual changes in heavy habitual drinkers and incident AF remains unclear. The aim of this study was to evaluate whether absolute abstinence or reduced drinking decreases incident AF in heavy habitual drinkers. METHODS AND RESULTS: Atrial fibrillation-free participants with heavy alcohol consumption registered in the Korean National Health Insurance Service database betw

Pathology and Forensic MedicineMedicine
10
논문|인용수 13·2002
Pulse Pressure and Systolic Blood Pressure
Jae‐woo Lee
Sunhwan'gi

According to the results of the latest Framingham Heart Study, with increasing age, there is a gradual shift from diastolic blood pressure (DBP to systolic blood pressure (SBP and then finally to pulse pressure (PP as predictors of coronary heart disease (CHD risk. After age 60, DBP was negatively related to CHD risk and PP became superior to SBP as a predictor. A hallmark of the aging process is vascular wall thickening, which is more marked in the central elastic arteries than in the periphera

Cardiology and Cardiovascular MedicineMedicine
11
논문|인용수 10·2017
Trends in socioeconomic costs of morbid obesity among Korean adults, 2009–2013: Data from National Health Insurance Service
Jae‐woo Lee, Young Eun Choi, Dong Wook Kim, Sun‐Mi Lee, Kyung‐Hee Cho
SJR Q2Obesity Research & Clinical Practice
General Health ProfessionsHealth Professions
12
논문|인용수 8·2022
Exposure to Secondhand Smoke and a Tobacco-Specific Carcinogen in Non-Smokers
Jae‐woo Lee, Woojung Yang, Ye-Seul Kim, Yonghwan Kim, Hyo-Sun Yoo, Hee‐Taik Kang
SJR Q2Korean Journal of Family MedicineOA

BACKGROUND: The International Agency for Research on Cancer classifies 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) as a known carcinogen. This study aimed to investigate the association between exposure to secondhand smoke (SHS) and NNAL concentrations in non-smokers. METHODS: This was a cross-sectional study based on data from the 2016 to 2018 Korea National Health and Nutrition Examination Survey. Urine NNAL concentrations were categorized into tertiles of 3,615 study participants who

PhysiologyMedicine
13
논문|인용수 7·2023
Comparison of a Tobacco-Specific Carcinogen in Tobacco Cigarette, Electronic Cigarette, and Dual Users
Jae‐woo Lee, Sukil Kim
SJR Q2Journal of Korean Medical ScienceOA

Background: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is known as a lung carcinogen.The objective of this study was to investigate associations of urine NNAL concentrations and smoking status.Methods: This was a cross-sectionally designed study based on data from the 2016-2018 Korean National Health and Nutrition Examination Survey.A total of 2,845 participants were classified into past-smoker, electronic cigarette (e-cigar) only, dual-user, and cigarette only smoker groups.All sampli

PhysiologyMedicine
14
논문|인용수 7·2017
Tumor Marker Kinetics as Prognosticators in Patients with Unresectable Gallbladder Adenocarcinoma Undergoing Palliative Chemotherapy
Jae‐woo Lee, Yong‐Tae Kim, Sang Hyub Lee, Jun Hyuk Son, Jin Woo Kang, Ji Kon Ryu, Dong Kee Jang, Woo Hyun Paik, Ban Seok Lee
SJR Q1Gut and LiverOA

CA 19-9 kinetics was a reliable prognosticator of PFS and OS in patients with unresectable GBC who underwent palliative chemotherapy.

SurgeryMedicine
15
논문|인용수 5·2024
Higher high-density lipoprotein cholesterol levels increased vertebral osteoporotic fracture, but reduced hip fracture in men based on the National Health Insurance Service-National Health Screening Cohort
Jae‐woo Lee, Jeong‐Sook Kim, Yonghwan Kim, Ye-Seul Kim, Joungyoun Kim, Hee‐Taik Kang
SJR Q1The Spine Journal
Orthopedics and Sports MedicineMedicine

대표 연구 분야

Cardiology and Cardiovascular MedicineSurgeryPhysiologyNutrition and DieteticsCancer ResearchPublic Health, Environmental and Occupational Health

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