오재령 교수
Jae-Young Oh
고려대학교 안과 · 의학
연구실 소개
오재령 교수의 연구실은 망막 및 복합혈관성 망막질환의 생체영상 기반 정량적 분석을 핵심으로 하며, 특히 산소공급 이상과 혈관 변화가 연관된 황반변성 및 중앙결막부종의 병태생리적 기전을 광학단층촬영(ОСТ) 및 혈관단층촬영(ОСТA)을 통해 규명하고 있습니다. 특히 시신경세포층 두께, 망막외층 손상, 망막혈관 밀도 및 망막하모세포 혈관지수 등 정량적 지표를 기반으로 시력과의 상관관계를 분석함으로써 조기 진단 및 개인 맞춤형 치료 전략 수립에 기여하고자 합니다. 최근에는 혈류순환 이상이 망막질환의 초기 단계에서 나타날 수 있음을 밝혀내며, 혈관성 기전의 중요성을 강조하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The choroid was thicker in eyes with polypoidal choroidal vasculopathy or central serous chorioretinopathy than in control or age-related maculopathy groups.
BCVA after MHS correlates with objectively ascertainable SD-OCT measurements of IS/OS defects and other features. The postoperative area of the IS/OS defect, when directly measured, correlates more strongly with BCVA than do linear-based measurements, perhaps because of the irregular shape of the IS/OS defect after surgery.
In addition to vascular insufficiency in the choroid or choriocapillaris, retinal vascular alteration was apparent in eyes with early AMD. It may suggest that retinal vessels were involved in the pathogenesis of AMD even while changes in nonvascular components of the retina were not yet apparent.
Purpose: To quantify vascular and structural macular variables in healthy eyes and to investigate correlations between these variables and age using optical coherence tomography angiography. Materials and methods: A total of 261 eyes of 261 subjects with normal fundus were included. Central macular thickness, ganglion cell layer to inner plexiform layer thickness, outer retina layer thickness, subfoveal choroidal thickness, and choroidal vascularity index were measured using optical coherence to
The visual function of eyes with resolved central serous chorioretinopathy was suboptimal and was better explained when various parameters showing retinal status were combined and interpreted together.
Purpose: The purpose of this study was to investigate the relationship between the ocular perfusion pressure (OPP) and subfoveal choroidal thickness (CT) in eyes with early age-related macular degeneration (AMD) with or without reticular pseudodrusen (RPD). Methods: We evaluated the clinical history, blood pressure parameters, fundus photography, and optical coherence tomography images of consecutive patients with early AMD. We calculated the mean OPP from blood pressure and intraocular pressure
Transient hypotony frequently developed after silicone oil removal, and most cases recovered within 1 week postoperatively. Patients with a long axial length had increased odds of developing transient hypotony after silicone oil removal.
Chronic MH has features distinct from those of acute symptomatic MH on optical coherence tomography. These findings provide useful insight for the differentiation of chronic MH from acute MH.
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