박재범 교수

BACKGROUND: Duct-to-duct (DD) anastomosis is an accepted procedure for biliary reconstruction in living donor liver transplantation (LDLT). However, biliary complication rates in LDLT recipients have been reported to be as high as 20% to 30% or more. In this study, we examined various potential risk factors for biliary stricture (BS) that occurs in the context of DD reconstruction in a single-active transplant center. METHODS: Enrolled in this study were adults who underwent their first LDLT wit

In patients with symptomatic P-AVM, surgical resection of the affected pancreas showed a successful result. When a patient is at a high risk for surgical treatment, transjugular intrahepatic portosystemic shunt, transarterial embolization, and radiation therapy might be other treatment options.

To evaluate the effects of intermittent hepatic inflow occlusion (IHIO) during donor hepatectomy for living donor liver transplantation (LDLT) in recipients and donors, we performed a single-center, open-label, prospective, parallel, randomized controlled study. Adult donor-recipient pairs undergoing LDLT with right hemiliver grafts were randomized into IHIO and control groups (1:1). In the IHIO group, IHIO was performed during donor hepatectomy. The primary endpoint was the peak serum alanine a

BACKGROUND: Tolerance induction is an important goal in the field of organ transplantation. We have sequentially modified our conditioning regimen for induction of donor-specific tolerance in recipients of major histocompatibility complex-mismatched combined kidney and bone marrow transplantation (CKBMT). METHODS: From December 2011 to May 2017, 8 major histocompatibility complex-mismatched patients received CKBMT. The initial conditioning regimen (protocol 1) consisted of cyclophosphamide (CP),

This prospective study was designed to investigate the clinically significant level of parvovirus B19 viral load using quantitative real-time (RT) polymerase-chain reaction (PCR) in kidney transplantation (KT) recipients. One hundred forty-three adult recipients who underwent their first KT between November 2003 and October 2005 were enrolled. Six blood samples (the first taken preoperatively, subsequent samples taken every 4 weeks for 20 weeks) were taken from each patient for parvovirus B19 DN

The principal objective of this study was to evaluate the feasibility of Hepatitis B virus (HBV) vaccine switch program after 1-year Hepatitis B immunoglobulin (HBIG) for the prevention of de novo HBV (DNHBV) infection in pediatric recipients of hepatitis B core antibody (anti-HBc)-positive grafts. In this study, we enrolled pediatric recipients (n = 14), who had undergone living donor liver transplantation with anti-HBc-positive grafts between July 2000 and July 2005 and were followed up for ov

PURPOSE: Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of DKT with those of single kidney transplantation from standard criteria donors (SCDs) and ECDs. METHODS: In 2014, we began performing DKT using both kidneys from deceased donors greater than 70 years of age with one of two risk factors: serum creatinine (sCr) level over 3.0 mg/dl or eGFR under 30 ml/min. By 2017, we had performed 15 DKTs. We

The objective of this study was to compare outcomes between basiliximab and low-dose r-ATG in living donor kidney transplantation recipients with low immunological risk. Patients in the low-dose r-ATG group received 1.5 mg/kg of r-ATG for 3 days (total 4.5 mg/kg). Graft survival, patient survival, acute rejection, de novo donor specific antibody (DSA), estimated glomerular filtration rate (e-GFR) changes, and infection status were compared. Among 268 patients, 37 received r-ATG, and 231 received

본 연구는 특수학교 교사의 교직생활을 중심으로 기술함으로써 특수학교 교사가 수행하는 수업활동, 학교생활지도, 업무가 어떻게 진행되는지 참여관찰을 통해 특수학교 교직문화의 특성을 밝히는데 목적을 갖는다. 이를 위해 서울특별시 사립특수학교 한곳을 선정하여 9개월 동안 중등부 담당교사 3명의 교직생활을 중심으로 참여관찰 하였다. 특수학교 교사의 교직생활은 크게 수업활동, 학교생활지도, 업무로 나누어진다. 수업활동은 ‘개인차 및 안전사고 예방을 고려한 수업하기’, 학교생활지도는 ‘정확히 인식하고 철저히 점검하기’, ‘쉬는 시간에도 반복적으로 연습시키기’, ‘교육의 일환으로 식사지도하기’, ‘꼼꼼히 재확인하기’, 업무는 ‘분주함 속에서도 자투리시간 이용하기’, ‘공적인 일하기’, ‘마무리 작업하기’로 나타났다. 이 연구결과는 일반학교에 나타나는 특성과 다른 특수학교 교직문화의 독특한 특성으로 보인다. 이러한 연구결과를 기초로 하여 특수학교 교직문화에 대한 후속연구를 제시하였다.

Xenotransplantation using pigs' liver offers a potentially alternative method to overcome worldwide donor shortage, or more importantly as a bridge to allotransplantation. However, it has been challenged by profound thrombocytopenia and fatal coagulopathy in non-human primate models. Here we suggest that a left auxiliary technique can be a useful method to achieve extended survival of the xenograft. Fifteen consecutive liver xenotransplants were carried out in a pig-to-cynomolgus model. Right au

본 연구에서는 특수학교의 중고등부 교사들을 대상으로 교사의 하루일과를 참여관찰하고, 교사들의 과정활동과 인간관계 그리고 업무를 심층면담을 통해 살펴보았다. 본 연구의 분석결과는 특수학교 교사의 하루일과는 ‘빈틈없이 반복되는 삶에 의미 부여하기’, 특수학교 교사들의 과정활동은 ‘개별화교육계획(IEP)에 의한 수업하기’와 ‘교육활동을 위한 협의와 조율하기’, 특수학교 교사와 인간관계는 ‘어색함으로 인해 공무에만 만나기’, ‘매개적 역할로 인해 부담 없이 요구하기’, ‘가족처럼 친밀한 유대와 편하게 지내기’, ‘가까이도 멀리도 할 수 없어 일정한 선 유지하기’, ‘자식 대하듯 허물없이 친하게 지내기’, 마지막으로 특수학교 교사들의 업무는 ‘매일 같이 되풀이 되는 업무’, ‘시행착오 속에 인정사정 볼 것 없는 업무’ 등으로 구분될 수 있었다. 끝으로 본 연구결과에 기초하여 특수학교의 교사문화에 대해서 후속연구를 위한 과제를 제시하였다.

Steroids have been a mainstay of immunosuppressive regimens in renal transplantation despite their adverse effects. The introduction of new immunosuppressant has improved the survival rates and prompted trials of steroid withdrawal. We conducted a randomized prospective study to compare steroid withdrawal at 6 months post-transplant between tacrolimus + mycophenolate mofetil (MMF) (FK group) versus cyclosporine A + MMF (CsA group). Steroid was withdrawn at 6 months post-transplant under the cond