서재경 교수

Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease that is characterized by cartilage destruction, osteophyte formation, subchondral bone remodeling, and synovitis. Despite affecting millions of patients, effective and safe disease-modifying osteoarthritis drugs are lacking. Here we reveal an unexpected role for the small molecule 5-aminosalicylic acid (5-ASA), which is used as an anti-inflammatory drug in ulcerative colitis. We show that 5-ASA competes with extrace

Peri-prosthetic patellar fracture following resurfacing as part of total knee replacement (TKR) is an infrequent yet challenging complication. This case-control study was performed to identify clinical, radiological and surgical factors that increase the risk of developing a spontaneous patellar fracture after TKR. Patellar fractures were identified in 74 patients (88 knees) from a series of 7866 consecutive TKRs conducted between 1998 and 2009. After excluding those with a previous history of e

Background The purpose of this study is to report the outcome of navigation-assisted cruciate-retaining total knee arthroplasty (TKA) using one type of cemented, second-generation, floating-platform (FP), mobile-bearing system. Methods We retrospectively reviewed 42 patients (51 knees) who underwent cruciate retaining TKAs using e.motion-FP prostheses under navigational guidance. The preoperative diagnosis was osteoarthritis in all knees except one rheumatoid arthritis. There were 2 men (2 knees

이 연구는 정기적인 생활체육 활동에 참여하는 노인이 지각한 신체적 자기효능감과 건강증진행동 그리고 여가만족, 운동지속의 구조적 관계를 검증하는 데 목적이 있었다. 연구의 목적을 달성하기 위해 전라도 권역에 거주하는 268명의 노인을 대상으로 자료를 수집했다. 수집된 자료는 확인적 요인분석과 신뢰도 검증을 진행하여 문항의 타당도와 신뢰도를 검증했다. 이후 기술통계, 상관관계 분석, 구조방정식모형을 설정하여 분석을 진행했다. 연구모형의 적합도는 수용할 만한 적합도가 확인되었다. 이에 연구 결과를 해석하는 데 문제가 없는 수준으로 판단했다. 변인 간 경로계수 결과를 살펴보면, 생활체육 노인이 지각한 신체적 자기효능감은 건강증진행동에 영향을 미치는 것으로 나타났다. 또한 운동지속에 유의한 영향을 미치는 것으로 확인되었다. 건강증진행동은 여가만족과 운동지속에 유의한 영향을 미치는 것으로 나타났다. 그리고 여가만족은 운동지속에 유의한 영향을 미치는 것으로 확인되었다. 노인의 정기적인 신체활동을

Introduction We sought to determine the 10-year survivorship of single-radius, posterior-stabilized total knee arthroplasty (TKA) in Asian patients. We also aimed to determine whether the long-term clinical and radiographic results differed between patients with and without patellar resurfacing. Materials and Methods This retrospective study included 148 (115 patients) consecutive single-radius, posterior-stabilized TKAs. Ten-year survivorship analysis was performed using the Kaplan-Meier method

The surge of high-performance computing and AI has driven demand for advanced packaging such as chiplet-to-HBM integration, pushing the industry toward fan-out panel-level packaging (FOPLP). To meet the sub-2 µm fine-pitch RDL requirements of next-generation heterogeneous systems, the semi-additive process (SAP) suffers from diffusion-barrier loss, weak Ti adhesion, and Cu undulation. This work presents a semi-etch process (SEP) that combines lithography, anisotropic dry etching, Ti/Cu barrier f

Background Management of the patella with poor bone stock remains a challenge in revision total knee arthroplasty (TKA). The purpose of this study was to evaluate the results of a novel surgical technique in which widely available wires and acrylic bone cement are used in the reconstruction of a deficient patella. Methods Twenty-eight patients (30 knees) underwent revision TKA in which a deficient patella was treated with an onlay-type prosthesis and bone-augmenting procedure, using transcortica