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고재훈 교수

Jae‐Hoon Ko

성균관대학교 의학과 · 의학

연구실 소개

고재훈 교수의 연구실은 감염병 역학과 면역학을 기반으로 한 전염병의 면역 반응 및 진단 기술 개발에 중점을 두고 있습니다. 특히 코로나19 환자에서의 항체 생성 패tern, 변이 바이러스에 대한 T세포 반응, 그리고 신속진단키트의 임상적 유용성에 대한 연구를 진행하고 있습니다. 또한, 최근에는 3D 이미지 재구성 기술과 면역 반응의 상관관계를 탐색하는 기초-임상 융합 연구도 전개하고 있습니다.

SARS-CoV-2면역 반응항체 진단변이 바이러스3D GAN

연구 현황

논문 수
191
총 인용 수
3,595
최근 5년 논문
83
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
83총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
645총합
20222023202420252026

주요 논문

15
1
논문|인용수 168·2016
Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients
Jae‐Hoon Ko, Ga Eun Park, Ji Yeon Lee, Ji‐Yong Lee, Sun Young Cho, Young Eun Ha, Cheol‐In Kang, Ji‐Man Kang, Yae‐Jean Kim, Hee Jae Huh, Chang‐Seok Ki, Byeong‐Ho Jeong
SJR Q1Journal of InfectionOA
Infectious DiseasesMedicine
2
논문|인용수 133·2020
Neutralizing Antibody Production in Asymptomatic and Mild COVID-19 Patients, in Comparison with Pneumonic COVID-19 Patients
Jae‐Hoon Ko, Eun‐Jeong Joo, Su‐Jin Park, Jin Yang Baek, Won Duk Kim, Jaehwan Jee, Chul‐Joong Kim, Chul Hoi Jeong, Yae-Jean Kim, Hye Jin Shon, Eun‐Suk Kang, Young Ki Choi
SJR Q1Journal of Clinical MedicineOA

Objectives: To investigate antibody production in asymptomatic and mild COVID-19 patients. Methods: Sera from asymptomatic to severe COVID-19 patients were collected. Microneutralization (MN), fluorescence immunoassay (FIA), and enzyme-linked immunosorbent assay (ELISA) were performed. Results: A total of 70 laboratory-confirmed COVID-19 patients were evaluated, including 15 asymptomatic/anosmia, 49 mild symptomatic, and 6 pneumonia patients. The production of the neutralizing antibody was obser

Infectious DiseasesMedicine
3
리뷰|인용수 109·2018
Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment of Stenotrophomonas maltophilia infections: a systematic review and meta-analysis
Jae‐Hoon Ko, Cheol‐In Kang, Patricia Cornejo‐Juárez, Kuo‐Ming Yeh, C.-H. Wang, S.Y. Cho, Mustafa Gökhan Gözel, Seon‐Hee Kim, Po‐Ren Hsueh, Noritaka Sekiya, Yasufumi Matsumura, Dong‐Gun Lee
SJR Q1Clinical Microbiology and InfectionOA
EndocrinologyBiochemistry, Genetics and Molecular Biology
4
논문|인용수 106·2014
Clinical Presentation and Risk Factors for Cytomegalovirus Colitis in Immunocompetent Adult Patients
Jae‐Hoon Ko, Kyong Ran Peck, Won Jin Lee, Ji‐Yong Lee, S. Y. Cho, Young Eun Ha, Cheol‐In Kang, Doo Ryeon Chung, Youngsun Kim, Nam Yong Lee, K.-M. Kim, Jae‐Hoon Song
SJR Q1Clinical Infectious DiseasesOA

Steroid use and RBC transfusion within 1 month of the diagnosis of colitis were independent risk factors for development of CMV colitis in immunocompetent hosts.

EpidemiologyMedicine
5
논문|인용수 80·2017
Serologic responses of 42 MERS-coronavirus-infected patients according to the disease severity
Jae‐Hoon Ko, Marcel A. Müller, Hyeri Seok, Ga Eun Park, Ji Yeon Lee, Sun Young Cho, Young Eun Ha, Jin Yang Baek, Kim Ys, Ji‐Man Kang, Yae‐Jean Kim, Ik Joon Jo
SJR Q2Diagnostic Microbiology and Infectious DiseaseOA
Infectious DiseasesMedicine
6
논문|인용수 49·2023
3D GAN Inversion with Pose Optimization
Jae‐Hoon Ko, Kyusun Cho, Daewon Choi, Kwangrok Ryoo, Seungryong Kim
2023 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV)

With the recent advances in NeRF-based 3D aware GANs quality, projecting an image into the latent space of these 3D-aware GANs has a natural advantage over 2D GAN inversion: not only does it allow multi-view consistent editing of the projected image, but it also enables 3D reconstruction and novel view synthesis when given only a single image. However, the explicit viewpoint control acts as a main hindrance in the 3D GAN inversion process, as both camera pose and latent code have to be optimized

Computer Vision and Pattern RecognitionComputer Science
7
논문|인용수 39·2019
Poor prognosis of Candida tropicalis among non-albicans candidemia: a retrospective multicenter cohort study, Korea
Jae‐Hoon Ko, Dong Sik Jung, Ji Yeon Lee, Hyun Ah Kim, Seong Yeol Ryu, Sook‐In Jung, Eun‐Jeong Joo, Shinhye Cheon, Kim Ys, Shin‐Woo Kim, Sun Young Cho, Cheol‐In Kang
SJR Q2Diagnostic Microbiology and Infectious Disease
Infectious DiseasesMedicine
8
논문|인용수 36·2015
Bacteremic meningitis caused by Parvimonas micra in an immunocompetent host
Jae‐Hoon Ko, Jin Yang Baek, Cheol‐In Kang, Woo Joo Lee, Ji‐Yong Lee, Sun Young Cho, Young Eun Ha, Kim Ys, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae‐Hoon Song
SJR Q2Anaerobe
MicrobiologyImmunology and Microbiology
9
논문|인용수 32·2017
Appropriate non-carbapenems are not inferior to carbapenems as initial empirical therapy for bacteremia caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae: a propensity score weighted multicenter cohort study
Jae‐Hoon Ko, Nancy Lee, Eun‐Jeong Joo, Soo‐youn Moon, J.‐K. Choi, D. A. Park, Kyong Ran Peck
SJR Q1European Journal of Clinical Microbiology & Infectious Diseases
Molecular MedicineBiochemistry, Genetics and Molecular Biology
10
논문|인용수 29·2019
Ongoing outbreak of human adenovirus-associated acute respiratory illness in the Republic of Korea military, 2013 to 2018
Jae‐Hoon Ko, Hyeongtaek Woo, Hong Sang Oh, Song Mi Moon, Joon Young Choi, Jeong Uk Lim, Dong‐Hoon Kim, Junsu Byun, Soon‐Hwan Kwon, Daeyoun Kang, Jung Yeon Heo, Kyong Ran Peck
SJR Q2The Korean Journal of Internal MedicineOA

A large HAdV outbreak is currently ongoing in the Korean military, with a trend away from seasonality, and HAdV-55 is likely the predominant strain. Persistent efforts to control the outbreak, HAdV type-specific surveillance, and vaccine development are required.

EpidemiologyMedicine
11
논문|인용수 29·2018
Changing epidemiology of non-albicans candidemia in Korea
Jae‐Hoon Ko, Dong Sik Jung, Ji Yeon Lee, Hyun Ah Kim, Seong Yeol Ryu, Sook‐In Jung, Eun‐Jeong Joo, Shinhye Cheon, Kim Ys, Shin‐Woo Kim, Sun Young Cho, Cheol‐In Kang
SJR Q2Journal of Infection and Chemotherapy
Infectious DiseasesMedicine
12
논문|인용수 25·2019
Early cidofovir administration might be associated with a lower probability of respiratory failure in treating human adenovirus pneumonia: a retrospective cohort study
Jae‐Hoon Ko, Jeong Uk Lim, Joon Young Choi, Hong Sang Oh, Hongseok Yoo, Byung Woo Jhun, Kyungmin Huh, Kyong Ran Peck
SJR Q1Clinical Microbiology and InfectionOA
GeneticsBiochemistry, Genetics and Molecular Biology
13
논문|인용수 25·2017
Suggested new breakpoints of anti-MERS-CoV antibody ELISA titers: performance analysis of serologic tests
Jae‐Hoon Ko, Marcel A. Müller, Hyeri Seok, Geun‐Young Park, Ji‐Yong Lee, S. Y. Cho, Young Eun Ha, Jin Yang Baek, S.-H. Kim, Ji‐Man Kang, Y.-J. Kim, Ik Joon Jo
SJR Q1European Journal of Clinical Microbiology & Infectious DiseasesOA
Infectious DiseasesMedicine
14
논문|인용수 21·2014
Risk factors for cytomegalovirus gastrointestinal diseases in adult patients with cancer
Jae‐Hoon Ko, Kyong Ran Peck, Won Jae Lee, Kyungmin Huh, Jeong Rae Yoo, Kihyun Kım, S. Y. Cho, Young Eun Ha, Cheol‐In Kang, Doo Ryeon Chung, Chul Won Jung, Youngsun Kim
SJR Q1European Journal of Clinical Microbiology & Infectious Diseases
EpidemiologyMedicine
15
논문|인용수 20·2024
Omicron BA.2 breakthrough infection elicits CD8 + T cell responses recognizing the spike of later Omicron subvariants
Sang-Hoon Kim, Jihye Kim, Sungmin Jung, Ji Yun Noh, Jin Nam Kim, Heedo Park, Young Goo Song, Kyong Ran Peck, Su‐Hyung Park, Man‐Seong Park, Jae‐Hoon Ko, Joon Young Song
SJR Q1Science Immunology

Here, we examine peripheral blood memory T cell responses against the SARS-CoV-2 BA.4/BA.5 variant spike among vaccinated individuals with or without Omicron breakthrough infections. We provide evidence supporting a lack of original antigenic sin in CD8 + T cell responses targeting the spike. We show that BNT162b2-induced memory T cells respond to the BA.4/BA.5 spike. Among individuals with BA.1/BA.2 breakthrough infections, IFN-γ–producing CD8 + T cell responses against the BA.4/BA.5 spike incr

Infectious DiseasesMedicine

대표 연구 분야

Infectious DiseasesEpidemiologyMolecular MedicineSurgeryComputer Networks and CommunicationsOncology

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