이재명 교수
Jaemyung Lee
고려대학교 마케팅학과 · 의학
연구실 소개
이재명 교수의 연구실은 생체 내 미량원소 대사와 면역조절 메커니즘을 중심으로 중환자 치료 및 암 치료의 임상적 결과를 향상시키는 데 초점을 맞추고 있습니다. 특히, 중환자에서의 미량원소 농도 변화와 면역세포 분화 비율(Th1/Th2, Th17/Treg) 변화를 분석하여 약물(예: 덱스메데토미딘)의 영향을 평가하는 연구를 진행하고 있습니다. 또한, 생체적합성 소재를 활용한 웨어러블 에너지 저장 장치 개발을 통해 의료용 소재의 혁신도 함께 추구하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15We measured serum concentrations of trace elements and evaluated their clinical significance in relation to treatment outcomes of critically ill patients. A total of 167 participants (105 men and 62 women; average age, 61.4 years; age range, 18-90 years) were enrolled. Arterial blood concentrations of the trace elements zinc, copper, selenium, and manganese were measured every 14 days. At the time of intensive care unit (ICU) admission, serum concentrations of zinc, selenium, copper, and mangane
Flexible yarn- or fiber-based energy storing devices are attractive because of their small dimension, light weight, and suitability for integration into woven or textile application. Some Li-ion based yarn or fiber batteries were developed due to their performance advantages, realizing highly performing and practically safe wearable battery still remains a challenge. Here, high performance and safe yarn-based battery is demonstrated by embedding active materials into inner structure of yarn and
The aims of this study were to evaluate both the efficacy of stent placement for treating inferior vena cava (IVC) stenosis and the patency of hepatic veins (HVs) following IVC stent placement. Fourteen hepatic transplant recipients underwent stent placement to treat IVC stenosis. The median interval between transplantation and stent placement was 32 days. Stents varied from 20-36 mm in diameter and were 60-120 mm long. We retrospectively analyzed the technical and clinical success, changes of h
We determined the influence of bile spillage on recurrence and survival during laparoscopic cholecystectomy (LC) for gallbladder (GB) cancer. Among the 136 patients with GB cancer treated at Ajou University Hospital between 1994 and 2007, 28 underwent LC alone. We compared patients without bile spillage (bile spillage [-] group, n = 16) with patients who had bile spillage (bile spillage [+] group, n = 12). There was no statistical difference in stage between the groups. In the bile spillage (-)
BACKGROUND: The ratio of T helper 1 (Th1) to T helper 2 (Th2) as well as T helper 17 (Th17) to regulatory T cells (Treg) represents the state and direction of immune response. Recent studies demonstrated that dexmedetomidine reduced the secretion of inflammatory cytokines. We performed this study to investigate the effect of different doses of intraoperative dexmedetomidine on the expression of Th1, Th2, T17 and Treg cytokines and their ratios. METHODS: Seventy-five patients undergoing laparosco
These findings suggest that lidocaine and procaine dose-dependently preserve endothelium-dependent vasorelaxation against ROS attack, potentially via hydrogen peroxide scavenging.
Metastasis of hepatocellular carcinoma (HCC) to the ovary is notably rare. We present a case of HCC metastasis to the ovary with a review of the literature, which includes only 7 reported cases. A 43-year-old hepatitis B virus carrier was admitted with a right ovarian cystic mass. She had been diagnosed with HCC 2 years prior, for which she underwent transarterial chemoembolization followed by right posterior sectionectomy. Eight months after the hepatectomy, the first intrahepatic recurrence wa
A solid pseudopapillary tumor (SPT) is a pancreatic neoplasm of low malignant potential. The potentially malignant pathologic features of SPTs were regarded as angioinvasion, perineural invasion, deep invasion of the surrounding acinar tissue, and nuclear pleomorphism. We retrospectively reviewed 31 cases of SPTs (25 female and 6 male patients, with an average age of 35 ± 14 years). The mean follow-up period was 132.0 ± 55.9 months. To evaluate the clinical impact of above pathological parameter
Cyber attacks targeting the Supervisory Control and Data Acquisition (SCADA) systems are becoming more complex and more intelligent. Currently proposed security measures for the SCADA systems come under three categories: physical/logical network separation, communication message security, and security monitoring. However, the recent malwares which were used successfully to disrupt the critical systems show that these security strategies are necessary, but not sufficient to defend these malwares.
BACKGROUND/AIMS: We report a single center experience of 12 cases with neuroendocrine tumor (NET) of the gallbladder. METHODOLOGY: Twelve patients were diagnosed with gallbladder NET between July 1998 and February 2008 and assessed according to the WHO histological classification. Six patients underwent surgical resection and 6 patients underwent nonsurgical treatment. RESULTS: There was one well-differentiated neuroendocrine carcinoma (NEC), 6 poorly differentiated NECs, and 5 mixed exocrine-en
Abstract Yarn‐ or fiber‐structured batteries have been studied steadily due to their huge advantages such as light weight, small size and flexibility. Although some fiber structured batteries were reported, large size and complicated fabrication process still remain to be major challenges in developing practical battery systems. In order to address these problems, we fabricated a micro‐sized and continuous Ag−Zn fiber battery using wet spinning and electrodeposition. This simple and easy process
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