박재석 교수

T(1)-weighted contrast is conventionally obtained using multislice two-dimensional (2D) spin-echo (SE) imaging. Achieving isotropic, high spatial resolution is problematic with conventional methods due to a long acquisition time, imperfect slice profiles, or high-energy deposition. Single-slab 3D SE imaging was recently developed employing long echo trains with variable low flip angles to address these problems. However, long echo trains may yield suboptimal T(1)-weighted contrast, since T(2) we

A parallel imaging technique, GRAPPA (GeneRalized Auto-calibrating Partially Parallel Acquisitions), has been used to improve temporal or spatial resolution. Coil calibration in GRAPPA is performed in central k-space by fitting a target signal using its adjacent signals. Missing signals in outer k-space are reconstructed. However, coil calibration operates with signals that exhibit large amplitude variation while reconstruction is performed using signals with small amplitude variation. Different

Contrast-enhanced three-dimensional T(1)-weighted imaging based on magnetization-prepared rapid-gradient recalled echo is widely used for detecting small brain metastases. However, since contrast materials remain in both blood and the tumor parenchyma and thus increase the signal intensity of both regions, it is often challenging to distinguish brain tumors from blood. In this work, we develop a T(1)-weighted, black-blood version of single-slab three-dimensional turbo/fast spin echo whole-brain

Compared with conventional MP-RAGE, the proposed CE BB-ssTSE imaging, which enhances tumors while selectively suppressing blood vessels, leads to significantly better detection of small metastatic brain tumors <5 mm.

Coronary artery data acquisition with steady-state free precession (SSFP) is typically performed in a single frame in mid-diastole with a spectrally selective pulse to suppress epicardial fat signal. Data are acquired while the signal approaches steady state, which may lead to artifacts from the SSFP transient response. To avoid sensitivity to cardiac motion, an accurate trigger delay and data acquisition window must be determined. Cine data acquisition is an alternative approach for resolving t

Spatial resolution in 3D breath-hold coronary MR angiography (MRA) is limited by imaging time. The purpose of this work was to investigate the feasibility of improving the spatial resolution of coronary MRA using generalized autocalibrating partially parallel acquisition (GRAPPA) and fast imaging with steady state precession (True-FISP) data acquisition. Coronary data were acquired in 10 healthy volunteers. In five volunteers, the data were fully acquired in k-space and decimated for GRAPPA with

Recently, three-dimensional integrated circuit (3-D IC) design has attracted much attention, and the reliability of these systems has become increasingly important. In this paper, a new repairable and reliable through-silicon via (TSV) set structure is proposed. This proposed TSV set structure can be applied to the previous TSV repair structures which require TSV redundancies, and detects a defect or error reutilizing residual TSV redundancies for high reliability of 3-D ICs. Both online test an

Single-slab 3D turbo/fast spin echo (SE) imaging with very long echo trains was recently introduced with slab selection using a highly selective excitation pulse and short, nonselective refocusing pulses with variable flip angles for high imaging efficiency. This technique, however, is vulnerable to image degradation in the presence of spatially varying B(1) amplitudes. In this work we develop a B(1) inhomogeneity-reduced version of single-slab 3D turbo/fast SE imaging based on the hypothesis th

PURPOSE: To make clinically feasible whole-brain chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) by enhancing imaging efficiency. METHODS: A novel, whole-brain three-dimensional (3D) steady-state CEST MRI method was introduced by utilizing a time-efficient, fat-suppressed excitation followed by rapid, segmented 3D echo-planar-imaging with incoherent undersampling in k-ω space. Missing signals and CEST-specific spectral images were then jointly estimated directly fro

Parallel magnetic resonance imaging in k-space such as generalized auto-calibrating partially parallel acquisition exploits spatial correlation among neighboring signals over multiple coils in calibration to estimate missing signals in reconstruction. It is often challenging to achieve accurate calibration information due to data corruption with noises and spatially varying correlation. The purpose of this work is to address these problems simultaneously by developing a new, adaptive iterative g

This paper proposes a dual channel timing formatter system for high speed memory test equipment. The proposed architecture supports 256 kinds of waveform with 20ps timing resolution. Moreover, timing problem is reduced because a timing generator is embedded.

To reduce the secondary damage caused by leakage accidents in plant piping systems, a constant surveillance system is necessary. To ensure leaks are promptly addressed, the surveillance system should be able to detect not only the leak itself, but also the location of the leak. Recently, research to develop new methods has been conducted using cameras to detect leakage and to estimate the location of leakage. However, existing methods solely estimate whether a leak exists or not, or only provide

PURPOSE: To develop a novel, simultaneous multislice reconstruction method that exploits Hankel subspace learning (SMS-HSL) for aliasing separation in the slice direction. METHODS: An SMS signal model with the Hankel-structured matrix was proposed. To efficiently suppress interslice leakage artifacts from a signal subspace perspective, a null space was learned from the reference data combined over all slices other than a slice of interest using singular value decomposition. Given the fact that t

Coronary artery imaging data are conventionally acquired in a single imaging frame during mid-diastole. The data acquisition window must be sufficiently short to avoid cardiac motion artifacts. A short data acquisition window results in decreased imaging efficiency and limited spatial resolution. Parallel imaging may lessen these limitations, but requires highly accurate coil sensitivity. The purpose of this work was to increase the imaging efficiency and spatial resolution in coronary artery im