최장환 교수
Jang-hwan Choi
이화여자대학교 의학과 · 의학
연구실 소개
최장환 교수의 연구실은 의료 영상 진단의 정밀도를 향상시키기 위해 첨단 영상 재구성 기술과 인공지능 기반 분석 방법을 융합한 연구를 수행하고 있습니다. 특히, 체중을 싣고 있는 상태에서의 하체 영상 촬영 시 발생하는 비의도적 운동 보정, 저선량 CT 촬영의 품질 평가, 그리고 패널티 캐나서 등 다양한 영상 데이터를 기반으로 한 암 조기 진단 기술 개발에 주력하고 있습니다. 특히 자기지도 학습 및 딥러닝 기반 모델을 활용해 레이블이 부족한 의료 영상 데이터에서도 높은 정확도로 질병을 탐지하는 기술을 개발하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15PURPOSE: A C-arm CT system has been shown to be capable of scanning a single cadaver leg under loaded conditions by virtue of its highly flexible acquisition trajectories. In Part I of this study, using the 4D XCAT-based numerical simulation, the authors predicted that the involuntary motion in the lower body of subjects in weight-bearing positions would seriously degrade image quality and the authors suggested three motion compensation methods by which the reconstructions could be corrected to
PURPOSE: Human subjects in standing positions are apt to show much more involuntary motion than in supine positions. The authors aimed to simulate a complicated realistic lower body movement using the four-dimensional (4D) digital extended cardiac-torso (XCAT) phantom. The authors also investigated fiducial marker-based motion compensation methods in two-dimensional (2D) and three-dimensional (3D) space. The level of involuntary movement-induced artifacts and image quality improvement were inves
The aim of this study was to develop a novel deep learning (DL) model without requiring large-annotated training datasets for detecting pancreatic cancer (PC) using computed tomography (CT) images. This retrospective diagnostic study was conducted using CT images collected from 2004 and 2019 from 4287 patients diagnosed with PC. We proposed a self-supervised learning algorithm (pseudo-lesion segmentation (PS)) for PC classification, which was trained with and without PS and validated on randomly
Due to high recurrence rates in patients with non-small cell lung cancer (NSCLC), medical professionals need extremely accurate diagnostic methods to prevent bleak prognoses. However, even the most commonly used diagnostic method, the TNM staging system, which describes the tumor-size, nodal-involvement, and presence of metastasis, is often inaccurate in predicting NSCLC recurrence. These limitations make it difficult for clinicians to tailor treatments to individual patients. Here, we propose a
Abstract Accurate image quality assessment (IQA) is crucial to optimize computed tomography (CT) image protocols while keeping the radiation dose as low as reasonably achievable. In the medical domain, IQA is based on how well an image provides a useful and efficient presentation necessary for physicians to make a diagnosis. Moreover, IQA results should be consistent with radiologists’ opinions on image quality, which is accepted as the gold standard for medical IQA. As such, the goals of medica
Deep convolutional networks have been developed to detect prohibited items for automated inspection of X-ray screening systems in the transport security system. To our knowledge, the existing frameworks were developed to recognize threats using only baggage security X-ray scans. Therefore, the detection accuracy in other domains of security X-ray scans, such as cargo X-ray scans, cannot be ensured. We propose an object detection method for efficiently detecting contraband items in both cargo and
In the medical field, various clinical information has been accumulated to help clinicians provide personalized medicine and make better diagnoses. As chronic diseases share similar characteristics, it is possible to predict multiple chronic diseases using the accumulated data of each patient. Thus, we propose an intra-person multi-task learning framework that jointly predicts the status of correlated chronic diseases and improves the model performance. Because chronic diseases occur over a long
Deep neural networks have shown great improvements in low-dose computed tomography (CT) denoising. Early algorithms were primarily optimized to obtain an accurate image with low distortion between the denoised image and reference full-dose image at the cost of yielding an overly smoothed unrealistic CT image. Recent research has sought to preserve the fine details of denoised images with high perceptual quality, which has been accompanied by a decrease in objective quality due to a trade-off bet
Patellofemoral pain (PFP) is commonly caused by abnormal pressure on the knee due to excessive load while standing, squatting, or going up or down stairs. To better understand the pathophysiology of PFP, we conducted a noninvasive patellar tracking study using a C-arm computed tomography (CT) scanner to assess the non-weight-bearing condition at 0° knee flexion (NWB0°) in supine, weight-bearing at 0° (WB0°) when upright, and at 30° (WB30°) in a squat. Three-dimensional (3D) CT images were obtain
BACKGROUND: Although low-dose computed tomography (CT) imaging has been more widely adopted in clinical practice to reduce radiation exposure to patients, the reconstructed CT images tend to have more noise, which impedes accurate diagnosis. Recently, deep neural networks using convolutional neural networks to reduce noise in the reconstructed low-dose CT images have shown considerable improvement. However, they need a large number of paired normal- and low-dose CT images to fully train the netw
Although diabetes mellitus is a complex and pervasive disease, most studies to date have focused on individual features, rather than considering the complexities of multivariate, multi-instance, and time-series data. In this study, we developed a novel diabetes prediction model that incorporates these complex data types. We applied advanced techniques of data imputation (bidirectional recurrent imputation for time series; BRITS) and feature selection (the least absolute shrinkage and selection o
Several state-of-the-art object detectors have demonstrated outstanding performances by optimizing feature representation through modification of the backbone architecture and exploitation of a feature pyramid. To determine the effectiveness of this approach, we explore the modification of object detectors' backbone and feature pyramid by utilizing Neural Architecture Search (NAS) and Capsule Network. We introduce two modules, namely, NAS-gate convolutional module and Capsule Attention module. T
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