박제연 교수

The Nuclear power plant (NPP) industries in Korea have been making efforts to reduce the human errors which largely contributed to 120 nuclear reactor trips from the year of 2001 to 2006. This study aims to develop a Crew Resource Management (CRM) training program that helps to improve plant performance by reducing the number of the reactor trips caused by the operators' errors. The CRM program was developed with focusing on nontechnical skills, such as leadership, situation awareness, teamwork,

Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L). CD11c + MHCII + or CD11c + MHCII hi cells are routinely isolated from those BM cultures and generally used as in vitro -generated DCs for a variety of experiments and therapies. Here, we examined CD11c + cells in the BM culture with GM-CSF or FLT3L by staining with a monoclonal antibody 2

Abstract Psoriasis is largely mediated by interleukin ( IL )‐23/T helper (Th) 17 axis, and IL ‐21 is a pleiotropic cytokine expressed by Th17 cells. Despite previously reported possible pathogenic roles of IL ‐21 in human psoriasis, we found that IL ‐21 receptor ( IL ‐21R) signalling was not crucial for imiquimod‐induced psoriatic inflammation, using IL ‐21R −/− mice. The severity of imiquimod‐induced psoriatic manifestation and pro‐inflammatory Th17 cytokine levels, IL ‐17A‐producing γδ T cells

The skin is the outermost barrier organ in the body, which contains several types of dendritic cells (DCs), a group of professional antigen-presenting cells. When the skin encounters invading pathogens, different cutaneous DCs initiate a distinct T cell immune response to protect the body. Among the invading pathogens, fungal infection specifically drives a protective interleukin-17-producing Th17 immune response. A protocol was developed to efficiently differentiate Th17 cells by intradermal Ca