박지은 교수
Jee Eun Park
서울대학교 정신과 · 의학
연구실 소개
박지은 교수의 연구실은 의료 영상 기반 정량적 분석인 레이디오믹스를 핵심으로, 뇌신경종양의 조기 재발 여부를 정밀하게 구분하는 영상기반 예측 모델 개발에 주력하고 있습니다. 기후 요인과 감염병 유병률 간의 상관관계 분석, 심리적 정서 상태 평가를 위한 심박수 변동성(HRV) 분석 등 다양한 의료 및 사회과학적 문제에 응용 가능한 다학제적 접근을 펼치고 있습니다. 특히, 영상 데이터의 재현성과 과적합 방지를 위한 통계적 모델링 기법 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Radiomics, which involves the use of high-dimensional quantitative imaging features for predictive purposes, is a powerful tool for developing and testing medical hypotheses. Radiologic and statistical challenges in radiomics include those related to the reproducibility of imaging data, control of overfitting due to high dimensionality, and the generalizability of modeling. The aims of this review article are to clarify the distinctions between radiomics features and other omics and imaging data
The transmissibility and severity of MERS differed by outbreak region and patient characteristics. Further studies assessing the risk of MERS should consider these factors.
BACKGROUND: The effect of temperature and humidity on the incidence of influenza may differ by climate region. In addition, the effect of diurnal temperature range on influenza incidence is unclear, according to previous study findings. OBJECTIVES: The aim of this study was to analyze the effects of temperature, humidity, and diurnal temperature range on the incidence of influenza in Seoul, Republic of Korea, which is located in a temperate region. METHODS: We used Korean National Health insuran
BACKGROUND: Pseudoprogression is a diagnostic challenge in early posttreatment glioblastoma. We therefore developed and validated a radiomics model using multiparametric MRI to differentiate pseudoprogression from early tumor progression in patients with glioblastoma. METHODS: The model was developed from the enlarging contrast-enhancing portions of 61 glioblastomas within 3 months after standard treatment with 6472 radiomic features being obtained from contrast-enhanced T1-weighted imaging, flu
Because human emotion varies greatly among individuals and is a qualitative factor, measuring it with any degree of accuracy is very difficult. Heart rate variability (HRV), which is used in evaluations of the autonomic nervous system (ANS), is used to evaluate human emotions. This study examines the validity of HRV as a tool to evaluate emotions using the International Affective Picture System (IAPS). For experimentation, five photos were selected for each of the categories of "happy," "unhappy
Purpose Innovative consumers are an important market segment. This paper seeks to investigate whether consumers' innate innovativeness is associated with their shopping styles. Specifically, it aims to explore the relationship between two types of innovativeness – sensory and cognitive – and consumer shopping styles. Design/methodology/approach The paper integrates the consumer innovativeness and consumer shopping styles literature. It is built on the premise that if consumer innovativeness is r
Background: Radiomics is a rapidly growing field in neuro-oncology, but studies have been limited to conventional MRI, and external validation is critically lacking. We evaluated technical feasibility, diagnostic performance, and generalizability of a diffusion radiomics model for identifying atypical primary central nervous system lymphoma (PCNSL) mimicking glioblastoma. Methods: A total of 1618 radiomics features were extracted from diffusion and conventional MRI from 112 patients (training se
We aimed to establish a high-performing and robust classification strategy, using magnetic resonance imaging (MRI), along with combinations of feature extraction and selection in human and machine learning using radiomics or deep features by employing a small dataset. Using diffusion and contrast-enhanced T1-weighted MR images obtained from patients with glioblastomas and primary central nervous system lymphomas, classification task was assigned to a combination of radiomic features and (1) supe
BACKGROUND: To evaluate radiomics analysis in neuro-oncologic studies according to a radiomics quality score (RQS) system to find room for improvement in clinical use. METHODS: Pubmed and Embase were searched up the terms radiomics or radiogenomics and gliomas or glioblastomas until February 2019. From 189 articles, 51 original research articles reporting the diagnostic, prognostic, or predictive utility were selected. The quality of the methodology was evaluated according to the RQS. The adhere
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