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채지원 교수

Jee Won Chai

서울대학교 영상의학과 · 의학

연구실 소개

채지원 교수의 연구실은 주로 관절 질환, 특히 퇴행성 관절염과 어깨 힘줄 손상에 대한 줄기세포 기반 치료법 개발에 초점을 맞추고 있습니다. 자가 지방세포 유래 간엽줄기세포(AD-MSCs)를 관절 내 주입하는 방법을 통해 관절 연골 재생과 증상 개선을 기대하고 있으며, 임상적 안전성과 중기적 효과를 다각도로 평가하고 있습니다. 또한 뇌척수염 및 경추관 협착에 대한 MRI 영상 평가 체계 개발을 통해 정밀한 진단 기반도 함께 확립하고 있습니다.

관절염 치료줄기세포 주입AD-MSC중기 임상 평가MRI 진단 체계

연구 현황

논문 수
73
총 인용 수
2,431
최근 5년 논문
24
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
24총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
62총합
20222023202420252026

주요 논문

15
1
논문|인용수 912·2014
Intra‐Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof‐of‐Concept Clinical Trial
Chris Hyunchul Jo, Young Gil Lee, Won Hyoung Shin, Hyang Kim, Jee Won Chai, Eui Cheol Jeong, Ji Eun Kim, Hackjoon Shim, Ji Sun Shin, Il Seob Shin, Jeong Chan, Sohee Oh
SJR Q1Stem CellsOA

Mesenchymal stem cells (MSCs) are known to have a potential for articular cartilage regeneration. However, most studies focused on focal cartilage defect through surgical implantation. For the treatment of generalized cartilage loss in osteoarthritis, an alternative delivery strategy would be more appropriate. The purpose of this study was to assess the safety and efficacy of intra-articular injection of autologous adipose tissue derived MSCs (AD-MSCs) for knee osteoarthritis. We enrolled 18 pat

RheumatologyMedicine
2
논문|인용수 278·2010
Radiologic Diagnosis of Osteoid Osteoma: From Simple to Challenging Findings
Jee Won Chai, Sung Hwan Hong, Ja‐Young Choi, Young Hwan Koh, Joon Woo Lee, Jung‐Ah Choi, Heung Sik Kang
SJR Q1Radiographics

Osteoid osteoma is characterized by an intracortical nidus with a variable amount of calcification, as well as cortical thickening, sclerosis, and bone marrow edema. When these findings are present, a diagnosis of osteoid osteoma is easily made. However, osteoid osteoma may display imaging findings that can be misleading, and it can be difficult to differentiate osteoid osteoma from other conditions such as infection, inflammatory and noninflammatory arthritis, and other tumors. In addition, str

RheumatologyMedicine
3
논문|인용수 245·2017
Intra-articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A 2-Year Follow-up Study
Chris Hyunchul Jo, Jee Won Chai, Eui Cheol Jeong, Sohee Oh, Ji Sun Shin, Hackjoon Shim, Kang Sup Yoon
SJR Q1The American Journal of Sports MedicineOA

BACKGROUND: The intra-articular injection of mesenchymal stem cells (MSCs) into the knee has shown a potential for the treatment of generalized cartilage loss in osteoarthritis (OA). However, there have been few midterm reports with clinical and structural outcomes. PURPOSE: To assess the midterm safety and efficacy of an intra-articular injection of autologous adipose tissue-derived (AD) MSCs for knee OA at 2-year follow-up. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: AD MSCs int

RheumatologyMedicine
4
논문|인용수 230·2011
New MRI Grading System for the Cervical Canal Stenosis
Yusuhn Kang, Joon Woo Lee, Young Hwan Koh, Saebeom Hur, Su Jin Kim, Jee Won Chai, Heung Sik Kang
SJR Q1American Journal of Roentgenology

OBJECTIVE: The purpose of this study was to propose a new MRI grading system for cervical canal stenosis and to evaluate the reproducibility of the system. MATERIALS AND METHODS: Cervical canal stenosis was classified according to the T2-weighted sagittal images into the following grades: grade 0, absence of canal stenosis; grade 1, subarachnoid space obliteration exceeding 50%; grade 2, spinal cord deformity; and grade 3, spinal cord signal change. The MRI scans of 82 patients (37 men and 45 wo

SurgeryMedicine
5
논문|인용수 127·2018
Intratendinous Injection of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Rotator Cuff Disease: A First-In-Human Trial
Chris Hyunchul Jo, Jee Won Chai, Eui Cheol Jeong, Sohee Oh, Paul S. Kim, Jeong Yong Yoon, Kang Sup Yoon
SJR Q1Stem CellsOA

Abstract Despite relatively good results of current symptomatic treatments for rotator cuff disease, there has been an unmet need for fundamental treatments to halt or reverse the progress of disease. The purpose of this study was to assess the safety and efficacy of intratendinous injection of autologous adipose tissue-derived mesenchymal stem cells (AD MSCs) in patients with rotator cuff disease. The first part of the study consists of three dose-escalation cohorts; the low- (1.0 × 107 cells),

SurgeryMedicine
6
논문|인용수 87·2015
A New MRI Grading System for Cervical Foraminal Stenosis Based on Axial T2-Weighted Images
Sujin Kim, Joon Woo Lee, Jee Won Chai, Hye Jin Yoo, Yusuhn Kang, Jiwoon Seo, Joong Mo Ahn, Heung Sik Kang
SJR Q1Korean Journal of RadiologyOA

The new MRI grading system shows sufficient interobserver and intraobserver agreement to reliably assess cervical NFS.

SurgeryMedicine
7
논문|인용수 76·2008
CT Angiography for Living Kidney Donors: Accuracy, Cause of Misinterpretation and Prevalence of Variation
Jee Won Chai, Whal Lee, Yong Yin, Hwan Jun Jae, Jin Wook Chung, Hyeon Hoe Kim, Jae Hyung Park
SJR Q1Korean Journal of RadiologyOA

MDCT provides a reliable method to evaluate the vascular anatomy and variations of living kidney donors.

Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 55·2019
Intratendinous Injection of Mesenchymal Stem Cells for the Treatment of Rotator Cuff Disease: A 2‐Year Follow‐Up Study
Chris Hyunchul Jo, Jee Won Chai, Eui Cheol Jeong, Sohee Oh, Kang Sup Yoon
SJR Q1Arthroscopy The Journal of Arthroscopic and Related Surgery

PURPOSE: To assess the mid-term safety and efficacy of an intratendinous injection of autologous adipose tissue-derived mesenchymal stem cells (AD MSCs) for rotator cuff disease at 2-year follow-up. METHODS: ) groups. For the second part, we planned to include 9 patients receiving the high dose for the evaluation of exploratory efficacy. Clinical outcomes were assessed according to pain, range of motion, muscle strength, functional scores, overall satisfaction and function, and presence of failu

SurgeryMedicine
9
논문|인용수 46·2013
Fatty degeneration of the rotator cuff muscles on pre- and postoperative CT arthrography (CTA): is the Goutallier grading system reliable?
Eugene Lee, Jung‐Ah Choi, Joo Han Oh, Soyeon Ahn, Sung Hwan Hong, Jee Won Chai, Heung Sik Kang
SJR Q2Skeletal Radiology
SurgeryMedicine
10
논문|인용수 24·2019
Ultrasound Microflow Imaging Technology for Diagnosis of Adhesive Capsulitis of the Shoulder
Dong Hyun Kim, Yoon‐Hee Choi, Sohee Oh, Hyo Jin Kim, Jee Won Chai
SJR Q2Journal of Ultrasound in Medicine

OBJECTIVES: To assess the diagnostic accuracy of Superb Microvascular Imaging (SMI; Canon Medical Systems, Otawara, Japan) at the subcoracoid triangle for adhesive capsulitis of the shoulder, to compare the diagnostic value of SMI with that of conventional ultrasound (US) and power Doppler ultrasound (PDUS) findings, and to investigate the correlation between vascular flow on SMI with clinical features. METHODS: Our study included 39 patients with a diagnosis of adhesive capsulitis and 35 health

SurgeryMedicine
11
논문|인용수 22·2008
CT Angiography for Living Kidney Donors: Accuracy, Cause of Misinterpretation and Prevalence of Variation
채지원, 이활, Yong Hu Yin, 제환준, 정진욱, Hyeon Hoe Kim, 박재형

Objective: To determine the accuracy of the use of multi-detector row CT (MDCT) to predict vascular anatomy in living kidney donors and to reveal the prevalence of vascular variations in a Korean population. Materials and Methods: A total of 153 living kidney donors that had undergone preoperative CT and nephrectomy, either with open or laparoscopic surgery, were selected retrospectively. The initial CT results were compared with the surgical findings and repeated review sessions of CT scans wer

12
논문|인용수 18·2014
Visualization of joint and bone using dual-energy CT arthrography with contrast subtraction: in vitro feasibility study using porcine joints
Jee Won Chai, Jung-Ah Choi, Ja Young Choi, Sujin Kim, Sung Hwan Hong, Heung Sik Kang, Sung Hwan Hong, Heung Sik Kang
SJR Q2Skeletal Radiology
Biomedical EngineeringEngineering
13
논문|인용수 15·2016
Quantitative Analysis of Disc Degeneration Using Axial T2 Mapping in a Percutaneous Annular Puncture Model in Rabbits
Jee Won Chai, Heung Sik Kang, Joon Woo Lee, Su Jin Kim, Sung Hwan Hong
SJR Q1Korean Journal of RadiologyOA

T2 relaxation time measured with axial T2 mapping in degenerated discs is a potential method to assess disc degeneration.

Pathology and Forensic MedicineMedicine
14
논문|인용수 12·2014
Ultrasonographic diagnosis of snapping annular ligament in the elbow
Jee Won Chai, Su Jin Kim, Hyun Kyong Lim, Kee Jeong Bae
SJR Q1ULTRASONOGRAPHYOA

Elbow snapping by annular ligament is rare and may be difficult to diagnose, when this Epub ahead of print condition is not familiar. We report a case of elbow snapping by annular ligament diagnosed by ultrasonography, which was confirmed by arthroscopic observation. The ultrasonographic findings were thickening of the annular ligament and snapping in and out of the radiocapitellar joint during elbow flexion and extension on dynamic ultrasonography.

RehabilitationMedicine
15
논문|인용수 6·2016
Radial head button holing: a cause of irreducible anterior radial head dislocation
Su-Mi Shin, Jee Won Chai, Ja Yeon You, Jina Park, Kee Jeong Bae
SJR Q2Skeletal Radiology
RehabilitationMedicine

대표 연구 분야

SurgeryRheumatologyOrthopedics and Sports MedicineRadiology, Nuclear Medicine and ImagingBiomedical EngineeringPathology and Forensic Medicine

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