지유진 교수

BACKGROUND: Oroantral communicating defects, characterized by a connection between the maxillary sinus and the oral cavity, are often induced by tooth extraction, removal of cysts and benign tumors, and resection of malignant tumors. The surgical defect may develop into an oroantral fistula, with resultant patient discomfort and chronic maxillary sinusitis. Small defects may close spontaneously; however, large oroantral defects generally require reconstruction. These large defects can be reconst

Ameloblastoma treatment varies based on the clinical, histopathologic, and radiographic characteristics. Aggressive surgical treatments, such as marginal or segmental resection, have traditionally been implemented, but some conservative surgical methods are also being introduced, including decompression, enucleation, or curettage. The aim of the present study was to evaluate the possibility of applying these conservative surgical treatments to ameloblastoma and to analyze the prognosis of the pr

BACKGROUND: Fibrous dysplasia (FD) is a benign bone lesion characterized by the progressive replacement of normal bone with fibro-osseous connective tissue. The maxilla is the most commonly affected area of facial bone, resulting in facial asymmetry and functional disorders. Surgery is an effective management option and involves removing the diseased bone via an intraoral approach: conservative bone shaving or radical excision and reconstruction. CASE PRESENTATION: This case report describes a m

An oroantral fistula (OAF) or oroantral communication (OAC) is an opening between the oral cavity and the maxillary sinus. If left untreated, these openings may cause chronic maxillary sinusitis. Although small defects (diameter <5 mm) may close spontaneously, larger communications require surgical intervention. Various studies have been conducted on OAC closure using a platelet-rich fibrin (PRF) membrane; most of these prior studies have involved simple direct application of PRF clots. This stu

In MM3 removals, patients with higher BMI showed elevated hs-CRP and higher VAS scores before surgery. Patients with higher anxiety among those undergoing extractions of fully impacted MM3s showed higher preoperative VAS scores. The two main predictors of postoperative complications were BMI and MM3 eruption status.

To evaluate the clinical applicability of using PRF mixed with the synthetic bone materials compared to using PRP and no surgical additives. Four bicortical skull defects were prepared in 4 New Zealand white rabbits. In each, 1 defect was used as control and 3 defects were filled with HA/β-TCP, PRP mixed with HA/β-TCP, and PRF mixed with HA/β-TCP separately. After 8weeks, the rabbits were sacrificed and new bone formation was assessed by soft x-ray, conebeam CT and the histomorphometric analysis

BACKGROUND: Chondroblastomas, which account for approximately 1% of all bone tumors, typically occur in long bones, such as the femur, humerus, and tibia. However, in extremely rare cases, they may also occur in the craniofacial region where the tumor is often found in the squamous portion of the temporomandibular joint (TMJ) and in the temporal bone. CASE PRESENTATION: This case report describes a large chondroblastoma (diameter, approximately 37 mm) that occurred in the TMJ. The tumor was suff

Objectives : Practice-Based Research Networks (PBRNs), collaborations of practitioners and academic researchers, have provided platforms for conducting research to address clinical questions generated from daily routine care. This review aimed to critically analyse articles from PBRNs that are related to complementary and integrative medicine (CIM) and to suggest future directions for a PBRN which is appropriate for Korean Medicine (KM). Methods : PubMed, PBRN registries in Agency for Healthcare

To evaluate the effect of platelet rich plasma(PRP) and platelet rich fibrin(PRF) on bone defects with autogenous bone graft and control(no treatment) in the same rabbit calvaria. Four rabbits were included in prospective study. In each rabbit, four equal 8 mm diameter cranial bone defects were made with trephine drill and it was immediately grafted with PRP, PRF, autogenous bone and one defect was remained with no treatment(control). The defects were evaluated by cone beam CT at 2, 4, 6 and 8 w

골형성을 촉진하는 물질로는 골유도단백(BMP), 혈소판 유래성장인자(PDGF), 형질전환성장인자(TGF-β) 등의 다양한 골형성 기질 등이 있다. 이러한 성장인자는 치유과정 시 조직의 재생에 필수적인 신생혈관의 형성, 세포의 화학 주성 및 분열촉진, 간세포 증식, 기질합성 등을 조절하는 인자로 조직재생에 기여한다. 최근 조직공학 연구가 발전하면서 이러한 국소적 역할을 하는 성장요소들에 대하여 활발히 연구되고 있다. 이러한 노력중 하나가 혈액내 혈소판에 존재하는 여러 성장인자를 임상적으로 이용하고자 혈소판을 농축하여 적용하는 혈소판풍부혈장(PRP)과 혈소판풍부 피브린(PRF) 이다 . PRP와 PRF는 방법의 용이성과 효능면에서 많은 장점을 가지고 있기에 이에 대한 관심과 연구가 지속되고 있다. 하지만 아직 임상적 적용에 대하여 학문적 고찰과 개선이 필요하므로 이에 대한 문헌고찰과 최근의 연구를 살펴 보고자 한다.

The FN-conjugated, microgrooved Ti substrate can provide an effective surface to promote osteoblast differentiation and osteoblast marker gene expression in MSCs.

BACKGROUND: The pedicled buccal fat pad has been used for a long time to reconstruct oral defects due to its ease of flap formation and few complications. Many cases related to reconstruction of defects in the maxilla, such as closing the oroantral fistula, have been reported, but cases related to the reconstruction of defects in the mandible are limited. Under adequate anterior traction, pedicled buccal fat pad can be a reliable and effective method for reconstruction of surgical defects in the