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안지윤 교수

Jee Yun Ahn

서울대학교 안과 · 의학

연구실 소개

안지윤 교수의 연구실은 망막 구조와 기능의 변화를 통해 신경퇴행성 질환, 특히 파킨슨병의 조기 진단과 병태생리적 기전을 규명하는 데 초점을 맞추고 있습니다. 특히 망막 간상세포 복합체 두께 측정, 광학간섭단층촬영(OCT), 시각 기능 검사 및 뇌 도파민 수용체 영상 등을 융합한 다학제적 접근을 통해 신경퇴행성 변화의 생체지표를 탐색하고 있습니다. 또한 망막 변화와 관련된 약물 유발 안과 합병증, 예를 들어 비타민 K 유사 물질로 인한 복합성 각막병변 등에도 관심을 기울이고 있습니다.

파킨슨병망막 두께 측정신경퇴행성 질환OCT약물 유발 안과 합병증

연구 현황

논문 수
146
총 인용 수
5,846
최근 5년 논문
29
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
29총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
350총합
20222023202420252026

주요 논문

15
1
논문|인용수 116·2018
Retinal thinning associates with nigral dopaminergic loss in de novo Parkinson disease
Jeeyun Ahn, Jee‐Young Lee, Tae Wan Kim, Eun Jin Yoon, Sohee Oh, Yu Kyeong Kim, Jong‐Min Kim, Se Joon Woo, Ki Woong Kim, Beomseok Jeon
SJR Q1Neurology

Retinal thinning is present in the early stages of PD, correlates with disease severity, and may be linked to nigral dopaminergic degeneration. Retinal imaging may be useful for detection of pathologic changes occurring in early PD.

NeurologyMedicine
2
논문|인용수 107·2011
The Effect of Adjunctive Intravitreal Bevacizumab for Preventing Postvitrectomy Hemorrhage in Proliferative Diabetic Retinopathy
Jeeyun Ahn, Se Joon Woo, Hum Chung, Kyu Hyung Park
SJR Q1Ophthalmology
OphthalmologyMedicine
3
논문|인용수 86·2013
Pharmacokinetics of Intravitreally Injected Bevacizumab in Vitrectomized Eyes
Jeeyun Ahn, Hyuncheol Kim, Se Joon Woo, Ji Hyun Park, Sun Young Park, Daniel Duck-Jin Hwang, Kyu Hyung Park
SJR Q2Journal of Ocular Pharmacology and Therapeutics

Overall IVB PKs in rabbit eyes after vitrectomy without lensectomy are not substantially different from nonvitrectomized control eyes.

OphthalmologyMedicine
4
논문|인용수 52·2019
Retina Thickness as a Marker of Neurodegeneration in Prodromal Lewy Body Disease
Jee‐Young Lee, Jeeyun Ahn, Sohee Oh, Joo Young Shin, Yu Kyeong Kim, Hyunwoo Nam, Beomseok Jeon
SJR Q1Movement Disorders

Abstract Objectives We investigated retinal change and its relationship with neurodegeneration markers in a prodromal Parkinson cohort. Methods A total of 30 patients with idiopathic rapid eye movement sleep behavior disorder were recruited. Participants underwent olfactory testing, macular optical coherence tomography, microperimetry, contrast sensitivity test, and brain N ‐(3‐[ 18 F]fluoropropyl)‐2‐carbomethoxy‐3‐(4‐iodophenyl) nortropane positron emission tomography. We measured the ganglion

NeurologyMedicine
5
논문|인용수 45·2008
Frontalis sling operation using silicone rod for the correction of ptosis in chronic progressive external ophthalmoplegia
Jeeyun Ahn, N J Kim, Ho-Kyoung Choung, Sung Wook Hwang, Mi-Hae Sung, Matthew J. Lee, Sang In Khwarg
SJR Q1British Journal of Ophthalmology

The frontalis sling operation using silicone rod can safely and effectively correct ptosis in chronic progressive external ophthalmoplegia patients without serious corneal complications.

Pathology and Forensic MedicineMedicine
6
논문|인용수 42·2012
LONG-TERM TEMPORAL CHANGES OF PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS BEFORE AND AFTER PANRETINAL PHOTOCOAGULATION IN SEVERE DIABETIC RETINOPATHY
Jongshin Kim, Se Joon Woo, Jeeyun Ahn, Ki Ho Park, Hum Chung, Kyu Hyung Park
SJR Q1Retina

This study shows that average RNFL thickness after PRP undergoes early thickening and subsequent progressive thinning throughout the 2 years post-PRP. This temporal change varies according to the peripapillary RNFL quadrant. Our results also indicate that temporal RNFL and foveal thickness have a similar pattern of long-term change after PRP.

OphthalmologyMedicine
7
논문|인용수 38·2011
Vortex Keratopathy in a Patient Receiving Vandetanib for Non-Small Cell Lung Cancer
Jeeyun Ahn, Won Ryang Wee, Jin Hak Lee, Joon Young Hyon
SJR Q2Korean Journal of OphthalmologyOA

We report a case of vortex keratopathy in a patient treated with vandetanib for non-small cell lung cancer (NSCLC). A 44-year-old female who underwent two cycles of chemotherapy for NSCLC complained of visual blurring in both eyes after the initiation of vandetanib, an anti-epidermal growth factor receptor (EGFR) and anti-vascular endothelial growth factor receptor 2 protein tyrosine kinase inhibitor. On ophthalmic examination, visual acuities were 20 / 20 OU and, with the exception of diffuse v

HematologyMedicine
8
논문|인용수 26·2012
BILATERAL SAME-DAY INTRAVITREAL INJECTIONS USING A SINGLE VIAL AND MOLECULAR BACTERIAL SCREENING FOR SAFETY SURVEILLANCE
Se Joon Woo, Jeong Mo Han, Jeeyun Ahn, Jang Won Heo, Hyeong Gon Yu, Hum Chung, Junghan Song, Kyoung Un Park, Kyu Hyung Park
SJR Q1Retina

Bilateral same-day intravitreal injections drawn from a single vial using separate syringes or needles are well tolerated by patients, and its safety profile may be equivalent to unilateral injections. The bacterial molecular surveillance system using eubacterial PCR demonstrated the safety of bilateral same-day intravitreal injections and may be used for safety surveillance and for timely intervention of possible drug-related endophthalmitis.

OphthalmologyMedicine
9
논문|인용수 24·2016
Retinal thinning correlates with clinical severity in multiple system atrophy
Jeeyun Ahn, Jee‐Young Lee, Tae Wan Kim
SJR Q1Journal of Neurology
NeurologyMedicine
10
논문|인용수 17·2011
Ocular Findings in Cerebral Palsy Patients Undergoing Orthopedic Surgery
Se Joon Woo, Jeeyun Ahn, Moon Seok Park, Kyoung Min Lee, Dae Kyu Gwon, Jeong‐Min Hwang, Chin Youb Chung
SJR Q2Optometry and Vision Science

PURPOSE: To investigate the prevalence and clinical features of ocular abnormalities in patients with cerebral palsy (CP) and the association with gross motor function. METHODS: A complete ophthalmologic examination was performed in 88 consecutive patients with CP before and during orthopedic surgery in a tertiary hospital from July 2008 to March 2010. The prevalence and clinical features of ocular abnormalities and the association with gross motor function state were investigated. RESULTS: Seve

Pathology and Forensic MedicineMedicine
11
논문|인용수 7·2018
Efficacy of Gaze Photographs in Diagnosing Ocular Myasthenia Gravis
Jeeyun Ahn, Kyung Seok Park, Ji‐Soo Kim, Jeong‐Min Hwang
SJR Q2Journal of Clinical NeurologyOA

The diagnostic sensitivity was higher for gaze photographs than for the other tests applied to OMG patients.

NeurologyMedicine
12
논문|인용수 7·2021
The Associations of Obstructive Sleep Apnea and Eye Disorders: Potential Insights into Pathogenesis and Treatment
Jeeyun Ahn, Michael B. Gorin
SJR Q2Current Sleep Medicine ReportsOA

Abstract Purpose of Review Obstructive sleep apnea (OSA) patients are at significantly increased risks for cardiovascular and cerebrovascular morbidities. Recently, there has been heightened interest in the association of OSA with numerous ocular diseases and possible improvement of these conditions with the initiation of OSA treatment. We reviewed the current evidence with an emphasis on the overlapping pathogeneses of both diseases. Recent Findings Currently available literature points to a su

PhysiologyMedicine
13
논문|인용수 7·2020
Novel mutation in SLC4A7 gene causing autosomal recessive progressive rod-cone dystrophy
Jeeyun Ahn, John Chiang, Michael B. Gorin
SJR Q2Ophthalmic Genetics

We report a case of progressive rod-cone dystrophy caused by a novel mutation in <i>SLC4A7</i>, a gene coding the sodium bicarbonate cotransporter NBC3, underscoring the importance of ion homeostasis for photoreceptor function and maintenance.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
14
논문|인용수 6·2008
라식수술에서 미세각막절개도간의 각막절편 합병증 비교
안지윤, 권지원, 이상목, 위원량, 이진학, 한영근

목적: 라식수술에서 Hansatome Excellus와 Zyoptix XP 두 가지의 미세각막절개도를 사용시 발생한 각막절편 합병증의 빈도를 비교하고자 하였다. 대상과 방법: 라식수술 중 절편 제작시 Hansatome Excellus를 사용한 167명, 323안과 Zyoptix XP를 사용한 132명, 260안을 대상으로 수술 중과 수술 후의 각막절편 합병증의 발생빈도를 후향적으로 분석하였다. 결과: 수술 중 합병증은 Hansatome Excellus군이 2.7%로 Zyoptix XP군의 0.4%에 비해 유의하게 높았고(p<0.05), 수술 후 합병증은 Zyoptix XP군이 2.7%로 Hansatome Excellus군의 0.6%에 비해 높았으나 통계적으로 유의하지 않았고(p>0.05), 시력에 영향을 미칠만한 심각한 합병증은 두 군 모두에서 발생하지 않았다. 결론: Zyoptix XP는 수술 중 합병증의 발생이 Hansatome Excellus에 비해 유의하게 낮은 것으로 나타났

15
논문|인용수 4·2024
Changes in Choroidal Thickness of Healthy Children during Myopia Progression over 4 Years: Boramae Myopia Cohort Study Report 5
Jeong Hyun Lee, Joo Young Shin, Martha Kim, Kyoung Min Lee, Sohee Oh, Seok Hwan Kim, Ho-Kyung Choung, Jeeyun Ahn
SJR Q1Ophthalmology ScienceOA

Objective To investigate the relationship between choroidal thickness and myopia by analyzing change in choroidal thickness over time in children with myopia progression. Design Retrospective cohort study. Participants Children with myopia. Methods Spherical equivalent (SE), axial length, and choroidal thickness were measured every 2 years during course of 4 years in children with myopia enrolled in a prospective cohort study. Choroidal thickness was evaluated at 13 points on the ETDRS grid, and

EpidemiologyMedicine

대표 연구 분야

OphthalmologyRadiology, Nuclear Medicine and ImagingNeurologyMolecular BiologyPathology and Forensic MedicinePublic Health, Environmental and Occupational Health

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