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The incidence of AB in 2012 was 2.3% (number of AB patients per 100 positive blood culture patients) and the mortality rate in patients with clinically significant AB was 21.4%. In addition, AB was frequently noted in patients having malignancy and the survival rate of AB was significantly worse in patients who received inappropriate therapy compared with those underwent appropriate therapy.

Our data show that surveillance ≤ 6 months might be associated with early detection of HCC and improved survival in a hepatitis B endemic area.

Clostridium difficile is a significant nosocomial and community-acquired pathogen, and is the leading cause of antibiotic-induced diarrhea associated with high morbidity and mortality. Given that the treatment outcome depends on the severity of C. difficile infection (CDI), we aimed to establish an efficient method of assessing severity, and focused on the stool biomarker fecal calprotectin (FC). FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting th

The prevalence of obesity has increased alarmingly both worldwide and in Korea. This has also dramatically increased the prevalence of chronic obesity-associated diseases, including type 2 diabetes (T2D). Extensive studies on the molecular etiology of T2D have revealed several potential mechanisms by which obesity induces the development of insulin resistance and T2D. One of these is low-grade chronic inflammation. Studies hinting at the existence of this phenomenon were first published about 30

The objective of this study was to develop an inclusive fashion design (IFD) process using digital tools for educational purposes. The study consisted of three stages: development of IFD process prototypes 1 and 2 with different phases for incorporating diverse users’ information (before and after the ideation phase), conducting an experiment on ten undergraduate students using two types of IFD process prototypes, and analysing the IFD process prototypes through protocol analysis, statistical an

Dear Editor, In ALL, cytogenetic subgroups according to recurrent genetic abnormalities are used to classify patients for risk stratification and to introduce them to the proper therapeutic strategies—such as the use of tyrosine kinase inhibitors in the case of t(9;22)(q34;q11.2)/BCR-ABL1 fusion [1]. Therefore, the identification of genetic aberrations is clinically significant and crucial in understanding the leukemogenesis mechanisms. t(12;17)(p13;q11.2)/TAF15-ZNF384 rearrangement is a r

Clostridium difficile is a significant nosocomial and community-acquired pathogen, and is the leading cause of antibiotic-induced diarrhea associated with high morbidity and mortality. Given that the treatment outcome depends on the severity of C. difficile infection (CDI), we aimed to establish an efficient method of assessing severity, and focused on the stool biomarker fecal calprotectin (FC). FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting th

분노억제는 우울 증상과 같은 정서적 어려움과 더불어 다양한 신체화 및 신체적 문제와 연관되는 것으로보고되고 있으며 이와 같은 관계는 감정노동직군에서 관찰될 가능성이 특히 높다. 간호사와 같은 감정노동자들은 근무 환경에서 정서억제를 요구 받으며 가장 자주 경험되는 감정은 분노로 보고되고 있다. 이에 본연구에서는 간호사들을 대상으로 분노억제가 신체화 증상에 미치는 영향을 검증하고, 이러한 관계에서 우울 증상의 매개 효과를 살펴보고자 하였다. 이에 서울과 청주 지역에 소재한 2개 대학 병원에 6개월 이상근무하고 있는 138명의 간호사들을 대상으로 상태-특성 분노표 척도(STAXI-K), 한국판 우울 척도(CES-D) 및간이정신진단검사(SCL-90-R)를 실시하였다. 그 결과, 분노억제가 신체화 증상에 미치는 직접 효과가 유의하지 않았다. PROCESS macro를 통해 우울 증상의 매개효과를 검증한 결과, 분노억제와 신체화 증상 간의 관계에서 우울 증상의 간접효과가 통계적으로 유의한 것으

Chromium (III) oxide nanoparticles (NPs) have a wide range of industrial applications, particularly in the production of lithium-ion batteries; however, the toxicity of these NPs has not been studied extensively. The phytotoxicity and genotoxicity of chromium (III) oxide NPs have not been assessed, and only one study reported their cytotoxicity, underscoring the need to perform comprehensive toxicity studies on these NPs. Here, we showed that chromium (III) oxide NPs had no effect on germination

BACKGROUND: The germline mutations of DDX41, also known as DEAD box RNA helicase 41, have been found in about 1.5% of myeloid neoplasms (MNs). Development of MDS/AML is relatively common in germline DDX41 mutations. However, a variety of hematological malignancies (HMs) have been reported. CASE PRESENTATION: We report a novel case of bi-alleleic DDX41 mutations in B-cell lymphoblastic leukemia (B-ALL), with unusual location of DDX41 mutations. The gene expression profile (GEP) of Ph + B-ALL with

The majority of family physicians participating in this study were not in favor of the revised telehealth legislation. However, the majority of the participants had an intention to adopt telehealth to their practice and held clear opinion about practical aspects of telehealth.

Abstract This study aimed to address the diversity issue in fashion design education by developing two prototypes for Inclusive Fashion Design (IFD) education. The prototypes were constructed based on the 3C3R model of Project-Based Learning (PBL) and incorporated the Persona/Scenario (P/S) toolkit for IFD. Additionally, the study examined the effectiveness of the FEA (Function, Expressive, and Aesthetics) self-checklist and the P/S toolkit in the IFD process. The experiments involved two design