전승현 교수
Jeon Seung-hyun
경희대학교 비뇨의학과 · 의학
연구실 소개
전승현 교수의 연구실은 비만, 성기능 저하, 신장암 등 만성질환과 관련된 생물학적 메커니즘을 규명하고, 이를 바탕으로 새로운 치료 전략을 개발하는 데 초점을 맞추고 있습니다. 특히 남성 성기능 저하에 영향을 미치는 천연물 추출물의 효과와 신장 수술 중 신기능 보존을 위한 최적의 수술 기법 개발에 대한 연구가 두드러지며, 산화 스트레스와 항산화 효소의 역할에 대해서도 심층적인 분석을 수행하고 있습니다. 이와 함께 신장암 환자의 장기적 신기능 회복과 예후 요인 분석을 위한 다기관 임상 연구도 지속적으로 진행되고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We investigated the effects of tissue-cultured mountain ginseng extract (TMGE) on male patients with erectile dysfunction (ED). A double-blind, placebo-controlled study was conducted with 143 patients experiencing ED. Over the course of 8 weeks, one group took 1 000 mg of TMGE twice a day, a
Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does the study add? While laparoscopic radical nephrectomy (LRN) has been confirmed in various studies to be at least as efficacious as open radical nephrectomy (ORN) in terms of oncological control and more advantageous from the perspective of minimal invasiveness, very few studies have examined its feasibility and efficacy when applied to renal masses exceeding 7 cm in size, and even fewer involved res
The use of V-Loc sutures for renorrhaphy during LPN is safe and feasible and, in our series, significantly reduces WIT. Further studies are needed to corroborate these findings, but these results indicate a promising development in reducing WIT during minimally invasive partial nephrectomy.
Purpose: Intrinsic antioxidant enzymes (AOE) are essential for protection against potential cellular damage by reactive oxygen species (ROS), which affect many biological processes including carcinogenesis. The aim of the present study was to characterize the expression of antioxidant enzymes in human bladder cancer tissue and to evaluate the relationship with histopathological characteristics. Materials and Methods: Immunohistochemical stainingfor catalase, superoxide dismutase (SOD), and gluta
Five-year overall survival after radical nephrectomy in pT3N0M0 renal cell carcinoma is 35-50%. In light of immunotherapy, which has shown some activity in advanced diseases with increasing efficacy in limited metastatic invasion, we decided to explore the theoretical advantage of adjuvant immunotherapy in radically resected stage pT3N0M0 renal cell carcinoma. We studied several factors including tumor size, nuclear grade, mean nuclear area and expression of p53 protein to find out which factor
OBJECTIVES: To compare post-nephrectomy renal function between kidney donors and renal cell carcinoma patients, to evaluate trends in recovery, and to identify factors relevant to renal failure. METHODS: Patients who had radical or donor nephrectomy from four different institutions between 2003 and 2012 were reviewed. Propensity score matching was carried out and 79 patients were selected for each group. The estimated glomerular filtration rate was calculated using the Modification of Diet in Re
Our results suggest that 15 cases are needed for a novice surgeon to achieve competence in LRN. Surgical outcomes and morbidity can be improved once this learning curve has been overcome.
The prevalence of voiding dysfunction was 47.4% by the question of "do you usually experience a feeling of incomplete bladder emptying" from Korean version of PFDI (pelvic floor distress inventory), 33.7% by the value of less than 10th centile of peak flow rate of uroflowmetry by Liverpool nomogram, 20.2% by the cutoff values of less than 12 ml per second of maximum flow rate and greater than 25 cmH20 of detrusor pressure at maximum flow rate in the pressure flow study and 11.6% by the elevated
BACKGROUND: Robotic-assisted radical prostatectomy(RARP) is widely used to surgically treat of localized prostate cancer. Among RARP, retzius-sparing techniques(RS-RARP) are implemented through douglas pouch, not the existing conventional approach(C-RARP). We conducted an updated systematic review and meta-analysis including recent published papers. MATERIALS & METHODS: Systematic review was performed following the PRISMA guideline. PubMed, EMBASE, and Cochrane Library were searched up to August
Miniaturized percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for renal stones have been developed to overcome the invasive disadvantages of PCNL. We aimed to compare the therapeutic effect and safety of ultra-mini percutaneous nephrolithotomy (UMPCNL) and RIRS for renal stones using an updated systematic review and meta-analysis. We searched clinical trials comparing UMPCNL and RIRS for renal stones using the PubMed, EMBASE, Cochrane Library, and Google Scholar datab
An isolated unilocular renal hydatid cyst is very rare and to the best of our knowledge, no such case has been reported in the Korean literature. A 56 year old woman, who liked eating raw vegetables fertilized by dog feces, visited our department because of an incidentally found renal cyst. Ultrasonography and the computed tomography (CT) scan showed a ty-pical daughter cyst within the 6cm sized mother cyst. We performed retroperitoneal laparoscopic cyst marsupilaization after aspiration of the
PURPOSE: We investigated the effects of radical cystectomy and the prognostic factors that affect the survival of bladder cancer patients. MATERIALS AND METHODS: From 1979 to 2002, 59 patients with long-term follow up results of at least 2 years were enrolled in this study. Indications for surgery included muscle invasive bladder cancer and high-risk superficial bladder cancer. The cancer specific and recurrence free survival rates with respect to the possible prognostic factors were determined
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