정은철 교수
Jeong Eun-cheol
성균관대학교 의학과 · 의학
연구실 소개
정은철 교수의 연구실은 뇌혈관 질환, 특히 내경동맥에 발생하는 파열된 혈액 블러드 블리스터aneurysm(BBA)와 척추동맥·기저동맥의 분열 동맥류 등 치명적인 뇌출혈 유발 병변에 대한 최신 내과적 치료 기법을 중심으로 연구를 진행하고 있습니다. 특히 스텐트 보조 coil 씰링 및 스텐트 인 스텐트(SWS)와 같은 재건성 엔도빈질적 수술 기법의 임상적 적용과 장기적 결과 분석에 초점을 맞추고 있으며, 당뇨병과 청력 손실, 근육량과 심혈관 질환 간의 연관성 등 대사성 질환과 뇌혈관 질환의 상관관계에 대해서도 꾸준한 연구를 이어가고 있습니다. 특히 뇌혈관 질환의 조기 진단 및 개인 맞춤형 치료 전략 수립을 목표로 영상 유도 진단과 생체지표 분석을 융합한 연구를 수행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15OBJECT: Ruptured blood blister-like aneurysms (BBAs) of the internal carotid artery (ICA) are rare but carry a high rate of morbidity and mortality. Furthermore, BBAs are very difficult to treat surgically as well as endovascularly. The authors present their experience in treating BBAs with reconstructive endovascular methods. METHODS: Nine ruptured BBAs in 9 consecutive patients (2 men and 7 women; mean age 50 years, range 42-57 years) were treated using reconstructive endovascular methods betw
In order to assess underlying structural differences between the male and female corpus callosum, the fractional anisotropy and volume of the corpus callosum, and also its T1 signal intensity, were measured. The corpus callosum of the 15 normal women and 15 normal men was drawn on the mid-sagittal T1-weighted image, for determining its volume and signal intensity, and this region of interest was projected onto the coregistered fractional anisotropy image, in order to obtain the value for the cor
Background: To evaluate the association between diabetes mellitus (DM) and the development of incident hearing loss. Methods: Prospective cohort study was performed in 253 301 adults with normal hearing tests who participated in a regular health-screening exam between 2002 and 2014. The main exposure was the presence of DM at baseline, defined as a fasting serum glucose ≥ 126 mg/dL, a self-reported history of DM or current use of anti-diabetic medications. Pre-diabetes was defined as a fasting g
OBJECTIVE: Sarcopenia or low muscle mass is related to cardiovascular risk factors; however, the association between low muscle mass and subclinical atherosclerosis has been largely unexplored. We investigated whether muscle mass is related to coronary artery calcification (CAC) in a large sample of middle-aged asymptomatic adults. APPROACH AND RESULTS: We performed a cross-sectional study of 31 108 asymptomatic adults without cancer, diabetes mellitus, or known cardiovascular disease who underw
Ruptured blood blister-like aneurysms (BBAs) of the internal carotid artery (ICA) are potentially dangerous lesions because of the high risk of intraoperative bleeding associated with their wide fragile neck. The authors discuss cases in which BBAs were treated endovascularly during the chronic stage and report a case in which a ruptured BBA of the ICA was successfully treated in the acute phase with stent-assisted coil embolization and a subsequent stent-within-a-stent procedure.
OBJECT: A ruptured dissecting aneurysm of the vertebrobasilar artery (VBA-DA) is a well-known cause of acute subarachnoid hemorrhage (SAH) with a high rate of early rebleeding. Internal trapping of the parent artery, including the dissected segment, is one of the most reliable techniques to prevent rebleeding. However, for a ruptured VBA-DA not suitable for internal trapping, the optimal treatment method has not been well established. The authors describe their experience in treating ruptured VB
Objective: Reductions in the level of N -acetylaspartate within subcortical structures of patients with obsessive-compulsive disorder (OCD) have been reported in several studies. However, there have been, as yet, no reports regarding N -acetylaspartate levels in the prefrontal cortex of adult drug-naive OCD patients. The authors used proton magnetic resonance spectroscopic imaging ( 1 H-MRSI) to investigate regional N -acetylaspartate level abnormalities and changes after 12 weeks of pharmacothe
The 3D DRIVE is superior to the 3D bFFE in evaluation of the structures of the inner ear.
Intravascular embolization of fragments of indwelling intravascular diagnostic polyethylene catheter continues to occur. This causes many complications such as sepsis, thromboembolism, endocarditis and even perforation of cardiac chambers. The author experienced 3 cases of successful retrieval of intravascular iatrogenic catheter foreign bodies which were iocated in right pulmonary artery and inferior vena cava, using loop-snare technique.Percutaneous transluminal retrieval of catheter foreign b
Magnetic resonance imaging(MRI) of 47 patients with surgically confirmed lumbar disk herniation at 62 levels was studied retrospectively to evaluate the significance of MRI in diagnosis of lumbar disk herniation.Prolapsed type of lumbar disk herniation is 47 cases(76%). lumbar disk herniation at L4-L5 level is 33 cases(53 %) and posterolateral herniation is 54 cases(87%). 6 cases(10%) of lumbar disk herniation in MRI were not matched with operative findings, due to lumbar scoliosis(4 cases) and
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