정유숙 교수
Jeong Yoo-sook
성균관대학교 의학과 · 의학
연구실 소개
정유숙 교수의 연구실은 주로 주의력결핍과잉행동장애(ADHD)와 뇌신경질환을 가진 어린이 및 청소년의 정신건강과 발달적 문제를 중심으로 연구를 진행하고 있습니다. 특히 히포테라피(Hippotherapy)와 기수치료(Equine-Assisted Therapy)의 임상적 효과, 소아우울척도의 연령별 요인구조 분석, 그리고 ADHD의 유전적 기전 탐색을 통해 다학제적 접근을 시도하고 있습니다. 디지털 기반의 행동 분석 도구 개발을 통해 진단의 객관성과 정확성을 높이는 혁신적 연구도 함께 진행 중입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15This trial is promising, but further studies are required to evaluate the long-term clinical effectiveness of hippotherapy. The study is registered with ClinicalTrials.gov, number NCT 02482649.
This is the first study demonstrating that EAA/T is effective for improving core ADHD symptoms. On the basis of these results, EAA/T could be a viable treatment strategy as a part of a multimodal therapy for children with ADHD.
선행 연구에서 발달 수준에 따라 우울 증상의 표현 양상이 다르다고 하였다. 따라서 본 연구에서는 이런 견지에서 소아 우울 척도의 요인 구조를 임상 집단의 아동과 청소년 각각에서 검증하고자 하였다. 일반 아동(233명)과 청소년(369명)에서, 아동에비해 청소년의 우울 점수가 유의미하게 높았고, 아동은 청소년보다 식욕 및 수면 문제와 관련된 문항에서 유의미하게 높았으며 청소년은 부정적 자기상, 슬픈 기분, 학교 관련 문제 등에서 더 높게 나타났다. 그리고 탐색적 요인 분석을 실시하여 국내 아동 및 청소년의 요인구조를 살펴본 결과 아동은 3요인 상관 모형, 청소년은 4요인 상관 모형이 적절한 것으로 나타났다. 선행 연구들에서 제안된 요인구조들과 탐색적 요인 분석의 결과를 포함하여 대안 모형으로 설정하여 임상 집단의 아동(182명) 및 청소년(278명)을 대상으로 확인적 요인분석을 수행하였다. 그 결과, 국내 일반 아동 및 청소년의 요인구조로 아동은 3요인 상관 모형, 청소년은 4요인 상
BACKGROUND: Attention problems and decreased quality of life are frequently accompanied in Cerebral Palsy (CP), which can negatively affect rehabilitation of physical disability. However, the majority of affected children remain untreated in the aspects of attention or psychosocial factors. Equine-Assisted Activities and Therapies (EAAT) use horse as a therapeutic modality including grooming as well as mounted riding activities in which patients exercise and experience mounted stimulation. It is
Introduction: Diagnosis of Attention Deficit/Hyperactivity Disorder (ADHD) is based on clinical evaluation of symptoms by a psychiatrist, referencing results of psychological tests. When diagnosing ADHD, the child's behavior and functionality in real-life situations are critical components. However, direct observation by a clinician is often not feasible in practice. Therefore, such information is typically gathered from primary caregivers or teachers, which can introduce subjective elements. To
Recent studies showing the improvement of ADHD symptoms obtained with the highly selective noradrenergic reuptake inhibitor, atomoxetine, demonstrate that the noradrenergic system plays the role of pathophysiology in this disorder. It is revealed that the norepinephrine transporter gene (SLC6A2) is a possible candidate gene directly related to ADHD. To determine possible roles of the SLC6A2 as a susceptibility gene for ADHD, we performed the genetic association study for a functional -3081(A/T)
OBJECTIVE: Anxiety has been shown to influence functional impairment in patients with attention deficit hyperactivity disorder (ADHD). This study aimed to compare functional impairment in subjects with and without adult ADHD and to investigate the associations among trait anxiety, functional impairment, and ADHD symptom severity. Moreover, the effects of ADHD symptom subtypes on trait anxiety and functional impairment were also examined. METHODS: The sample included 209 adults between the ages o
OBJECTIVE: To examine the psychosocial outcomes and impact of attention problems in survivors of pediatric brain tumor. STUDY DESIGN: The survivors' cognitive functioning was measured using the Wechsler Intelligence Scale for Children. The Child Behavior Checklist-Attention Problems scale was used to screen for attention problems, and participants were classified as having attention problems (n=15) or normal attention (n=36). Psychosocial functioning was examined with the Korean Personality Rati
Our results suggest that aripiprazole is effective and generally tolerable in the treatment of irritability in Asian children and adolescents with autistic disorder. Further studies with larger sample sizes and longer treatment durations are required.
The Bruininks-Oseretsky Test of Motor Proficiency Second Edition (BOT-2) is the most common motor assessment in Korea. The BOT-2-Short Form (SF) is preferred over the complete form (CF) in settings with limited time. The present study aimed to assess the validity of the BOT-2 SF in Korean school-age children. First, we verified that the BOT-2 SF reflects developmental changes in motor skills. Second, we compared the BOT-2 SF scores to those of the BOT-2 CF. A total of 283 Korean school-age child
Objective The objective of this study was to compare quantitative electroencephalography (Q-EEG) characteristics of children with Attention-deficit/hyperactivity disorder (ADHD), taking into account the presence of a comorbidity for anxiety disorder. It also sought to investigate the impact of comorbid anxiety on the Q-EEG heterogeneity of children with ADHD. Method A total of 141 children with ADHD but without comorbid anxiety (ADHD-Only), 25 children with a comorbidity for anxiety disorder (AD
AIM: This study examined the efficacy of AST-001 for the core symptoms of autism spectrum disorder (ASD) in children. METHODS: This phase 2 clinical trial consisted of a 12-week placebo-controlled main study, a 12-week extension, and a 12-week follow-up in children aged 2 to 11 years with ASD. The participants were randomized in a 1:1:1 ratio to a high-dose, low-dose, or placebo-to-high-dose control group during the main study. The placebo-to-high-dose control group received placebo during the m
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