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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntibacterial activity of some essential oil components against five foodborne pathogensJeongmok Kim, Maurice R. Marshall, and Cheng-i WeiCite this: J. Agric. Food Chem. 1995, 43, 11, 2839–2845Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/jf00059a013https://doi.org/10.1021/jf00059a013research-articleACS PublicationsRequest reuse permissionsArticle

ABSTRACT Carvacrol, citral and geraniol showed potent antibacterial activity against Salmonella typhimurium and its rifampicin‐resistant (Rif R ) strain as determined in txyptic soy broth and by zone of inhibition on agar‐based medium. Carvacrol had the most potent bactericidal activity, with minimum inhibitory and bactericidal concentrations (MIC and MBC) of 250 μg/mL for both tester strains. When tested at 0.5, 1.5 and 3.0% in 1% Tween 20 for bactericidal activity against Rif R ‐ S. typhimuriu

Rgs2, a regulator of G proteins, lowers blood pressure by decreasing signaling through Gαq. Human patients expressing Met-Leu-Rgs2 (ML-Rgs2) or Met-Arg-Rgs2 (MR-Rgs2) are hypertensive relative to people expressing wild-type Met-Gln-Rgs2 (MQ-Rgs2). We found that wild-type MQ-Rgs2 and its mutant, MR-Rgs2, were destroyed by the Ac/N-end rule pathway, which recognizes N(α)-terminally acetylated (Nt-acetylated) proteins. The shortest-lived mutant, ML-Rgs2, was targeted by both the Ac/N-end rule and A

In bacteria, nascent proteins bear the pretranslationally generated N-terminal (Nt) formyl-methionine (fMet) residue. Nt-fMet of bacterial proteins is a degradation signal, termed fMet/N-degron. By contrast, proteins synthesized by cytosolic ribosomes of eukaryotes were presumed to bear unformylated Nt-Met. Here we found that the yeast formyltransferase Fmt1, although imported into mitochondria, could also produce Nt-formylated proteins in the cytosol. Nt-formylated proteins were strongly up-reg

Although resistance of Helicobacter pylori to clarithromycin is a major cause of failure of eradication therapies, little information is available regarding gene mutations of clarithromycin-resistant primary and secondary H. pylori isolates in Korea. In the present study, we examined gene mutations of H. pylori 23S rRNA responsible for resistance to clarithromycin. DNA sequences of the 23S rRNA gene in 21 primary clarithromycin-resistant and 64 secondary clarithromycin-resistant strains were det

The use of chlorine dioxide (ClO(2)) as a potential substitute for aqueous chlorine to improve the quality of seafood products has not been approved by regulatory agencies due to health concerns related to the production of chlorite (ClO(2)(-)) and chlorate (ClO(3)(-)) as well as possible mutagenic/carcinogenic reaction products. Cubes of Atlantic salmon (Salmo salar) and red grouper (Epinephelus morio) were treated with 20 or 200 ppm aqueous chlorine or ClO(2) solutions for 5 min, and extracts

Extensive progress in understanding the molecular mechanisms of cancer growth and proliferation has led to the remarkable development of drugs that target cancer-driving molecules. Most target molecules are proteins such as kinases and kinase-associated receptors, which have enzymatic activities needed for the signaling cascades of cells. The small molecule inhibitors for these target molecules greatly improved therapeutic efficacy and lowered the systemic toxicity in cancer therapies. However,

Background/Aims: Development of antibiotic resistance is a significant clinical problem in the eradication of H. pylori. To select an appropriate regimen, systematic information on antibiotic resistance is mandatory. Thus, we investigated the distribution of minimal inhibitory concentration (MIC) and evaluated the antibiotic resistance of H. pylori isolates from Korean patients in 2003. Methods: The susceptibility of 65 isolates obtained in 2003 to amoxicillin, clarithromycin, metronidazole, tet

The distribution of minimal inhibitory concentrations (MIC) for amoxicillin, clarithromycin, metronidazole, tetracycline, azithromycin, and fluoroquinolone (ciprofloxacin, levofloxacin, and moxifloxacin) have shifted to higher concentrations from 1987 to 2003 in Helicobacter pylori (H. pylori) strains isolated from Korean patients. MIC values of secondary isolates were higher than those of primary isolates. Of treatment-failure patients, 16.4% showed mixed infections with both antibiotic-suscept

ABSTRACT The effect of chlorine dioxide (ClO 2 ) treatment on nutrients of seafood was studied using Atlantic salmon ( Salmo salar ) and red grouper ( Epinephelus morio ) with five volumes (1:5, w/v) of aqueous ClO 2 at 20, 40,100, and 200 ppm ClO 2 in 3.5% brine for 5 min. Compared to nontreated controls, treatment of salmon and red grouper with ClO 2 solutions in brine did not significantly change the contents of protein, fat, moisture, niacin, calcium, iron, phosphorus, or potassium. However,

"Crosstalk between the Arg/N-end and Ac/N-end rule." Cell Cycle, 13(9), pp. 1366–1367Keywords:: ubiquitinproteolysisacetylationmethionineN-end ruleUbr1degronThis article is related to:

Bacillus anthracis is a causative agent of anthrax.lethal factor (LF), and edema factor (EF), in which the PA is acentral mediator for the delivery of the two enzymatic moietiesLF and EF. Therefore, the PA has ben an attractive target inthe prevention and vacinization for anthrax toxin. Recently,it has been reported that the molecule consisting of multiplecopies of PA-binding peptide, covalently linked to a flexiblepolymer backbone, blocked intoxification of anthrax toxin inan animal model. In t

Abstract Chlorine dioxide (CIO 2 ) has been explored as a potential substitute for aqueous chlorine to clean seafood products. In an attempt to understand the interaction of CIO 2 with organic compounds, duplicate fillets of Atlantic salmon ( Salmo salar ) and red grouper ( Epinephelus morio ) were treated for 5 min with freshly prepared aqueous CIO 2 at 20, 40, 100, and 200 ppm total available CIO 2 in 3.5% brine. Thiobarbituric acid (TBA) values and fatty acid composition were determined. CIO

Coupling of spin and heat currents enables the spin Nernst effect, the thermal generation of spin currents in nonmagnets that have strong spin-orbit interaction. Analogous to the spin Hall effect that electrically generates spin currents and associated electrical spin-orbit torques (SOTs), the spin Nernst effect can exert thermal SOTs on an adjacent magnetic layer and control the magnetization direction. Here, the thermal SOT caused by the spin Nernst effect is experimentally demonstrated in W/C