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김지회 교수

Ji Hoi Kim

서울대학교 산부인과 · 의학

연구실 소개

김지회 교수의 연구실은 신경과학과 종양학 분야에서 다학제적 연구를 수행하고 있습니다. 뇌 영상 기반의 체질적 변화 분석을 통해 편두통 환자의 뇌 구조적 변화와 대사 변화를 규명하고 있으며, 동시에 면역조절 단백질 IL-32의 종양 억제 기전을 규명하는 데에도 주력하고 있습니다. 특히, 편두통의 만성화 요인과 암 생물학적 기전을 뇌 구조와 분자 생물학적 기전을 연결해 연구하고 있습니다.

편두통뇌 구조 변화IL-32대사 변화종양 억제

연구 현황

논문 수
50
총 인용 수
821
최근 5년 논문
13
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
13총합
2019
2020
2021
2023
2025
5개년 연도별 피인용 수
12총합
20192020202120232025

주요 논문

15
1
논문|인용수 327·2008
Regional Grey Matter Changes in Patients With Migraine: A Voxel-Based Morphometry Study
JH Kim, S-I Suh, HY Seol, Kyungmi Oh, W-K Seo, S-W Yu, K.-W. Park, S-B Koh
SJR Q1Cephalalgia

We used voxel-based morphometry (VBM) to compare grey matter volume (GMV) between 20 migraine patients (five with aura and 15 without aura) with normal conventional magnetic resonance imaging findings and 33 healthy controls matched for age and sex. A separate analysis was also performed to delineate a possible correlation between the GMV changes and the headache duration or lifetime headache frequency. When compared with controls, migraine patients had significant GMV reductions in the bilatera

Psychiatry and Mental healthMedicine
2
논문|인용수 117·2009
Interictal Metabolic Changes in Episodic Migraine: A Voxel-Based FDG-PET Study
JH Kim, S Kim, S-I Suh, S-B Koh, K‐W Park, Kyungmi Oh
SJR Q1Cephalalgia

Whereas there are many H(2)(15)O-positron emission tomography (PET) studies demonstrating neuronal activation during acute migraine attacks, little information is available on the interictal (headache-free period) glucose metabolic changes in migraine. We therefore conducted voxel-based statistical parametric mapping analysis of (18)F-fluorodeoxyglucose-PET to evaluate interictal metabolic differences between 20 episodic migraine patients (four with aura; three men; mean age 34.0 +/- 6.4 years)

Psychiatry and Mental healthMedicine
3
논문|인용수 104·2010
Outcomes after radical hysterectomy in patients with early-stage adenocarcinoma of uterine cervix
J-Y Park, Do Young ‍Kim, JH Kim, Y-M Kim, Y-T Kim, JH Nam
SJR Q1British Journal of CancerOA

BACKGROUND: To determine the prognostic factors and treatment outcomes of patients with early-stage adenocarcinoma (AdCa) of uterine cervix who underwent radical hysterectomy (RH). METHODS: Patients with early-stage squamous cell carcinoma (SCCa) of the uterine cervix who underwent RH were compared with patients with AdCa by multivariate analysis. RESULTS: A total of 1218 patients were eligible, of which 996 (81.8%) had SCCa and 222 (18.2%) had AdCa. In multivariate analysis, parametrial involve

Obstetrics and GynecologyMedicine
4
논문|인용수 92·2011
IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals
Jimin Oh, M.-C. Cho, JH Kim, S Y Lee, H J Kim, E S Park, J O Ban, J-W Kang, D-H Lee, J-H Shim, Sang‐Bae Han, Dong Cheul Moon
SJR Q1OncogeneOA

Several studies have shown physiological functions of interleukin (IL)-32, a novel cytokine. However, the role of IL-32 in cancer development has not been reported. In this study, we showed that IL-32γ inhibited tumor growth in IL-32γ-overexpressing transgenic mice inoculated with melanoma as well as colon tumor growth in xenograft nude mice inoculated with IL-32γ-transfected colon cancer cells (SW620). The inhibitory effect of IL-32γ on tumor growth was associated with the inhibition of constit

OncologyMedicine
5
논문|인용수 43·2013
Characterization of GFRα‐1‐Positive and GFRα‐1‐Negative Spermatogonia in Neonatal Pig Testis
Kyung Ho Lee, Won‐Young Lee, JH Kim, MJ Yoon, NH Kim, JH Kim, SJ Uhm, Do‐Hyung Kim, HJ Chung, Hyuk Song
SJR Q2Reproduction in Domestic Animals

Type A spermatogonia, including spermatogonial stem cells, are primary cells that maintain spermatogenesis and produce spermatozoa. Many spermatogonial markers have been reported in rodents. However, few markers have been identified in pig spermatogonia. Despite the lack of information, it is necessary to separate pure spermatogonial cells from whole testicular cells to understand the mechanism of spermatogenic meiosis and to establish spermatogonial stem cells for further biotechnological studi

Reproductive MedicineMedicine
6
논문|인용수 39·2006
Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3β expression
Yanji Xu, Kim Hs, Young Ji Joo, Yiseul Choi, K-A Chang, C H Park, K. S. Shin, Sung‐Hoon Kim, Y-H Cheon, T-K Baik, JH Kim, Y-H Suh
SJR Q1Cell Death and Differentiation
PhysiologyMedicine
7
논문|인용수 35·2012
Diagnostic sensitivity of culture and drug resistance patterns in Korean patients with intestinal tuberculosis
Byong Duk Ye, S-K. Yang, Donghoi Kim, Tae Sun Shim, Sung‐Han Kim, M.-N. Kim, Y. J. Lee, Hee Kyong Na, Seong Ho Park, Dong‐Hoon Yang, Kwang J. Kim, J-S. Byeon
SJR Q1The International Journal of Tuberculosis and Lung Disease

Culture of colonoscopic biopsy specimens shows substantial diagnostic sensitivity; the frequency of MDR-TB is higher in previously treated cases than in new cases.

Infectious DiseasesMedicine
8
논문|인용수 15·2012
Infiltrating Foxp3+ Regulatory T cells and Histopathological Features in Canine Classical and Spermatocytic Seminomas
JH Kim, SK Chon, Im Ks, NH Kim, KW Cho, Jung‐Hyang Sur
SJR Q2Reproduction in Domestic Animals

In humans, regulatory T (T reg) cells are known to play a critical role in both the regulation of immune homoeostasis and the progression of cancer. However, there is little information about the identification, characterization and the function of T reg cells in canine tumours. We identified T reg cells in 28 canine seminoma samples using a Forkhead box P3 (Foxp3) antibody and investigated the relationship between T reg cell infiltration and histopathological features of classical and spermatoc

ImmunologyImmunology and Microbiology
9
논문|인용수 14·2014
Angiographic evaluation of hepatic arterial injury after cisplatin and Gelfoam–based transcatheter arterial chemoembolization for hepatocellular carcinoma in a 205 patient cohort during a 6-year follow-up
Chong Hyun Suh, Ji Hoon Shin, H.M. Yoon, Hyun‐Ki Yoon, G-Y Ko, Do-Hyeon Gwon, JH Kim, K-B Sung
SJR Q1British Journal of RadiologyOA

In patients who underwent three or more sessions of cisplatin and Gelfoam-based TACE, the overall incidence of HAI was 24.4%, and increasing TACE causes increased incidence of HAI.

HepatologyMedicine
10
논문|인용수 7·2007
Long-term follow-up of porcine male germ cells transplanted into mouse testes
Y-J Choi, J-K. Park, Ming‐Shyue Lee, Jung‐Mo Ahn, K-C. Hwang, Hyuk Song, JH Kim
SJR Q4Zygote

This study investigated the effect of increased phylogenetic distance on the outcome of spermatogonial transplantation, with porcine donors and mice recipients. It was designed to develop a technique for detecting foreign donor cells in recipient animals. Porcine male germ cells were harvested from postnatal male testes and incubated with the lipophilic membrane dye PKH-26. For transplantation, approximately 10(6) PKH-26-labelled porcine male germ cells were injected into the efferent ducts of m

Reproductive MedicineMedicine
11
논문|인용수 6·2023
655O Phase Ib study of cofetuzumab pelidotin, an anti-PTK7 antibody-drug conjugate, in patients with PTK7-expressing recurrent non-small cell lung cancer (rNSCLC)
Byoung Chul Cho, Melissa L. Johnson, Jair Bar, Eric Schaefer, Kiyotaka Yoh, Alona Zer, M.T. Moskovitz, SH Lee, Víctor Moreno, Maria J. de Miguel, Yusuke Okuma, JH Kim
SJR Q1Annals of OncologyOA
OncologyMedicine
12
논문|인용수 5·2017
SAT0693 Serum uric acid levels and hormone replacement therapy type: a retrospective case-control study of postmenopausal women
JH Jung, JH Kim, Young Ho Lee, Gwan Gyu Song, SJ Choi
SJR Q1Annals of the Rheumatic DiseasesOA
NephrologyMedicine
13
논문|인용수 3·2017
FRI0311 Endovascular intervention versus surgery in patients with takayasu arteritis: a meta-analysis
JH Jung, Gwan Gyu Song, SJ Choi, Young Ho Lee, JH Kim
SJR Q1Annals of the Rheumatic DiseasesOA
Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 3·2006
Russell body gastritis associated with Helicobacter pylori infection: A case report
Soya Paik, Sang‐Ha Kim, JH Kim, Woo Ick Yang, Y C Lee

An unusual and rare gastric mucosal lesion histologically consisting of a localised accumulation of bodies and body-containing plasma cells, the so-called Mott cells, has been recognised only recently and termed as Russell body gastritis. This lesion, despite its densely monomorphous appearance is easily confirmed to be non-neoplastic by its polyclonal immunoreactive pattern to immunoglobulin light chains. However, the aetiology of body gastritis is controversial and hence the optimal treatment

GeneticsMedicine
15
논문|인용수 3·2018
A 24-week clevudine monotherapy produced profound on-treatment viral suppression as well as sustained viral suppression and normalization of aminotransferase levels for 24 weeks off-treatment in HBeAg(+) chronic hepatitis B patients.
Yoo Bc, JH Kim, KS Lee, Tae Hee Kim, SW Paik, SH Ryu, J-Y. Han, M Cho, SG Hwang, Kim Bi, Yung Seng Lee, HC Kim
SJR Q1Hepatology
EpidemiologyMedicine

대표 연구 분야

Pulmonary and Respiratory MedicineObstetrics and GynecologySurgeryEpidemiologyPathology and Forensic MedicineOncology

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