Skip to main content

이진구 교수

Jin Goo Lee

연세대학교 흉부외과 · 의학

연구실 소개

이진구 교수의 연구실은 주로 폐암, 간세포생식세포암 등 암의 전이 및 치료 내성 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 특히 자가포식(autophagy)과 저산소 상태와 연관된 신호전달 경로가 화학요법 내성에 미치는 영향을 연구하며, 수술적 치료 후 예후에 영향을 미치는 해부학적 및 분자적 요인을 분석하고 있습니다. 또한 이식 수술(예: 폐배열술)과 같은 고위험 수술에서의 생존율 향상 전략과 병변의 해부학적 특성 분석을 통해 개인화된 치료 접근법을 모색하고 있습니다.

자가포식암 전이예후 인자수술 치료저산소 상태

연구 현황

논문 수
267
총 인용 수
3,702
최근 5년 논문
67
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
67총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
319총합
20222023202420252026

주요 논문

15
1
논문|인용수 103·2007
Number of Metastatic Lymph Nodes in Resected Non–Small Cell Lung Cancer Predicts Patient Survival
Jin Gu Lee, Chang Young Lee, In Kyu Park, Dae Joon Kim, Sung Yong Park, Kil Dong Kim, Kyung Soo Chung
SJR Q1The Annals of Thoracic SurgeryOA
Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 92·2009
Pulmonary aspergilloma: Analysis of prognosis in relation to symptoms and treatment
Jin Gu Lee, Chang Young Lee, In Kyu Park, Dae Joon Kim, Joon Chang, Soon Il Kim, Kyung Soo Chung
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
Infectious DiseasesMedicine
3
논문|인용수 73·2015
Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions
Jin Gu Lee, Ju Hye Shin, Hyo Sup Shim, Chang Young Lee, Dae Joon Kim, Young Sam Kim, Kyung Soo Chung
SJR Q1Respiratory ResearchOA

Autophagy may play an important role in acquiring resistance to chemotherapy in lung cancer and hypoxia related pathway seems to be involved in autophagy induction.

EpidemiologyMedicine
4
논문|인용수 60·2008
Preoperative C-reactive protein levels are associated with tumor size and lymphovascular invasion in resected non-small cell lung cancer
Jin Gu Lee, Byoung Chul Cho, Mi Kyung Bae, Chang Young Lee, In Kyu Park, Dae Joon Kim, Song Vogue Ahn, Kyung Soo Chung
SJR Q1Lung CancerOA
OncologyMedicine
5
논문|인용수 43·2016
Transition to routine use of venoarterial extracorporeal oxygenation during lung transplantation could improve early outcomes
Woo Sik Yu, Hyo Chae Paik, Seokjin Haam, Chang Young Lee, Kyung Sik Nam, Hee Suk Jung, Young Woo, Jee Won Shu, Jin Gu Lee
SJR Q2Journal of Thoracic DiseaseOA

Routine use of ECMO during LTx could improve early outcome and postoperative lung function without increased extracorporeal-related complication such as vascular and neurologic complications.

SurgeryMedicine
6
논문|인용수 40·2011
Thoracoscopic Lobectomy Is Associated With Superior Compliance With Adjuvant Chemotherapy in Lung Cancer
Jin Gu Lee, Byoung Chul Cho, Mi Kyung Bae, Chang Young Lee, In Kyu Park, Dae Joon Kim, Kyung Young Chung
SJR Q1The Annals of Thoracic SurgeryOA
Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 37·2010
Surgical resection for pulmonary metastasis from hepatocellular carcinoma: Analysis of prognosis in relation to primary control
Chang Young Lee, Mi Kyung Bae, In Kyu Park, Dae Joon Kim, Jin Gu Lee, Jin Sub Choi, Kwang‐Hyub Han, Kyung Soo Chung
SJR Q1Journal of Surgical OncologyOA

BACKGROUND: Advances in local treatments for hepatocellular carcinoma (HCC) have seen better prognosis. There were few studies on surgery for pulmonary metastasis from HCC controlled by local treatment. This study was conducted to analyze prognostic factors after surgery for pulmonary metastasis from HCC. METHODS: We reviewed 32 patients who underwent surgery for pulmonary metastasis from HCC and analyzed prognostic factors. RESULTS: HCC was controlled by surgery in 16 patients and by local trea

HepatologyMedicine
8
논문|인용수 34·2012
Napsin A is an independent prognostic factor in surgically resected adenocarcinoma of the lung
Jin Gu Lee, Sewha Kim, Hyo Sup Shim
SJR Q1Lung Cancer
Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 33·2018
Establishment of a platform of non-small-cell lung cancer patient-derived xenografts with clinical and genomic annotation
Han Na Kang, Jae Woo Choi, Hyo Sup Shim, Jinna Kim, Dae Joon Kim, Chang Young Lee, Min Hee Hong, Sung Yong Park, A‐Young Park, Eun Joo Shin, Seo Yoon Lee, Kyoung‐Ho Pyo
SJR Q1Lung CancerOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
10
논문|인용수 28·2016
Sarcopenia of thoracic muscle mass is not a risk factor for survival in lung transplant recipients
Seokkee Lee, Hyo Chae Paik, Seokjin Haam, Chang Young Lee, Kyung Sik Nam, Hee Suk Jung, Young Woo, Jee Won Shu, Jin Gu Lee
SJR Q2Journal of Thoracic DiseaseOA

Although patients with thoracic sarcopenia seem to require a longer post-operative recovery time after LTx, this does not compromise their early outcomes. By contrast, patients with larger thoracic muscle volume (Q4) showed poorer survival times.

SurgeryMedicine
11
논문|인용수 26·2008
Non-small cell lung cancer with ipsilateral pulmonary metastases: prognosis analysis and staging assessment☆☆☆
Jin Gu Lee, Chang Young Lee, Dae Joon Kim, Kyung Soo Chung, In Kyu Park
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

OBJECTIVE: Although designated as T4 or M1 in the current TNM classification system revised in 1997, non-small cell lung cancer with ipsilateral pulmonary metastases is treated as a locally advanced disease and reported survival rates are relatively good. We intended to analyze the prognosis of ipsilateral pulmonary metastases and validate current TNM classification system. METHODS: Data of 1213 surgically treated patients with non-small cell lung cancer from January 1990 to December 2004 were r

Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 25·2016
Pulmonary fissure development is a prognostic factor for patients with resected stage I lung adenocarcinoma
Seokkee Lee, Jin Gu Lee, Chang Young Lee, Dae Joon Kim, Kyung Soo Chung
SJR Q1Journal of Surgical OncologyOA

The overall survival of patients with resected stage I adenocarcinoma was adversely affected by incomplete fissure development. J. Surg. Oncol. 2016;114:848-852. © 2016 2016 Wiley Periodicals, Inc.

Pulmonary and Respiratory MedicineMedicine
13
논문|인용수 24·2008
The Prognostic Significance of Multiple Station N2 in Patients with Surgically Resected Stage IIIA N2 Non-small Cell Lung Cancer
Jin Gu Lee, Chang Young Lee, In Kyu Park, Dae Joon Kim, Sang-Ho Cho, Kil Dong Kim, Kyung Soo Chung
SJR Q2Journal of Korean Medical ScienceOA

Mediastinal (N2) lymph node involvement is heterogeneous with huge variation in the extent and grouped together under stage IIIA. However, they showed a different survival even in the same stage. We tried to determine the prognostic implication of the multiple station N2 lymph node metastasis in stage IIIA N2 non-small cell lung cancer (NSCLC). The survival of stage IIIA N2 was analyzed according to the number of N2 station and their survival was compared with that of stage IIIB. In stage IIIA N

Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 22·2008
Validity of International Association for the Study of Lung Cancer Proposals for the Revision of N Descriptors in Lung Cancer
Jin Gu Lee, Chang Young Lee, Mi Kyung Bae, In Kyu Park, Dae Joon Kim, Kil Dong Kim, Kyung Soo Chung
SJR Q1Journal of Thoracic OncologyOA
Pulmonary and Respiratory MedicineMedicine
15
논문|인용수 19·2018
Prognostic factors for resected non‐small cell lung cancer in patients with type 2 diabetes mellitus
Woo Sik Yu, Chang Young Lee, Sung Yong Park, Jee Won Suh, Kyoung Shik Narm, Dae Joon Kim, Kyung Soo Chung, Jin Gu Lee
SJR Q1Journal of Surgical OncologyOA

BACKGROUND: For diabetic patients with lung cancer, blood glucose levels and medications such as metformin and statins may influence survival. OBJECTIVES: This study aimed to determine prognostic survival factors for diabetic patients with resected non-small cell lung cancer. PATIENTS AND METHODS: Between January 2005 and December 2013, 301 patients with type 2 diabetes mellitus who underwent curative resection for non-small cell lung cancer were identified and reviewed retrospectively. RESULTS:

Cancer ResearchBiochemistry, Genetics and Molecular Biology

대표 연구 분야

SurgeryPulmonary and Respiratory MedicineNeurologyMolecular BiologyOncologyEpidemiology

이진구 교수의 연구를 Nubint에서 더 깊이 살펴보세요

이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.