김정희 교수
Jin-Hyuk Kim
한양대학교 생리학과 · 의학
연구실 소개
김정희 교수의 연구실은 주로 환경요인과 건강 간의 상관관계를 중심으로 연구를 진행하고 있습니다. 특히 실내 공기 오염물질(예: 휘발성 유기화합물, 포름알데히드), 미세먼지 등 환경 오염이 아토피성 피부염, 천식, 알레르기성 비염과 같은 알레르기성 질환에 미치는 영향을 분석하고 있으며, 어린이 및 특정 직업군(예: 객실승무원)을 대상으로 한 생활환경과 건강의 관계를 다룹니다. 이와 함께 약물 중단 후 혈소판 기능 회복 시기나 생체모니터링 기반의 노출 평가 기법 등 임상적·환경의학적 접근도 함께 연구하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15INTRODUCTION: Inappropriate antiplatelet therapy discontinuation increases the risk of thrombotic complications and bleeding after dental procedures. To determine the platelet reactivity recovery time after aspirin withdrawal in vivo, our study was conducted in patients with low-risk cardiovascular disease who can stop aspirin administration following the guidelines stipulated by the American College of Chest Physicians. The time it takes for platelet activity to normalize and the diagnostic acc
The increasing prevalence of atopic dermatitis (AD) is associated with variations in indoor environments. In Korea, many inner walls of homes are covered with wallpaper: such walls emit indoor air pollutants, including volatile organic compounds (VOCs) and formaldehyde. This randomized, double-blind study investigated the effects of wallpaper on indoor air quality and AD. Thirty-one children (aged three to eight years) with moderate AD were assigned to environmentally-friendly (EF) and polyvinyl
It has been reported that the particulate matter under 10 microm (PM10) has deleterious effects on respiratory health. The purpose of this study was to assess the influence of PM10 upon normal children's lung function. The subjects were 368 middle school students in two areas of Incheon Metropolitan City. One (Incheon) is in the central city and the other (Ganghwa) is in the suburbs. Air pollution data in the vicinities of two participating schools were obtained from monthly report of air qualit
본 연구는 객실승무원의 직무 환경에 맞게 구성된 7가지 독립요인(팀 내 악습, 갈등 관계, 역할 갈등, 모호성, 과부하, 스케줄 유연성, 징계)들이 직장 생활의 질과 삶에 질에 미치는 영향 관계를 분석하고자 한다. 본 연구는 국내 대형 항공사에 재직 중인 객실승무원 250명을 대상으로 설문조사를 실시하여 배포된 설문지 중 236개의 자료를 수집하였다. 이 중 불성실한 응답 15개를 제외한 총 221 부의 유효 표본을 확보하여 SPSS Statistics 23.0 통계패키지 프로그램을 통해 최종 분석에 활용하였다. 분석 결과, 관계적 요인에서 팀 내 관계 갈등이 삶의 질에 유의한 영향을 미치는 것으로 나타났다. 업무적 요인에서는 역할 모호성이 삶의 질에 유의한 영향을 미치는 것으로 나타났으며, 제도적요인에서는 스케줄 유연성과 징계, 두 가지 모두 삶의 질에 유의한 영향을 미치는 것으로 분석되었다. 마지막으로 직장 생활의 질이 삶의 질에 유의한 영향을 미치는 것으로 나타났다. 따라서 본
Epidemiologic studies have suggested the association between environmental exposure to volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs) and the increased risk of incurring asthma. Yet there is little data regarding the relationship between personal exposure to air pollution and the incidence of asthma in children. This study was designed to evaluate the effect of exposure to air pollution on children with asthma by using exposure biomarkers. We assessed the exposure
Background: The aims of this study were to investigate the prevalence of allergic rhinitis (AR) and the accuracy of the International Study of Asthma and Allergies in Childhood (ISAAC) questions for diagnosis of AR, in Korean children. Methods: Students that participated in an allergic disease prevalence survey in 2010–2017 were evaluated (n = 18,425) using questionnaires and a skin prick test (SPT). Age−stratified (5−7, 8−10, 11−13, 14−16 years) prevalence of four rhinitis questions, accuracy o
An apple (Malus × domestica Borkh.) core collection was established using 19 SSR markers in 1,344 apple germplasm samples using the PowerCore program. For this, 166 accessions were selected using a heuristic strategy, accounting for about 12.4% of the entire collection. The core collection had an allelic loci retention ratio of 100%, and no significant differences were observed in the number of alleles, Shannon’s information index, observed heterozygosity, expected heterozygosity, major allele f
During the transsphenoidal approach (TSA), the proper sellar floor reconstruction plays an important role in the surgical results. The authors have evaluated the usefulness of a silicone as a substitute for bone splint in sellar floor reconstruction. Silicone plates were used in 10 patients who had 7 pituitary adenomas, 2 Rathke's cleft cysts, and 1 metastatic tumor. Among the ten cases, seven underwent standard TSAs and three received extended TSAs. The silicone plate was cut to a size slightly
PURPOSE: To develop a novel, simplified method for correcting the ischemic index of nonperfused areas in diabetic retinopathy (DR). METHODS: We performed a retrospective review of 103 eyes with naive DR that underwent ultra-widefield angiography (UWFA) over a year. UWFAs were graded according to the quantity of retinal non-perfusion, and uncorrected ischemic index (UII) and corrected ischemic index (CII) were calculated using a simplified, novel method. RESULTS: The average differences between U
Atopic dermatitis (AD) is a lifelong disease that markedly impairs quality of life. AD is considered a starting point of the "atopic march," which begins at a young age and may progress to systemic allergic diseases. Moreover, it is strongly associated with comorbid allergic and inflammatory diseases including arthritis and inflammatory bowel disease. Understanding the pathogenesis of AD is essential for the development of targeted therapies. Epidermal barrier dysfunction, immune deviation towar
The developed questionnaire is essential and practical for assessing discomfort related to the symptoms felt by Korean children with allergic rhinitis.
INTRODUCTION: The increasing popularity of trekking in alpine regions has drawn attention to high altitude-associated health concerns. CASE REPORT: Here, we report a case of cerebral venous infarction as a consequence of a hypercoagulable state induced by secondary polycythemia as an adaptation to high altitude. CONCLUSIONS: When patients present focal neurological symptoms such as hemiparesis in addition to symptoms of acute mountain sickness or high-altitude cerebral edema such as headache, na
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