정진욱 교수
Jin Wook Jeoung
서울대학교 안과 · 의학
연구실 소개
정진욱 교수의 연구실은 망막 신경절층(GCIPL)과 시신경섬유층(RNFL)의 고해상도 산성광간섭단층촬영(SD-OCT)을 기반으로 한 당뇨병성 망막병변 및 녹내상의 조기 진단 기술을 연구하고 있습니다. 특히, 고도근시와 시신경두부 크기의 영향을 분석하며, 환자의 생체정보에 맞춘 정밀 진단 모델 개발에 주력하고 있습니다. 또한, 딥러닝 기반 분석 시스템을 활용해 임상적 기준을 초월한 정확도 높은 병변 탐지 성능을 확보하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15There were no significant differences between the AUROCs for Cirrus GCIPL, RNFL, and ONH parameters, indicating that these maps have similar diagnostic potentials for glaucoma. The minimum GCIPL showed better glaucoma diagnostic performance than the other parameters at comparable specificities. However, other GCIPL parameters showed performances comparable to those of the RNFL parameters.
In cases of high myopia, the glaucoma detection ability of macular GCIPL thickness was high and comparable with that of peripapillary RNFL thickness.
There were no significant differences between the AUROCs for Cirrus and Stratus OCT, indicating that the two devices have similar diagnostic potentials in preperimetric glaucoma. After comparison with their normative databases, Cirrus OCT had generally higher sensitivities; however, this was largely at the cost of lower specificities than Stratus OCT.
To determine the influences of myopia and optic disc size on ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thickness profiles obtained by spectral domain optical coherence tomography (OCT). One hundred and sixty-eight eyes of 168 young myopic subjects were recruited and assigned to one of three groups according to their spherical equivalent (SE) values and optic disc area. All underwent Cirrus HD-OCT imaging. The influences of myopia and optic dis
The combined surgery included a small biometric error that was within the tolerable range in most cases. However, myopic shifts developed in patients with long axial lengths, poor preoperative visual acuity, and the preoperative presence of foveal detachment.
PRéCIS:: A spectral-domain optical coherence tomography (SD-OCT) based deep learning system detected glaucomatous structural change with high sensitivity and specificity. It outperformed the clinical diagnostic parameters in discriminating glaucomatous eyes from healthy eyes. PURPOSE: The purpose of this study was to assess the performance of a deep learning classifier for the detection of glaucomatous change based on SD-OCT. METHODS: Three hundred fifty image sets of ganglion cell-inner plexifo
PURPOSE: To evaluate the diagnostic ability of layer-by-layer segmented macular ganglion cell complex (GCC) using spectral-domain optical coherence tomography (OCT) for detection of glaucoma and to analyze the topographic patterns of the segmented thicknesses in open-angle glaucoma. METHODS: Seventy-seven open-angle glaucoma patients and 59 healthy subjects were enrolled in this cross-sectional study. Spectral-domain OCT with automated segmentation was used to measure the separate thicknesses of
PURPOSE: To evaluate the diagnostic ability of wide-field retinal nerve fiber layer (RNFL) maps with swept-source optical coherence tomography (SS-OCT) for detection of preperimetric (PPG) and early perimetric glaucoma (EG). METHODS: One hundred eighty-four eyes, including 67 healthy eyes, 43 eyes with PPG, and 74 eyes with EG, were analyzed. Patients underwent a comprehensive ocular examination including red-free RNFL photography, visual field testing and wide-field SS-OCT scanning (DRI-OCT-1 A
LC posterior bowing was increased in POAG eyes, and was significantly associated with structural optic nerve head (ONH) changes but not with functional glaucoma severity. Quantitative evaluation of LC curvature can facilitate assessment of glaucomatous ONH change.
Low ocular perfusion pressure (OPP) has been proposed as an important risk factor for glaucoma development and progression, but controversy still exists between studies. Therefore, we conducted a systematic review and meta-analysis to analyze the association between OPP and open-angle glaucoma (OAG). Studies were identified by searching PubMed and EMBASE databases. The pooled absolute and standardised mean difference in OPP between OAG patients and controls were evaluated using the random-effect
The diagnostic ability of macular GCIPL parameters was comparable to that of peripapillary RNFL and ONH parameters in PPG. The inner directional angle of RNFL defects, but not the angular width, affects the diagnostic sensitivity of macular GCIPL parameters.
Objective: We wanted to investigate the prevalence and causative factors of extrahepatic arterial blood supply to hepatocellular carcinoma (HCC) at its initial presentation and during chemoembolization. Materials and Methods: Between February 1998 and April 2000, consecutive 479 patients with newly diagnosed HCC were prospectively enrolled into this study. A total of 1629 sessions of transcatheter arterial chemoembolization (TACE) were performed in these patients (range: 1 15 sessions; mean: 3.4
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