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존아임스 교수

John Ames

성균관대학교 생명과학과 · 생화학·유전·분자생물학

연구실 소개

존아임스 교수의 연구실은 자연계의 유전적 구조와 진화 과정을 장기적인 종합적 관찰을 바탕으로 규명하는 데 초점을 맞추고 있습니다. 특히 플로리다 스컬럽제이의 장기 모니터링 자료를 바탕으로 산란, 이동, 생존, 번식 등 개인 수준의 생태적 행동이 유전적 다양성에 미치는 영향을 정량적으로 분석합니다. 이는 진화 생물학과 유전학의 핵심 문제인 유전자 드리프트, 자연선택, 유전자 이동의 실질적 기여도를 밝혀내는 데 기여합니다. 특히 유전체 분석과 가계도 데이터를 융합한 접근 방식으로, 생태학적 과정과 유전적 결과 간의 직접적 연결을 추론합니다.

장기 생태 관찰유전자 구조 분석가계도 기반 유전학진화 과정 분석플로리다 스컬럽제이

연구 현황

논문 수
89
총 인용 수
2,940
최근 5년 논문
37
주요 분야
생화학·유전·분자생물학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
37총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
211총합
20222023202420252026

주요 논문

15
1
논문|인용수 161·2016
Genomic Consequences of Population Decline in the Endangered Florida Scrub-Jay
Nancy Chen, Elissa J. Cosgrove, Reed Bowman, John W. Fitzpatrick, Andrew G. Clark
SJR Q1Current BiologyOA
GeneticsBiochemistry, Genetics and Molecular Biology
2
논문|인용수 143·2017
Deconstructing isolation-by-distance: The genomic consequences of limited dispersal
Stepfanie M. Aguillon, John W. Fitzpatrick, Reed Bowman, Stephan J. Schoech, Andrew G. Clark, Graham Coop, Nancy Chen
SJR Q1PLoS GeneticsOA

Geographically limited dispersal can shape genetic population structure and result in a correlation between genetic and geographic distance, commonly called isolation-by-distance. Despite the prevalence of isolation-by-distance in nature, to date few studies have empirically demonstrated the processes that generate this pattern, largely because few populations have direct measures of individual dispersal and pedigree information. Intensive, long-term demographic studies and exhaustive genomic su

GeneticsBiochemistry, Genetics and Molecular Biology
3
논문|인용수 116·2018
Allele frequency dynamics in a pedigreed natural population
Nancy Chen, Ivan Jurić, Elissa J. Cosgrove, Reed Bowman, John W. Fitzpatrick, Stephan J. Schoech, Andrew G. Clark, Graham Coop
SJR Q1Proceedings of the National Academy of SciencesOA

A central goal of population genetics is to understand how genetic drift, natural selection, and gene flow shape allele frequencies through time. However, the actual processes underlying these changes—variation in individual survival, reproductive success, and movement—are often difficult to quantify. Fully understanding these processes requires the population pedigree, the set of relationships among all individuals in the population through time. Here, we use extensive pedigree and genomic info

GeneticsBiochemistry, Genetics and Molecular Biology
4
논문|인용수 98·2005
Macroscopic thermoelectric inhomogeneities in (AgSbTe2)x(PbTe)1−x
Nancy Chen, Franck Gascoin, G. Jeffrey Snyder, Eckhard Müller, G. Karpinski, Christian Stiewe
SJR Q1Applied Physics LettersOA

Exceptionally high thermoelectric figure of merit (zT>2), has been reported for (Ag1−ySbTe2)0.05(PbTe)0.95, which may involve the nanoscale microstructure. However, conflicting reports on the same materials claim only zT of 1 or less. Here we show that (Ag1−ySbTe2)0.05(PbTe)0.95 materials are multiphase on the scale of millimeters despite appearing homogeneous by x-ray diffraction and routine electron microscopy. Using a scanning Seebeck microprobe, we find significant variation of Seebec

Materials ChemistryMaterials Science
5
논문|인용수 57·2012
Identification of avian W-linked contigs by short-read sequencing
Nancy Chen, Daniel W. Bellott, David C. Page, Andrew G. Clark
SJR Q2DOAJ (DOAJ: Directory of Open Access Journals)OA

Abstract Background The female-specific W chromosomes and male-specific Y chromosomes have proven difficult to assemble with whole-genome shotgun methods, creating a demand for new approaches to identify sequence contigs specific to these sex chromosomes. Here, we develop and apply a novel method for identifying sequences that are W-specific. Results Using the Illumina Genome Analyzer, we generated sequence reads from a male domestic chicken (ZZ) and mapped them to the existing female (ZW) genom

GeneticsBiochemistry, Genetics and Molecular Biology
6
논문|인용수 45·2014
Using Mendelian Inheritance To Improve High-Throughput SNP Discovery
Nancy Chen, Cristopher V. Van Hout, Srikanth Gottipati, Andrew G. Clark
SJR Q1GeneticsOA

Restriction site-associated DNA sequencing or genotyping-by-sequencing (GBS) approaches allow for rapid and cost-effective discovery and genotyping of thousands of single-nucleotide polymorphisms (SNPs) in multiple individuals. However, rigorous quality control practices are needed to avoid high levels of error and bias with these reduced representation methods. We developed a formal statistical framework for filtering spurious loci, using Mendelian inheritance patterns in nuclear families, that

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
preprint|인용수 43·2018
Allele frequency dynamics in a pedigreed natural population
Nancy Chen, Ivan Jurić, Elissa J. Cosgrove, Reed Bowman, John W. Fitzpatrick, Stephan J. Schoech, Andrew G. Clark, Graham Coop
bioRxiv (Cold Spring Harbor Laboratory)OA

ABSTRACT A central goal of population genetics is to understand how genetic drift, natural selection, and gene flow shape allele frequencies through time. However, the actual processes underlying these changes - variation in individual survival, reproductive success, and movement - are often difficult to quantify. Fully understanding these processes requires the population pedigree, the set of relationships among all individuals in the population through time. Here, we use extensive pedigree and

GeneticsBiochemistry, Genetics and Molecular Biology
8
letter|인용수 35·2019
Conservation: Bye-Bye to the Hihi?
Nancy Chen
SJR Q1Current BiologyOA
GeneticsBiochemistry, Genetics and Molecular Biology
9
논문|인용수 21·2022
Nature, Data, and Power: How Hegemonies Shaped This Special Section
Ambika Kamath, Beans Velocci, Ashton Wesner, Nancy Chen, Vince A. Formica, Banu Subramaniam, María Rebolleda‐Gómez
SJR Q1The American Naturalist

AbstractSystems of oppression-racism, colonialism, misogyny, cissexism, ableism, heteronormativity, and more-have long shaped the content and practice of science. But opportunities to reckon with these influences are rarely found within academic science, even though such critiques are well developed in the social sciences and humanities. In this special section, we attempt to bring cross-disciplinary conversations among ecology, evolution, behavior, and genetics on the one hand and critical pers

GeneticsBiochemistry, Genetics and Molecular Biology
10
preprint|인용수 15·2016
Deconstructing isolation-by-distance: the genomic consequences of limited dispersal
Stepfanie M. Aguillon, John W. Fitzpatrick, Reed Bowman, Stephan J. Schoech, Andrew G. Clark, Graham Coop, Nancy Chen
bioRxiv (Cold Spring Harbor Laboratory)OA

Abstract Geographically limited dispersal can shape genetic population structure and result in a correlation between genetic and geographic distance, commonly called isolation-bydistance. Despite the prevalence of isolation-by-distance in nature, to date few studies have empirically demonstrated the processes that generate this pattern, largely because few populations have direct measures of individual dispersal and pedigree information. Intensive, long-term demographic studies and exhaustive ge

GeneticsBiochemistry, Genetics and Molecular Biology
11
논문|인용수 7·2024
Density dependence maintains long‐term stability despite increased isolation and inbreeding in the Florida Scrub‐Jay
Jeremy Summers, Elissa J. Cosgrove, Reed Bowman, John W. Fitzpatrick, Nancy Chen
SJR Q1Ecology LettersOA

Isolation caused by anthropogenic habitat fragmentation can destabilize populations. Populations relying on the inflow of immigrants can face reduced fitness due to inbreeding depression as fewer new individuals arrive. Empirical studies of the demographic consequences of isolation are critical to understand how populations persist through changing conditions. We used a 34-year demographic and environmental dataset from a population of cooperatively breeding Florida Scrub-Jays (Aphelocoma coerul

Nature and Landscape ConservationEnvironmental Science
12
letter|인용수 5·2020
A gene for color differences between sexes
Nancy Chen
SJR Q1Science

Sex differences in plumage color in hybrid canaries are controlled by a single enzyme

Ecology, Evolution, Behavior and SystematicsAgricultural and Biological Sciences
13
논문|인용수 4·2024
Allele frequency dynamics under sex-biased demography and sex-specific inheritance in a pedigreed jay population
Rose M. H. Driscoll, Felix E.G. Beaudry, Elissa J. Cosgrove, Reed Bowman, John W. Fitzpatrick, Stephan J. Schoech, Nancy Chen
SJR Q1GeneticsOA

Sex-biased demography, including sex-biased survival or migration, can alter allele frequency changes across the genome. In particular, we can expect different patterns of genetic variation on autosomes and sex chromosomes due to sex-specific differences in life histories, as well as differences in effective population size, transmission modes, and the strength and mode of selection. Here, we demonstrate the role that sex differences in life history played in shaping short-term evolutionary dyna

GeneticsBiochemistry, Genetics and Molecular Biology
14
preprint|인용수 2·2025
Context-Dependent Fitness Outcomes of Helping in the Cooperatively-Breeding Florida Scrub-Jay ( Aphelocoma coerulescens )
Jeremy Summers, Bailey S.C.L. Jones, Elissa J. Cosgrove, Tori D. Bakley, Sahas Barve, Reed Bowman, John W. Fitzpatrick, Nancy Chen
bioRxiv (Cold Spring Harbor Laboratory)OA

Abstract Cooperatively breeding species frequently live in family groups of related individuals, with helpers delaying their own reproduction and participating in alloparental care, predator vigilance, and territory defense. It remains challenging to disentangle the roles of the indirect fitness benefits of helping kin and the potential direct fitness benefits helpers receive in the evolution of cooperative breeding. While many studies test for associations between helper relatedness and helping

Ecology, Evolution, Behavior and SystematicsAgricultural and Biological Sciences
15
논문|인용수 1·2024
Gender Differences in the Association Between Subjective and Objective Cognitive Decline in a Diverse Cohort: LifeAfter90 Study
Nancy Chen, María M. Corrada, Paola Gilsanz, Sarah Tomaszewski Farias, Kristen M. George, Alexander Ivan B. Posis, Claire C. Meunier, Yi Lor, Rachel A. Whitmer
SJR Q1Alzheimer s & DementiaOA

Abstract Background Few studies have investigated the relationship between subjective cognitive concerns and objective cognitive decline in the oldest‐old or examined gender differences. We evaluated this association and stratification by gender in a diverse cohort of adults ages 90+. Methods LifeAfter90 is an ongoing cohort of adults ages 90+. Verbal episodic memory (VEM) and executive function (EF) were assessed every 6‐months since 2018 using the Spanish and English Neuropsychological Assessm

Psychiatry and Mental healthMedicine

대표 연구 분야

GeneticsMolecular BiologyNature and Landscape ConservationOceanographyEcological ModelingEcology, Evolution, Behavior and Systematics

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