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한종철 교수

Jong Chul Han

성균관대학교 의학과 · 의학

연구실 소개

한종철 교수의 연구실은 주로 망막신경섬유층과 시신경두부의 구조적 변화를 고해상도 산란광학단층촬영(EDI-OCT)을 활용해 분석하며, 특히 근시성 및 정상내압성 녹내망의 병태생리학적 기전을 규명하는 데 초점을 맞추고 있습니다. 축구공처럼 기울어진 시신경두부나 라amina cribrosa의 구조적 손상 등 시신경두부의 기형적 특성과 시신경 손상의 연관성을 다루며, 신경세포 보존과 조기 진단을 위한 인공지능 기반 진단 알고리즘 개발도 함께 진행하고 있습니다. 특히 내과적 요법과 수술적 치료의 장기적 결과 비교를 통한 치료 전략 최적화에도 기여하고 있습니다.

근시성 녹내망시신경두부 구조EDI-OCT정상내압성 녹내망인공지능 진단

연구 현황

논문 수
155
총 인용 수
1,554
최근 5년 논문
39
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
39총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
81총합
20222023202420252026

주요 논문

15
1
논문|인용수 53·2016
Visual Field Progression Pattern Associated With Optic Disc Tilt Morphology in Myopic Open-Angle Glaucoma
Jong Chul Han, Eun Jung Lee, Seung Hoon Kim, Changwon Kee
SJR Q1American Journal of Ophthalmology
OphthalmologyMedicine
2
논문|인용수 53·2016
The Characteristics of Lamina Cribrosa Defects in Myopic Eyes With and Without Open-Angle Glaucoma
Jong Chul Han, Seok Ho Cho, Dae Yong Sohn, Changwon Kee
SJR Q1Investigative Ophthalmology & Visual ScienceOA

PURPOSE: We investigated the lamina cribrosa (LC) structural characteristics of myopic eyes with and without open-angle glaucoma (OAG) using enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT). METHODS: Defects in the LC in myopic eyes with and without OAG and normal eyes without myopia were evaluated using EDI SD-OCT. Among the two types of LC defects, disinsertion type and hole type, the associations among disinsertion type LC defects, myopia-related parameters of

OphthalmologyMedicine
3
논문|인용수 44·2020
Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography
Ko Eun Kim, Joon Mo Kim, Ji Eun Song, Changwon Kee, Jong Chul Han, Seung Hyup Hyun
SJR Q1Journal of Clinical MedicineOA

This study aimed to develop and validate a deep learning system for diagnosing glaucoma using optical coherence tomography (OCT). A training set of 1822 eyes (332 control, 1490 glaucoma) with 7288 OCT images, an internal validation set of 425 eyes (104 control, 321 glaucoma) with 1700 images, and an external validation set of 355 eyes (108 control, 247 glaucoma) with 1420 images were included. Deviation and thickness maps of retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform laye

Radiology, Nuclear Medicine and ImagingMedicine
4
논문|인용수 36·2019
Clinical Course and Risk Factors for Visual Field Progression in Normal-Tension Glaucoma With Myopia Without Glaucoma Medications
Jong Chul Han, Sun Han, Do Young Park, Eun Jung Lee, Changwon Kee
SJR Q1American Journal of Ophthalmology
OphthalmologyMedicine
5
논문|인용수 36·2016
The Effect of Diurnal Fluctuation in Intraocular Pressure on the Evaluation of Risk Factors of Progression in Normal Tension Glaucoma
Seung Hoon Kim, Eun Jung Lee, Jong Chul Han, Sae Woon Sohn, Taekkwan Rhee, Changwon Kee
SJR Q1PLoS ONEOA

Although having the same IOP-related factors, if diurnal fluctuation is included, different results may be found on the relationship between IOP-related factors and NTG progression. Based on our results, diurnal fluctuation in IOP should be considered when IOP-related factors are studied in the future.

OphthalmologyMedicine
6
논문|인용수 35·2017
The Characteristics of Deep Optic Nerve Head Morphology in Myopic Normal Tension Glaucoma
Jong Chul Han, Eun Jung Lee, Si Bum Kim, Changwon Kee
SJR Q1Investigative Ophthalmology & Visual ScienceOA

Purpose: To investigate the relationship between axial length (AL) and deep optic nerve head (ONH) structure and to evaluate the characteristics of deep ONH structures in myopic normal tension glaucoma (NTG). Methods: The following parameters were assessed using spectral-domain optical coherence tomography (SD-OCT): externally oblique border tissue (EOBT) length, ONH tilt angle, optic canal (OC) obliqueness, and β-zone peripapillary atrophy (PPA). In addition, the angular location of the maximal

OphthalmologyMedicine
7
논문|인용수 32·2014
Single-shot dual-energy x-ray imaging with a flat-panel sandwich detector for preclinical imaging
Jong Chul Han, Ho Kyung Kim, Dong Woon Kim, Seungman Yun, Hanbean Youn, Soohwa Kam, Jesse Tanguay, Ian A. Cunningham
SJR Q2Current Applied Physics
Biomedical EngineeringEngineering
8
논문|인용수 26·2019
Border Tissue Morphology Is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma
Jong Chul Han, Jae Hwan Choi, Do Young Park, Eun Jung Lee, Changwon Kee
SJR Q1American Journal of Ophthalmology
OphthalmologyMedicine
9
논문|인용수 21·2015
Long-term outcomes of argon laser photocoagulation in small size cyclodialysis cleft
Jong Chul Han, Young Kyo Kwun, Seok Ho Cho, Changwon Kee
SJR Q2BMC OphthalmologyOA

BACKGROUND: To evaluate the long-term outcomes of Argon laser photocoagulation compared to surgical direct cyclopexy in small-size cyclodialysis cleft patients. METHODS: This is a retrospective study. Small-size cyclodialysis cleft patients who underwent Argon laser photocoagulation and surgical direct cyclopexy were reviewed. The mean follow-up period were 82.4 (range, 61 - 145) months and 99.9 (range, 62 - 184) months in both groups. The comparison of best corrected visual acuity (BCVA), intra

OphthalmologyMedicine
10
논문|인용수 15·2015
Evaluation of lamina cribrosa thickness and depth in ocular hypertension
Jong Chul Han, Daye Choi, Young Kyo Kwun, Wool Suh, Changwon Kee
SJR Q2Japanese Journal of Ophthalmology
Radiology, Nuclear Medicine and ImagingMedicine
11
논문|인용수 14·2016
Optic Disc Characteristics and Visual Field Progression in Normal Tension Glaucoma Patients With Tilted Optic Discs
Youngkyo Kwun, Gyule Han, Yoon‐Jung Choy, Jong Chul Han, Changwon Kee
SJR Q1Journal of Glaucoma

PURPOSE OF THE STUDY: The purpose of the study was to evaluate the optic disc characteristics associated with visual field (VF) progression in normal tension glaucoma (NTG) eyes with tilted optic discs. METHODS: Sixty-six eyes of 66 NTG patients with tilted optic disc were included in this cross-sectional study, who were examined by at least 5 Humphrey 30-2 VFs. Glaucomatous VF progression was evaluated using pointwise linear regression. Optic nerve heads were scanned with enhanced-depth imaging

OphthalmologyMedicine
12
논문|인용수 13·2024
Differential protein expression and metabolite profiling in glaucoma: Insights from a multi‐omics analysis
Jeong-Hun Mok, Do Young Park, Jong Chul Han
SJR Q1BioFactorsOA

Various substances within the aqueous humor (AH) can directly or indirectly impact intraocular tissues associated with intraocular pressure (IOP), a critical factor in glaucoma development. This study aims to investigate individual changes in these AH substances and the interactions among altered components through a multi-omics approach. LC/MS analysis was conducted on AH samples from patients with exfoliation syndrome (XFS, n = 5), exfoliation glaucoma (XFG, n = 4), primary open-angle glaucoma

OphthalmologyMedicine
13
논문|인용수 12·2015
The Different Characteristics of Cirrus Optical Coherence Tomography between Superior Segmental Optic Hypoplasia and Normal Tension Glaucoma with Superior Retinal Nerve Fiber Defect
Jong Chul Han, Da Ye Choi, Changwon Kee
SJR Q2Journal of OphthalmologyOA

Purpose. To evaluate the different characteristics in superior segmental optic hypoplasia (SSOH) and normal tension glaucoma (NTG) with superior retinal nerve fiber layer (RNFL) defect (NTG-SRD) compared to normal control using cirrus optical coherence tomography (OCT). Methods. SSOH eyes and NTG-SRD eyes were reviewed. The peripapillary RNFL (pRNFL) and ganglion cell inner plexiform layer (GCIPL) of the two groups were compared to age-matched normal controls using cirrus OCT. Results. Included

OphthalmologyMedicine
14
논문|인용수 12·2016
Membrane-tube-type glaucoma shunt device for refractory glaucoma surgery
Jong Chul Han, Young Hoon Hwang, Byung Heon Ahn
SJR Q1Graefe s Archive for Clinical and Experimental Ophthalmology
OphthalmologyMedicine
15
논문|인용수 11·2009
Feasibility study of CMOS detectors for mammography
Jong Chul Han, Seungman Yun, Chang Hwy Lim, Tae‐Woo Kim, Ho Kyung Kim
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

We investigated the potential use of CMOS (complementary metal-oxide-semiconductor) imaging detectors with a pixel pitch of 48 μm for mammography. Fundamental imaging characteristics were evaluated in terms of modulation-transfer function (MTF), noise-power spectrum (NPS), and detective quantum efficiency (DQE). The magnitudes of various image noise sources, such as optical photons, direct x rays unattenuated and scattered x rays from the scintillator, and additive electronic noise, were meas

Pulmonary and Respiratory MedicineMedicine

대표 연구 분야

OphthalmologyRadiology, Nuclear Medicine and ImagingBiomedical EngineeringNuclear and High Energy PhysicsPulmonary and Respiratory MedicinePathology and Forensic Medicine

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