한종인 교수

Recently, we encounter several articles regarding urinary trypsin inhibitor (UTI) published nationally When we take a glance at these articles, it feels like UTI acts as a miraculous medicine on patients under general anesthesia because of its protection effect against surgical stress. Yet, even after the first report on antitryptic action of urine by Bauer and Reich III in 1909 [3]; the start of use of the term UTI by Astrup and Sterndorff in 1955 [4]; and numerous animal experiments and clinic

Alzheimer’s disease (AD), one of the most prevalent neurodegenerative diseases is associated with pathological autophagy-lysosomal pathway dysfunction. Dexmedetomidine (Dex) has been suggested as an adjuvant to general anesthesia with advantages in reducing the incidence of postoperative cognitive dysfunction in Dex-treated patients with AD and older individuals. Several studies reported that Dex improved memory; however, evidence on the effects of Dex on neuronal autophagy dysfunction in the AD

Since Bohrer et al. [1] reported in 1990 that administering fentanyl through a central venous catheter induces the cough reflex, it has become well-known that remifentanil and fentanyl used for inducing general anesthesia cause a cough in various types of clinical situations. This has led to many clinical studies [2-4] thus far, and the research paper of Yoo et al. [5] is also included in this group. The proposed mechanisms through which opioids induce a cough are as follows: (1) pulmonary ch

Background: This study compared the modified BronchoCath double-lumen endotracheal tube (DLT) with the Univent bronchial blocker and Arndt's wire-guided endobronchial blocker (WEB) to determine whether there were objective advantages of one over the other during anesthesia with one lung ventilation.

No abstract available

We wanted to determine an adequate combination of target effect-site concentrations of remifentanil and propofol during anesthetic induction with target controlled infusion (TCI). We also determined whether increasing remifentanil concentrations might reduce propofol consumption at loss of consciousness (LOC).

We wanted to determine an adequate combination of target effect-site concentrations of remifentanil and propofol during anesthetic induction with target controlled infusion (TCI).We also determined whether increasing remifentanil concentrations might reduce propofol consumption at loss of consciousness (LOC). Methods: Sixty ASA 1 or 2 patients were randomly allocated according to the target effect-site concentration of remifentanil and propofol (R7P3: remifentanil 7 ng/ml + propofol 3μg/ml, R5

Propofol 1,2) (2.9 mg/kg) (2.5 mg/kg) Marsh 3) 50% 25% . opioid propofol . (TCI, target controlled infusion) (TIVA, total intravenous anesthesia) opioid propofol TCI . propofol TCI Diprifusor TM (Master TCI: Fresenius Vial S.A., France) (pharmacokinetic model) . 4) Stelpump TCI