박종필 교수
Jong Pil Park
연세대학교 법의학과 · 의학
연구실 소개
박종필 교수의 연구실은 의료 생물학적 마커와 진단 기술 개발을 중심으로 활동하고 있습니다. 특히 트로포닌 I와 같은 심장 손상 관련 단백질을 정밀하게 탐지할 수 있는 펩타이드 기반 진단 플랫폼을 개발하며, 생체막대물질의 특이적 인식 기술을 연구하고 있습니다. 또한, 임상 영상 및 생체 신호 분석을 통해 혈관성 질환의 조기 진단 및 예후 평가에 기여할 수 있는 기술적 접근도 함께 진행하고 있습니다. 최근에는 의료 영상 데이터 기반의 운동 패턴 분석 및 구조적 분석 기법을 활용한 의료 정보 처리 기술 개발에도 진전을 보이고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Troponin I is a specific and sensitive clinical biomarker for myocardial injury. In this study we have used polyvalent phage display to isolate unique linear peptide motifs which recognize both the human and rat homologs of troponin I. The peptide specific for human troponin I has a sequence of FYSHSFHENWPS and the peptide specific for the rat troponin I has a sequence of FHSSWPVNGSTI. Enzyme-linked immunosorbent assays (ELISAs) were used to evaluate the binding interactions, and the two phage-d
Social media marketing plays an increasingly important role in the hotel and tourism industry. This study examines how social networking services, microblogs and social commerce sites are used in the field of tourism in a case study of KAL (Korean Airline) Tour, one of the leading travel agencies based in Korea. This study shows that companies make a substantial amount of profits from their investments in social media marketing activities. KAL Tour uses a variety of social media for effective so
Among the biomarkers tested in this study, the MMP-9 level was significantly higher in patients with ruptured plaque. However, measurement of several biomarkers, including MMP-9, was incapable of predicting the presence of VH-TCFA.
The autopsy rate in Korea is lower compared to that of the advanced countries. These findings implicate the need for nationwide policy to promote both clinical and legal autopsy, which remain crucial parts of medical science and public health.
Giant multilocular prostatic cystadenoma (GMPC) is a rare benign tumor involving the prostate gland. Microscopically, it masquerades phyllodes tumor or transitional zone hyperplasia. We report one case of GMPC arising from the prostate central zone (CZ), presenting with long-standing aspermia associated with seminal vesicle fibrous obliteration.
Abstract We present a new approach to motion rearrangement that preserves the syntactic structures of an input motion automatically by learning a context‐free grammar from the motion data. For grammatical analysis, we reduce an input motion into a string of terminal symbols by segmenting the motion into a series of subsequences, and then associating a group of similar subsequences with the same symbol. To obtain the most repetitive and precise set of terminals, we search for an optimial segmenta
Background: The autopsy is the medical examination of a deceased person that mainly provides information on the cause and manner of death. Two types are conducted in Korea: clinical and legal, depending on its purpose. Despite this procedure's importance, autopsy rates have been decreasing worldwide. The aim of this study was to determine the nationwide autopsy rate in Korea and compare it with that in other countries. Methods: We collected data of autopsies performed between 2001 and 2015 by se
This study investigates the relationships among the influence of the largest shareholder, the entry mode of foreign direct investment companies in Korea, and subsidiary divestitures to demonstrate how the government's FDI policies can work as a moderator. Using data from 468 foreign manufacturing firms that set up plants in Korea through FDI between 2008 and 2011, a survival analysis was performed using the Cox proportional hazards model. The statistical results suggest that the possibility of f
Glomus tumor is a tumor arising from glomus body, a nodular form of arteriolovenular anastomosis that functions to regulate blood flow according to temperature. Gastrointestinal glomus tumors are rare and most frequently occur in the stomach as a subepithelial tumor. A 46-year-old woman presented with an incidental finding of a subepithelial tumor in the stomach. Endoscopic ultrasonography (EUS) showed a 1.4chi1 cm sized well circumscribed heterogeneous hypoechoic tumor with a few tubular struct
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