박종선 교수

Our findings indicate that depression and anxiety are relatively common in patients with IPF. Although no significant differences were noted with regard to survival rate and hospitalization, the present study suggests that depression and anxiety significantly influence quality of life in patients with IPF.

Therapeutic drug monitoring in tuberculosis remains controversial. We evaluated the relationship between antituberculosis drug levels in blood and clinical outcome. Serum concentrations of first-line antituberculosis drugs were measured in tuberculosis patients between March 2006 and April 2013. Venous blood was drawn 2 h after drug ingestion and was analyzed using high-performance liquid chromatography-tandem mass spectrometry. We retrospectively reviewed the data and determined the association

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown causes. Three proteins (mammalian target of rapamycin, mTOR; zinc finger E-box-binding homeobox 1, ZEB1; Rho-associated, coiled-coil containing protein kinase 1, ROCK1) may be related to pulmonary fibrosis. However, they have not been assessed in human pulmonary fibrosis. We assessed the clinical significance of mTOR, ZEB1, and ROCK1 expression in human pulmonary fibrosis of usual interstitial pneumonia (UIP) patt

BACKGROUND: Carcinoma of unknown primary tumors (CUP) is present in 0.5%-9% of all patients with malignant neoplasms; only 20%-27% of primary sites are identified before the patients die. Currently, 18F-fluorodeoxy-glucose positron-emission tomography (18F-FDG PET) or PET combined with computed tomography (PET/CT) is widely used for the diagnosis of CUP. However, the diagnostic yield of the primary site varies. The aim of this study was to determine whether PET or PET/CT has additional advantage

BACKGROUND: The effects of corticosteroid-based therapy in patients with idiopathic nonspecific interstitial pneumonia (iNSIP), and factors affecting treatment outcome, are not fully understood. We aimed to investigate the long-term treatment response and factors affecting the treatment outcome in iNSIP patients from a multi-center study in Korea. METHODS: The Korean interstitial lung disease (ILD) Study Group surveyed ILD patients from 2003 to 2007. Patients were divided into two groups to comp

이 연구의 목적은 일터학습에 영향을 미치는 조직특성 변인을 다룬 문헌들을 고찰함으로서, 일터학습 조직특성 변인과 각 변인들에 대한 실증연구들을 종합하고 추후 일터학습 관련 조직특성 변인 연구를 위한 시사점을 도출하는 데 있었다. 이와 같은 목적을 달성하기 위하여 1990년부터 2010년까지의 일터학습 조직특성 변인 관련 연구 29편을 고찰하였으며, 참여와 권한위임, 의사소통, 외부환경과의 접촉, 학습기회 제공, 개방성, 혁신과 위험감수, 능력주의와 보상, 비전 및 정보공유, 상사의 지원, 동료관계 등 10개의 주요한 조직특성 변인을 구명하였다. 각각의 조직특성 변인이 일터학습과 갖는 관계를 세 가지 분류로 나누어 본 결과, 참여와 권한위임, 능력주의와 보상, 상사의 지원은 일터학습과 유의미한 관계를 갖는 것으로, 의사소통, 외부환경과의 접촉, 혁신과 위험감수는 엇갈리는 결과가 존재하는 것으로, 학습기회 제공, 개방성, 비전 및 정보공유, 동료관계는 실증 연구가 거의 존재하지 않는 것

BACKGROUND: Acute fibrinous and organizing pneumonia (AFOP) is a rare interstitial pneumonia characterized by intra-alveolar fibrin deposition and organizing pneumonia. The clinical manifestations and long-term prognosis of AFOP are unclear. Our objective was to investigate the clinical features and prognosis of AFOP. METHODS: We identified patients diagnosed with AFOP by surgical lung biopsy between January 2011 and May 2018 at Seoul National University Bundang Hospital. We retrospectively revi