박종철 교수
Jong‐Chul Park
연세대학교 의학공학과 · 의학
연구실 소개
박종철 교수의 연구실은 생체재료 및 나노소재를 기반으로 한 조직공학과 재생의료 분야에서 활발한 연구를 수행하고 있습니다. 특히 히알루론산 유사 구조를 가진 RGD/PLGA 나노섬유 기반 매트릭스와 그래핀을 활용한 신경세포 부착 및 신경돌기 성장 촉진 기술, 그리고 폴리우레탄 표면에 타입 I 아텔로콜라겐을 접합시키는 그라프팅 기술을 통해 인체 조직 재생을 위한 고도화된 생체재료를 개발하고 있습니다. 또한 EGCG의 세포 노화 억제 효과와 해충 미생물 제거를 위한 저전류 전기처리 기술 등 다양한 생물의학적 응용을 탐색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15In conclusion, these findings propose that the combination of RGD/PLGA nanofiber matrices and GO can be used as a promising strategy for skeletal tissue engineering and regeneration.
Neural cell adhesion and neurite outgrowth were examined on graphene-based biomimetic substrates. The biocompatibility of carbon nanomaterials such as graphene and carbon nanotubes (CNTs), that is, single-walled and multiwalled CNTs, against pheochromocytoma-derived PC-12 neural cells was also evaluated by quantifying metabolic activity (with WST-8 assay), intracellular oxidative stress (with ROS assay), and membrane integrity (with LDH assay). Graphene films were grown by using chemical vapor d
The influence of mood states on the propensity to use heuristics as expressed in stereotypes was examined using signal detection statistics. Participants experienced happy, neutral, or sad moods and "remembered" whether names connoting race (African American, European American) belonged to social categories (criminal, politician, basketball player). Positive mood increased reliance on heuristics, indexed by higher false identification of members of stereotyped groups. Positive mood lowered sensi
Seawater used in mariculture has been suspected of being a potential source of infection. In this study, the lethal effects of low-amperage electric treatment on microorganisms were examined in natural seawater and in seawater inoculated with Vibrio parahaemolyticus. In both cases, bacteria including V. parahaemolyticus in seawater were completely eliminated in 100 ms by a 0.5-A, 12-V direct current. Electron microscopic investigation of the electrically treated bacteria revealed substantial str
An approach is presented for the graft copolymerization of type I atelocollagen onto the surface of polyurethane (PU) films treated with ozone. Through inducing oxidization to modify PU surface by ozone, peroxide groups are easily generated on the surface. Those peroxides are broken by redox-polymerization, and provide active species which initiate graft polymerization by reacting with amines in the collagen molecules. The ozone oxidation time and voltage could readily control the amount of pero
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