박종호 교수

p53 plays a pivotal role in tumour suppression under stresses, such as DNA damage. ISG15 has been implicated in the control of tumorigenesis. Intriguingly, the expression of ISG15, UBE1L and UBCH8 is induced by DNA-damaging agents, such as ultraviolet and doxorubicin, which are known to induce p53. Here, we show that the genes encoding ISG15, UBE1L, UBCH8 and EFP, have the p53-responsive elements and their expression is induced in a p53-dependent fashion under DNA damage conditions. Furthermore,

The functional and evolutionary significance of DNA methylation in insect genomes remains to be resolved. Nasonia is well situated for comparative analyses of DNA methylation and genome evolution, since the genomes of a moderately distant outgroup species as well as closely related sibling species are available. Using direct sequencing of bisulfite-converted DNA, we uncovered a substantial level of DNA methylation in 17 of 18 Nasonia vitripennis genes and a strong correlation between methylation

Abstract We study Faraday rotation in the jet of M87 inside the Bondi radius using eight Very Long Baseline Array data sets, one at 8 GHz, four at 5 GHz, and three at 2 GHz. We obtain Faraday rotation measures (RMs) measured across the bandwidth of each data set. We find that the magnitude of RM systematically decreases with increasing distance from 5000 to 200,000 Schwarzschild radii. The data, showing predominantly negative RM signs without significant difference of the RMs on the northern and

This document describes the SEED encryption algorithm, which has been adopted by most of the security systems in the Republic of Korea. Included are a description of the cipher and the key scheduling algorithm (Section 2), the S-boxes (Appendix A), and a set of test vectors (Appendix B).

Abstract PKS 1510–089 is a bright and active γ -ray source that showed strong and complex γ -ray flares in mid-2015 during which the Major Atmospheric Gamma Imaging Cerenkov telescopes detected variable very high energy (photon energies >100 GeV) emission. We present long-term multifrequency radio, optical, and γ -ray light curves of PKS 1510–089 from 2013 to 2018, and results of an analysis of the jet kinematics and linear polarization using 43 GHz Very Long Baseline Array data observed betw

Abstract We report the first observation of the nearby giant radio galaxy NGC 315 using a global very long baseline interferometry (VLBI) array consisting of 22 radio antennas located across five continents, including high-sensitivity stations, at 22 GHz. Utilizing the extensive u v -coverage provided by the array, coupled with the application of a recently developed superresolution imaging technique based on the regularized maximum-likelihood method, we were able to transversely resolve the NGC

The linear polarization images of the jet in the giant elliptical galaxy M87 have previously been observed with Very Long Baseline Array at 7 mm. They exhibit a complex polarization structure surrounding the optically thick and compact subparsec-scale core. However, given the low level of linear polarization in the core, it is required to verify that this complex structure does not originate from residual instrumental polarization signals in the data. We have performed a new analysis of the same

Previous work revealed that booming sound quality is related to loudness and sharpness and that the booming index is developed by using the loudness and sharpness for a signal within the whole frequency range between 20 Hz and 20 kHz. In the present paper, the booming sound quality was found to be effectively related to the loudness at frequencies below 200 Hz; thus the booming index is updated by using the loudness of the signal filtered by the low pass filter at frequencies. The relationship b

Highly collimated relativistic jets are a defining feature of certain active galactic nuclei (AGN), yet their formation mechanism remains elusive. Previous observations and theoretical models have proposed that the ambient medium surrounding the jets could exert pressure, playing a crucial role in shaping the jets. However, a direct observational confirmation of such a medium has been lacking. In this study, we present very long baseline interferometric (VLBI) observations of 3C 84 (NGC 1275), l

The magnetic field is believed to play a critical role in the bulk acceleration and propagation of jets produced in active galactic nuclei (AGN). Polarization observations of AGN jets provide valuable information about their magnetic fields. As a result of radiative transfer, jet structure, and stratification, among other factors, it is not always straightforward to determine the magnetic field structures from observed polarization. We review these effects and their impact on polarization emissi