김종옥 교수

There is lots of evidence to support the critical involvement of mTOR signaling in the carcinogenesis of hepatocellular carcinoma (HCC). However, it has not been determined how the roles of individual mTORC1 and mTORC2 inhibitors played in the HCC therapeutics. We thus compared the effects of everolimus, Ku0063794, and a combination of the two therapies on HCC cells, using various in vitro studies (HepG2, Hep3B, and Huh7 cells), ex vivo culturing of HCC tissues obtained from patients, and the in

It is expected that a number of heterogeneous radio access technologies will be available simultaneously at a single wireless terminal in next generation wireless networks. This paper addresses the challenge of link aggregation in a wireless terminal with multi-radio devices. A major issue in multi-path transmission is how to reduce the additional reordering delay at the receiver, which is mainly caused by the difference between link delays. This is particularly critical in wireless environments

One of the promising solutions to combat wireless channel fluctuations in IEEE 802.11 networks is to appropriately exploit multi-rate capability of the physical layer. The mechanism to adaptively select actual transmission rates based on channel condition is generally referred to as RA (rate adaptation). Recently, T-RA (throughput-based rate adaptation) has been proposed to maximize system capacity. On the other hand, for multimedia traffic, E-RA (error-based rate adaptation) has been proposed,

It is expected that multiple radio access technologies coexist within a single terminal. In those networks, we focus on the problem of how to distribute IP traffic into multiple underlying links in order to enhance the overall aggregated throughput. As an effective aggregation mechanism, traffic is equivalently assigned to each link, in proportion to its available capacity. To this end, the capacity of each link is commonly measured for easy comparison between radio links, and then, the relative

For multi-access networks with heterogeneous radio access techniques, the challenges include the problem of how to optimally distribute network traffics into each radio link in order to enhance the aggregated link capacity. As an effective load balance mechanism, traffics may be equivalently assigned to each RA, in proportion to its available capacity. To this end, airtime cost is identified as a common resource measure for WiMAX and WiFi links. Due to their different data transmission mechanism

The combination of VoIP and WLAN technologies has created a new attractive service, wireless VoIP, and its interest has been increasingly growing in a variety of environments such as offices and public areas. However, mixing voice with data traffic introduces QoS issues because 802.11 DCF does not provide any QoS mechanism. In this paper, an enhanced version of the legacy DCF is proposed in order to support friendly coexistence of voice and data. Every downlink transmission of data packets in an

Abstract We investigate the challenge of splitting a traffic flow over WiMAX and WiFi links. For traffic load distribution over heterogeneous RATs (Radio Access Technologies), heterogeneous link resources need to be commonly measured and fairly compared. To this end, an airtime cost model is considered as a common resource measure. The model can be used to estimate channel time consumed for a successful packet transmission. As a traffic split mechanism, an airtime‐balance method is proposed. Usi

본 연구는 1966년 TBC 동화부의 황금박쥐로 시작된 한국 하청애니메이션의 역사를 1980년대 시기까지 분석하여, 한국애니메이션에서 30년 넘게 진행되어 온 하청애니메이션의 역사를 재조명하였다. 이를 위해 하청애니메이션 제작사 제작현황 산업의 규모 등 하청애니메이션 개괄적인 상황을 통해 당시 OEM산업의 실태를 점검하였고, 애니메이션이 하청제작산업으로 고착화된 배경을 시대상황과 연계하여 분석하였다. 또한 이를 기반으로 하청애니메이션산업이 발생시킨 문제점과 한계 그리고 이를 극복하고 창작애니메이션을 활성화하기 위한 새로운 모색에 대한 분석을 통해 애니메이션 역사 연구의 지평을 넓혀보고자 하였다. 1970년대는 중화학공업 육성과 수출주도형 경제성장이 국가적 목표였던 시기였다. 70년대 후반부터 애니메이션도 해외애니메이션 하청 수주를 통해 수출 주력산업으로 주목받았다. 하청 해니메이션 제작의 확대는 당시 대중문화에 대한 국가의 정책과 칼라TV보급, 비디오 제작 시장 활성화 등의 매체 변

Purpose: A CXCR4/stroma derived factor-1α(SDF-1α , CXCL12) interaction is involved in many metastatic cancer mechanisms, including breast cancer. The primary objectives of this study were to investigate the correlation between CXCR4 and axillary lymph node metastasis and to clarify the interaction between CXCR4 in primary tumor cells and SDF-1αin metastatic lymph nodes. An analysis of the correlation between CXCR4, SDF-1αand clinicopathologic features was also performed. Methods: Representative

In next generation wireless networks, a variety of heterogeneous radio access technologies are expected to be available simultaneously within a single wireless terminal. This paper addresses the challenge of link aggregation in multi-access networks, where a key issue is how to optimally aggregate bandwidth offered by the individual radio link. Effective link throughput model is employed as a common resource measure for heterogeneous links. Based on the model, we present a packet allocation tech

In IEEE 802.11 DCF, performance unfairness inevitably occurs between downlink (AP-to-station) and uplink (station-to-AP) directions. The asymmetry of the DCF operation degrades downlink traffic severely. Therefore, it is important to enhance downlink QoS by alleviating link congestion. In this paper, we propose a novel medium access control scheme, BDCF (Burst DCF), to enhance the legacy DCF. It is designed to provide a level of QoS differentiation with downlink traffic, and can improve downlink