김준영 교수
Joon-young Kim
성균관대학교 의학과 · 의학
연구실 소개
김준영 교수의 연구실은 전이금속 질화물의 합성 및 구조 설계를 통해 초음속기의 고성능 전극 소재를 개발하고 있으며, 특히 에너지 저장 장치의 상용화 기준을 충족시키기 위한 전기화학적 설계 전략에 초점을 맞추고 있습니다. 또한 동물 모델을 활용한 정밀 영상 분석 기법 개발과 함께, 생물학적 분자 간의 상호작용 메커니즘을 규명하는 분야에서도 활발한 연구를 진행하고 있습니다. 최근에는 동물의 눈 건강 진단을 위한 딥러닝 기반 영상 진단 기술 개발을 통해 수의학 분야의 정밀의료 기반을 마련하고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15This review summarizes recent advances in synthesis strategies, structural engineering, and unique properties of transition metal nitrides, along with the critical discussion on electrode designs for supercapacitors to meet commercial standards.
UNLABELLED: For cardiovascular research on rodents, small-animal PET has limitations because of the inherent spatial resolution of the system and because of cardiac motion. A factor analysis (FA) technique for extracting the blood input function and myocardial time-activity curve from dynamic small-animal PET images of the rodent heart has been implemented to overcome these limitations. METHODS: Six Sprague-Dawley rats and 6 BALB/c mice underwent dynamic imaging with 18F-FDG (n = 6) and 1-11C-ac
Small heterodimer partner (SHP; NR0B2) is an atypical orphan nuclear receptor and acts as a coregulator of various nuclear receptors. Herein, we examined a novel cross talk between SHP and a forkhead transcription factor HNF3 (hepatocyte nuclear factor 3/Foxa. Transient transfection assay demonstrated that SHP inhibited the transcriptional activity of all three isoforms of HNF3, HNF3alpha, beta, and gamma. In vivo and in vitro protein interaction studies showed that SHP physically interacted wit
Surgery and post-operative radiotherapy were effective for locoregional control. Lymphovascular invasion and perineural invasion were significant prognostic factors in patients with SDC.
The purpose of this methodological study was to develop a convolutional neural network (CNN), which is a recently developed deep-learning-based image recognition method, to determine corneal ulcer severity in dogs. The CNN model was trained with images for which corneal ulcer severity (normal, superficial, and deep) were previously classified by veterinary ophthalmologists' diagnostic evaluations of corneal photographs from patients who visited the Veterinary Medical Teaching Hospital (VMTH) at
The electrochemical nitrogen reduction reaction (ENRR) is considered an environmentally-friendly process for ammonia production under ambient conditions, compared to the conventional Haber-Bosch method. However, the electrochemical synthesis of ammonia suffers from poor selectivity and low efficiency owing to constrained catalytic activity and the competitive hydrogen evolution reaction (HER). Spinel-type solid materials have received considerable interest owing to their various applications in
Abstract Electrochemical nitrogen reduction reaction (NRR) is a sustainable alternative to the Haber‒Bosch process for ammonia (NH 3 ) production. However, the significant uphill energy in the multistep NRR pathway is a bottleneck for favorable serial reactions. To overcome this challenge, we designed a vanadium oxide/nitride (V 2 O 3 /VN) hybrid electrocatalyst in which V 2 O 3 and VN coexist coherently at the heterogeneous interface. Since single‐phase V 2 O 3 and VN exhibit different surface
OBJECTIVE: To evaluate the effectiveness of bovine freeze-dried amniotic membrane (FD-AM) (Amnisite-BA) in the surgical treatment of corneal ulceration in dogs. ANIMALS STUDIED: Eight normal Shih-tzu dogs. PROCEDURES: The corneas of 16 eyes were scored with an 8.0-mm trephine under general anesthetic and 100% ethanol was applied to remove a standardized button of corneal epithelium. The eyes were treated as described below and the corneas were evaluated 48 h later. The dogs were divided into fou
Regenerative medicine requires both tissue restoration and ease of compliance for clinical application. Considering this, sticky tissue sealants have been shown to have great potentials over surgical suturing and wound treatment. However, tissue sealants currently used pose challenges such as uncontrollable adhesion formation, mechanical mismatch, and lack of tissue restoration. A new sticky sealant based on gelatinized cornea-derived extracellular matrix (GelCodE) with a visible light-activatin
This study was performed to analyze risk factors for and treatment results of ulcerative keratitis. The mean age (±SD) of 32 dogs with ulcerative keratitis was 3.59 (±2.97) years and the most commonly affected breed was the Shih-tzu (50%). Keratoconjunctivitis sicca (31%) was the predominant cause of ulcerative keratitis. Superficial corneal ulcers (in 44% of animals) treated with medication alone required 5.1-13.4 days for healing and dogs recovered well, without complications. Deep corneal ulc
Various cosmetics having a single function are increasingly being used, but cosmetics having multifunctional activities remain limited. We aimed to develop a multifunctional cosmetic cream having antioxidant, anti-tyrosinase, anti-aging and antimicrobial activities. Antimicrobial activities were performed by disc-diffusion method. Cell toxicity and cell proliferations were evaluated in a 96-well plate with different cell lines such as HaCaT, RAW264.7, CCD-986Sk, B16F1, and B16F10. Mushroom tyros
To evaluate the potential utility of a self-expandable intratracheal nitinol stent with flared ends for the treatment of tracheal collapse in dogs, endotracheal stenting therapy was performed under fluoroscopic guidance in four dogs with severe tracheal collapse. During the 4 to 7 month followup, after stent implantation, clinical signs, including dyspnea and respiratory distress, dramatically improved in all dogs. The radiographs showed that the implanted stents improved the tracheal collapse,
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