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채준석 교수

Joonseok Chae

서울대학교 수의학과 · 의학

연구실 소개

채준석 교수의 연구실은 한국의 토착 병원성 병원체 및 출현·재출현 위협이 있는 감염병 원인체의 역학과 생물다양성을 중심으로 연구를 진행하고 있습니다. 주로 유전자 분석, 분자진단법, 그리고 토양·동물·기생충을 통한 병원체 유통 경로를 규명하는 데 초점을 맞추고 있으며, 특히 라이프스타일과 기후 변화가 영향을 미치는 감염병의 생태학적 기반을 탐구하고 있습니다. 특히 한국에서 발견되는 에릭리히아, 안플라즈마, 락토바실러스 등 병원성 세균과 바이러스의 분포 및 진화를 다루며, 동물과 기생충을 통해 인간과 가축에 영향을 미치는 병원체의 전파 메커니즘을 규명하고자 합니다.

병원체 생태학모든 기생충분자진단감염병 역학동물 병원체

연구 현황

논문 수
53
총 인용 수
339
최근 5년 논문
13
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
13총합
2018
2019
2020
2021
2022
5개년 연도별 피인용 수
40총합
20182019202020212022

주요 논문

15
1
논문|인용수 61·2013
Seasonal Distribution of Ticks in Four Habitats near the Demilitarized Zone, Gyeonggi-do (Province), Republic of Korea
Sung-Tae Chong, Heung-Chul Kim, 이인용, Thomas M. Kollars Jr., Alfredo R. Sancho, William J. Sames, 채준석, Terry A. Klein

This study describes the seasonal distribution of larvae, nymph, and adult life stages for 3 species of ixodid ticks collected by tick drag and sweep methods from various habitats in the Republic of Korea (ROK). Grasses less than 0.5 m in height, including herbaceous and crawling vegetation, and deciduous, conifer, and mixed forests with abundant leaf/needle litter were surveyed at United States (US) and ROK operated military training sites and privately owned lands near the demilitarized zone f

2
논문|인용수 47·2011
Ticks Collected from Selected Mammalian Hosts Surveyed in the Republic of Korea During 2008-2009
Heung Chul Kim, 한상훈, Sung Tae Chong, Terry A. Klein, 최창용, Hyun-Young Nam, 채희영, 이항, 고성진, 강준구, 채준석

A tick survey was conducted to determine the relative abundance and distribution of ticks associated with selected mammals in the Republic of Korea (ROK) during 2008-2009. A total of 918 ticks were collected from 76 mammals (6 families, 9 species) captured at 6 provinces and 3 Metropolitan Cities in ROK. Haemaphysalis longicornis (54.4%) was the most frequently collected tick, followed by Haemaphysalis flava (28.5%), Ixodes nipponensis (7.6%), Ixodes pomerantzevi (4.8%), Ixodes persulcatus (4.6%

3
논문|인용수 35·2010
Prevalence of tick-borne encephalitis virus in ticks from southern Korea
고성진, 강준구, Su Yeon Kim, Heung-Chul Kim, Terry A. Klein, Sung-Tae Chong, William J. Sames, Seok-Min Yun, Young-Ran Ju, 채준석

The prevalence of tick-borne encephalitis virus (TBEV) in southern Korea was determined by collecting ticks using tick drags. A total of 4,077 of 6,788 ticks collected were pooled (649pools) according to collection site, species, and developmental stage and assayed for TBEV. The TBEV protein E and NS5gene fragments were detected using RT-nested PCR in six pools of nymphs collected from Jeju Island (2,491 ticks). The minimum field detection rates for TBEV were 0.17% and 0.14% for Haemaphysalis lo

4
논문|인용수 24·2017
Identification of Tick Species Collected from Wild Boars and Habitats of Wild Boars and Domestic Pigs in the Republic of Korea
채정병, 강준구, 김형철, 정승태, 이인용, 신남식, 채준석

Tick is one of the most important arthropods in the transmission of vector-borne diseases. In this study, we investigated the abundance and species of ticks associated with swine and their habitats to assess the risk of spread of tick-borne diseases in host species, such as wild boars. Ticks were collected from 24 grazing or traditionally reared domestic pig farms and 8 habitats of wild boars in 8 provinces and 1 city in the Republic of Korea, by using the dragging and flagging methods. Ticks we

5
논문|인용수 23·2012
Evaluation of the effect of a 0.0584% hydrocortisone aceponate spray on clinical signs and skin barrier function in dogs with atopic dermatitis
Eui‐Hwa Nam, Seol-Hee Park, Ji-Young Jung, Seung-Hee Han, Hwa‐Young Youn, Jun-Seok Chae, Cheol‐Yong Hwang
SJR Q2Journal of Veterinary ScienceOA

The purpose of this study was to evaluate the effects of a topical spray containing 0.0584% hydrocortisone aceponate (HCA) on canine atopic dermatitis (CAD) and to evaluate the skin barrier function during the treatment of CAD. Twenty-one dogs that fulfilled the diagnostic criteria for CAD were included in this study. The HCA spray was applied once a day to the lesions of all dogs for 7 or 14 days. Clinical assessment was performed before (day 0) and after treatment (day 14), and clinical respon

DermatologyMedicine
6
논문|인용수 19·2013
Characterization and clinical application of mesenchymal stem cells from equine umbilical cord blood
강준구, 박상범, 서민수, 김형식, 채준석, 강경선
http://pdf.medrang.co.kr/JVS/014/Jvs014-03-18.pdf

Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic

7
논문|인용수 14·2018
Detection and Identification of Sarcocystis cruzi (Protozoa: Apicomplexa) by Molecular and Ultrastructural Studies in Naturally Infected Korean Cattle (Bos taurus coreanae) from Daejeon, Korea
최통일, 홍의주, 류시윤, 심철호, 채준석, 김현철, 박진호, 최경성, 유도현, 유재규, 박배근

To survey the prevalence of Sarcocystis infections, 210 heart samples were collected from Korean native cattle (Bos taurus coreanae) at an abattoir in Daejeon Metropolitan City, Republic of Korea. Sarcocysts were detected form 31 specimens (14.8%) and identified as Sarcocystis cruzi via transmission electron microscopy. The wall of S. cruzi has flattened protrusions that did not contain fibrils or microfilaments. The protrusions arose irregularly from the base, contained a fine granular substanc

8
논문|인용수 13·2013
Isolation and characterization of equine amniotic membrane-derived mesenchymal stem cells
서민수, 박상범, 김형식, 강준구, 채준석, 강경선
http://pdf.medrang.co.kr/JVS/014/Jvs014-02-06.pdf

Recent studies have shown that mesenchymal stem cells (MSCs) are able to differentiate into multi-lineage cells such as adipocytes, chondroblasts, and osteoblasts. Amniotic membrane from whole placenta is a good source of stem cells in humans. This membrane can potentially be used for wound healing and corneal surface reconstruction. Moreover, it can be easily obtained after delivery and is usually discarded as classified waste. In the present study, we successfully isolated and characterized eq

9
논문|인용수 13·2017
Hematological Changes Associated with Theileria orientalis Infection in Korean Indigenous Cattle
김수희, 유도현, 강성우, 채정병, 최경성, 김현철, 박배근, 채준석, 박진호

Tick-borne pathogens can cause serious problems in grazing cattle. However, little information is available on tick-mediated diseases in cattle grazing on mountains. Thus, this study aimed to understand the potential problems related to tick-borne diseases in grazing cattle through the investigation of prevalent tick-transmitted infections, and their associated hematological changes, in terms of season and grazing type in Korean indigenous cattle (=Hanwoo). Hanwoo cattle from 3 regions of the Re

10
논문|인용수 11·2018
Epidemiological Survey on Eimeria spp. Associated with Diarrhea in Pre-weaned Native Korean Calves
김현철, 최창영, 김수희, 채준석, 유도현, 박진호, 박배근, 최경성

Bovine coccidiosis is one of the most important parasitic diseases affecting calf productivity. Here, we investi- gated the prevalence of Eimeria spp. in pre-weaned native Korean calves and determined the correlation between diar- rhea and Eimeria spp. Fecal samples were collected from individual calves (288 normal and 191 diarrheic) in 6 different farms. Of the 479 samples, Eimeria oocysts were detected in 124 calves (25.9%). Five Eimeria spp. were identified; E. zu- ernii (18.8%) was the most

11
논문|인용수 11·2013
Characterization and Zoonotic Potential of Uropathogenic Escherichia coli Isolated from Dogs
남의화, 고성진, 채준석, 황철용

The aim of this study was to investigate the characteristics of canine uropathogenic Escherichia coli (UPEC) and the interaction between canine UPEC and human bladder epithelial cells. Ten E. coli isolates collected from dogs with cystitis were analyzed for antimicrobial resistance patterns, the presence of virulence factors, and biofilm formation. The ability of these isolates to induce cytotoxicity,invade human bladder epithelial cells, and stimulate an immune response was also determined. We

12
논문|인용수 9·2009
Genetic Identification and Phylogenetic Analysis of Anaplasma and Ehrlichia Species in Haemaphysalis longicornis Collected from Jeju Island, Korea
오재영, Bong-Chun Moon, 배보경, E-Hyun Shin, Young Hwan Ko, Young-Joo Kim, 박용호, 채준석

A total of 1,395 Haemaphysalis longicornis ticks collected from Jeju Island of Korea were examined by 16S rRNAgene-based nested PCR for the presence of infection with Anaplasma and Ehrlichia species. Template DNAs to detectthe tick-borne pathogens were prepared from a total 506 tick pools. Eight genera of Anaplasma and six Ehrlichia by16S rRNA gene PCR and sequencing analysis were identified. A. phagocytophilum was the most prevalent (27 [1.9%])by nested PCR, followed by A. bovis (5 [0.4%]), E.

13
논문|인용수 7·2017
관악산에서 참진드기 조사 및 중증열성혈소판감소증후군 바이러스 검출
채정병, 김태희, 정지호, 박윤지, 박진호, 최경성, 유도현, 박배근, 채준석
대한수의학회지

This study was performed to investigate the distribution of ticks and the rate of infection with severe feverwith thrombocytopenia syndrome (SFTS) virus in ticks collected at Mt. Gwanak and the Seoul National Universitycampus, Korea. Ticks (n = 273) were collected from May to October and included 76 Haemaphysalis longicornis (4adult females, 72 nymphs), 49 Haemaphysalis flava (9 adult females, 3 adult males, 37 nymphs), and 148 Haemaphysalisspp. larvae. SFTS virus detection was performed by usin

14
논문|인용수 6·2010
산삼 배양액 급여가 육계의 육질에 미치는 영향 연구
설재원, 박재홍, 채준석, 강형섭, 류경선, 강춘성, 박상열

본 연구에서는 산삼의 조직 배양 후 폐기되는 산삼 배양액을 육계에 음수를 통하여 다양한 농도로 급여한 후 계육의 일반 성분, 물리화학적인 성상 및 이화학적 성상 변화를 분석하여 산삼 배양액의 효능과 첨가제로서의 가능성을 규명하였다. 산삼 배양액을 급여한 육계 가슴육의 수분 함량, 조단백질과 조지방의 함량에 유의적인 차이는 보이지 않았지만 조회분의 함량은 산삼 배양액 32 mL/L 급여군이 다른 처리군에 비하여 유의적으로 증가하는 것을 볼 수 있었다. 또한, 산삼 배양액 급여군에서 육즙 손실, 조리 감량, 전단력과 저장성은 감소되는 경향을 보이나 유의적인 차이는 보이지 않았지만 산삼 배양액 급여군의 가슴육 pH는 유의성 있게 감소하였다. 이러한 결과는 산삼 배양액의 급여에 의해 육제품에서 미생물의 번식을 억제하고 보존이나 내구성을 강화시키거나, 육계의 골격 형성과 육질 내 삼투압이나 항상성 유지에 도움을 줄 것으로 사료된다.

15
논문|인용수 5·2005
Prevalence of Brucella antibodies in sera of cows in Bangladesh
채준석, Kazi M.R.Amin, M.Bahanur Rahman, M.Siddiqur Rahman, Jae-cheol Han, Jin-Ho Park

The study was carried out to investigate the prevalence of Brucella antibodies in sera of 120 cows in Bangladesh Agricultural University Dairy Farm and adjacent villages, Bangladesh. The epidemiological history and blood was collected from the cows. The serum samples were subjected to Rose Bengal Test (RBT) and plate agglutination test (PAT) for initial screening of Brucella antibodies and the positive sera samples were then subjected to tube agglutination test (TAT) for further confirmation. Th

대표 연구 분야

DermatologyParasitologyBiochemistryUrologyOncologyPharmacology

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