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이준호 교수

Jun Ho Lee

한양대학교 외과 · 의학

연구실 소개

이준호 교수의 연구실은 위암의 병행성 종양, 조기 위암의 임상적 특성 및 예후 인자에 대한 심층적인 연구를 중심으로 하며, 특히 CCR4, SOX 그룹 F 유전자, 혈장 피브리노겐 수치 등 종양 미세환경과 관련된 생물학적 마커들이 위암 진행과 예후에 미치는 영향을 규명하고자 합니다. 또한, 혈관 생성 및 림프관 형성과 관련된 유전자 기전과 호르몬 영향 등 종양 생물학의 핵심 메커니즘을 밝히는 데 초점을 맞추고 있습니다. 이는 조기 진단 및 개인화된 치료 전략 개발에 기여할 임상의학적 통찰을 제공합니다.

위암 예후 마커CCR4SOX 그룹 F혈관 생성피브리노겐 수치

연구 현황

논문 수
95
총 인용 수
1,490
최근 5년 논문
16
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
16총합
2021
2022
2024
2025
2026
5개년 연도별 피인용 수
48총합
20212022202420252026

주요 논문

15
1
논문|인용수 102·2006
Gastric cancer patients at high-risk of having synchronous cancer
Jun Ho Lee
SJR Q1World Journal of GastroenterologyOA

Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric cancer.

EpidemiologyMedicine
2
논문|인용수 45·2009
The Chemokine Receptor CCR4 is Expressed and Associated With a Poor Prognosis in Patients With Gastric Cancer
Jun Ho Lee, Young‐Suk Cho, Ji Young Lee, Myeong‐Cherl Kook, Jong-Whan Park, Byung‐Ho Nam, Jae-Moon Bae
SJR Q1Annals of Surgery

These results suggest that CCR4 and its ligands were associated with increased tumor recurrence and impaired overall survival in patients with gastric cancer.

OncologyMedicine
3
논문|인용수 39·2016
Identification of Recurrence—Predictive Indicators in Stage I Colorectal Cancer
Jun Ho Lee, Jong Lyul Lee, In Ja Park, Seok‐Byung Lim, Chang Sik Yu, Jin Cheon Kim
SJR Q1World Journal of Surgery

BACKGROUND: Patients with stage I colorectal cancer (CRC) rarely experience recurrences; therefore, few risk factors for recurrence are known. This study was designed to evaluate oncologic outcomes of patients with stage I CRC and to identify risk factors for recurrence after curative surgery. METHODS: A retrospective cohort of 860 patients from a single institution who underwent curative surgery for stage I CRC between July 1995 and June 2010 was enrolled. Patients who were diagnosed with hered

OncologyMedicine
4
논문|인용수 36·2017
A Research of Pyogenic Granuloma Genesis Factor With Immunohistochemical Analysis
Si‐Hyun Park, Jun Ho Lee, Min Sung Tak, Hyun Ju Lee, Hwan Jun Choi
SJR Q2Journal of Craniofacial Surgery

Pyogenic granuloma (PG) is a type of vascular tumor for which the growth mechanism is poorly understood. Estrogen and progesterone may influence vascular malformations by increasing neovascularization in the lesions. Pregnancy tumor is a term for PG that occurs on the gingival mucosa of pregnant women in response to local irritation or injury. The etiology and pathogenesis of this phenomenon are not fully understood. Hormonal imbalance has been hypothesized to be responsible for the development

SurgeryMedicine
5
논문|인용수 35·2005
Preoperative plasma fibrinogen levels in gastric cancer patients correlate with extent of tumor.
Jun Ho Lee, Keun Won Ryu, Sung Hoon Kim, Jae Moon Bae
PubMed

BACKGROUND/AIMS: The aim of the present study was to investigate the relationship between the preoperative plasma fibrinogen level and the extent of tumor involvement in gastric cancer patients. METHODOLOGY: Preoperative plasma fibrinogen levels of 354 patients who underwent gastric cancer surgery were quantified using an immunoassay. The relationships between the plasma fibrinogen level and other prognostic variables (tumor size, macroscopic and histological type, depth of tumor invasion, prese

OncologyMedicine
6
논문|인용수 31·2011
The lymphangiogenic factor SOX 18: A key indicator to stage gastric tumor progression
Bang Wool Eom, Min Jung Jo, Myeong‐Cherl Kook, Keun Won Ryu, Il Ju Choi, Byung‐Ho Nam, Young‐Woo Kim, Jun Ho Lee
SJR Q1International Journal of Cancer

SOX group F genes are important regulators of angiogenesis and lymphangiogenesis. The aim of the present study was to examine the relationships between Sox group F expression and clinicopathological factors in gastric cancer. Three hundred and fifteen gastric cancer tissues and the corresponding normal gastric tissue were obtained from the tumor bank at the National Cancer Center, Korea. SOX group F mRNA levels in these tissues were evaluated by reverse transcriptase polymerase chain reaction (R

ImmunologyImmunology and Microbiology
7
논문|인용수 30·2008
Surgical Complications of Epilepsy Surgery Procedures : Experience of 179 Procedures in a Single Institute
Jun Ho Lee, Yong Soon Hwang, Jun Jae Shin, Tae Hong Kim, Hyung Shik Shin, Sang Keun Park
SJR Q2Journal of Korean Neurosurgical SocietyOA

OBJECTIVE: There are a few reports on the complications of surgery for epilepsy. We surveyed our data to present complications of epilepsy surgeries from the neurosurgeon's point of view and compare our results with other previous reports. METHODS: A total of 179 surgical procedures for intractable epilepsy (41 diagnostic, 138 therapeutic) were performed in 92 consecutive patients (10 adults, 82 children) during the last 9.2 years (February. 1997-April. 2006). Their medical records and radiologi

Psychiatry and Mental healthMedicine
8
논문|인용수 24·2020
Loss of ASXL1 expression is associated with lymph node metastasis in colorectal cancer
Jun Ho Lee, JunH Lee, Ju‐Hee Lee, ByungK Ahn, SeungS Paik, Hyunsung Kim
SJR Q3Indian Journal of Pathology and MicrobiologyOA

ASXL1 might act as a tumor suppressor in CRC. The loss of ASXL1 expression might be associated with lymph node metastasis and lymphatic invasion in CRC.

Pathology and Forensic MedicineMedicine
9
논문|인용수 21·2016
Factors affecting the postoperative morbidity and survival of patients with liver cirrhosis following colorectal cancer surgery
Jun Ho Lee, Chang Sik Yu, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok‐Byung Lim, Jin Cheon Kim
SJR Q2International Journal of Colorectal Disease
HepatologyMedicine
10
논문|인용수 15·2020
Incidence and Mortality Rates of Thoracic Aortic Dissection in Korea – Inferred from the Nationwide Health Insurance Claims
이준호, 조용일, 조양현, 강형구, 임태호, 장효준, 노선균, 김혁
https://www.jkms.org/search.php?where=aview&id=10.3346/jkms.2020.35.e360&code=0063JKMS&vmode=FULL

Background: Aortic dissection (AD) is one of the most catastrophic diseases and is associated with high morbidity and mortality. The aim of this study is to investigate the hospital incidence and mortality rates of thoracic AD in Korea using a nationwide database. Methods: We conducted a nationwide population-based study using the health claims data of the National Health Insurance Service in Korea. From 2005 to 2016, adult patients newly diagnosed with AD were included. All patients were divide

11
논문|인용수 14·2021
Mechanical bowel preparation combined with oral antibiotics in colorectal cancer surgery: a nationwide population-based study
Jun Ho Lee, Byung Kyu Ahn, Jiin Ryu, Kang Hong Lee
SJR Q2International Journal of Colorectal Disease
SurgeryMedicine
12
리뷰|인용수 12·2021
Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis
Jun Ho Lee, Byung Kyu Ahn, Kang Hong Lee
SJR Q2International Journal of Colorectal Disease
SurgeryMedicine
13
논문|인용수 12·2020
Prognostic value of B-cell linker protein in colorectal cancer
Jun Ho Lee, Ju‐Hee Lee, Byung Kyu Ahn, Seung Sam Paik, Kang Hong Lee
Pathology - Research and Practice
GeneticsMedicine
14
논문|인용수 11·2014
Quality and Antioxidant Properties of Pound Cakes Supplemented with Flaxseed Powder
Ha‐Sook Chung, Jeong Ah Lim, Jun Ho Lee
SJR Q3Journal of the Korean Society of Food Science and Nutrition

아마씨 분말의 첨가량을 0~8%로 달리하여 파운드케이크를 제조한 후 물리ㆍ화학적 품질, 항산화 활성 및 소비자 기호도를 조사하였다. 케이크의 굽기 손실률은 아마씨 분말의 첨가량이 증가함에 따라 유의적으로 증가하였으며(P<0.05), 수분함량, 부피, 높이 및 경도는 아마씨 분말의 함량이 증가함에 따라 유의적으로 감소하였다(P<0.05). 한편 명도(L<SUP>*</SUP>)와 황색도(b<SUP>*</SUP>)는 황갈색인 아마씨 분말의 첨가량이 증가함에 따라 유의적으로 감소하였으며(P<0.05), 적색도(a<SUP>*</SUP>)는 유의적으로 증가하였다(P<0.05). 항산화 활성을 나타내는 DPPH와 ABTS radical 소거능은 유의적 차이를 나타내며 증가하였으며(P<0.05), 두 지표 사이의 상관관계가 매우 높은 것으로 나타났다. 소비자 기호도 검사 결과 색을 제외한 모든 평가항목에서 아마씨 분말 2% 첨가군이 대조군에 비해 높게 평가되었으며, 아마씨 분말의 첨가량이 증가함에

Pathology and Forensic MedicineMedicine
15
letter|인용수 8·2017
Identification of Recurrence‐Predictive Indicators in Stage I Colorectal Cancer: Reply
Jun Ho Lee, Jong Lyul Lee, Jin Cheon Kim
SJR Q1World Journal of Surgery
OncologyMedicine

대표 연구 분야

OncologySurgeryPsychiatry and Mental healthPulmonary and Respiratory MedicinePathology and Forensic MedicineAccounting

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