이정헌 교수
Jung-Hoon Lee
성균관대학교 신소재공학과 · 재료과학
연구실 소개
이정헌 교수의 연구실은 나노소재 및 생체적합성 전자소재를 기반으로 한 스마트 헬스케어 기기 개발에 주력하고 있습니다. 특히 스마트 콘택트 렌즈, 나노입자 기반 생체 센서, 그리고 고성능 태양전지에 응용 가능한 나노구조 재료의 설계와 분석에 초점을 맞추고 있습니다. 유전자 지능형 센서, 전자현미경 기반의 대량 나노입자 분석 기술, 그리고 생체재료의 물리화학적 특성 분석을 통해 임상적 응용 가능성을 높이고자 합니다.
연구 현황
연구 성과 추이
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주요 논문
15Recent advances in wearable electronics combined with wireless communications are essential to the realization of medical applications through health monitoring technologies. For example, a smart contact lens, which is capable of monitoring the physiological information of the eye and tear fluid, could provide real-time, noninvasive medical diagnostics. However, previous reports concerning the smart contact lens have indicated that opaque and brittle components have been used to enable the opera
Colorimetric uranium sensors based on uranyl (UO2(2+)) specific DNAzyme and gold nanoparticles (AuNP) have been developed and demonstrated using both labeled and label-free methods. In the labeled method, a uranyl-specific DNAzyme was attached to AuNP, forming purple aggregates. The presence of uranyl induced disassembly of the DNAzyme functionalized AuNP aggregates, resulting in red individual AuNPs. Once assembled, such a "turn-on" sensor is highly stable, works in a single step at room temper
Although transmission electron microscopy (TEM) may be one of the most efficient techniques available for studying the morphological characteristics of nanoparticles, analyzing them quantitatively in a statistical manner is exceedingly difficult. Herein, we report a method for mass-throughput analysis of the morphologies of nanoparticles by applying a genetic algorithm to an image analysis technique. The proposed method enables the analysis of over 150,000 nanoparticles with a high precision of
MgO ultrathin nanolayers are able to efficiently retard charge recombination in perovskite solar cells.
Going for double gold: Precise control of the positions of and distances between gold nanoparticles (AuNP; gold spheres in picture) is achieved by linking the AuNPs to phosphorothioate-modified DNA (green and red helices) with a bifunctional fastener. The distance between AuNPs is controlled simply by changing the position of the modifications on the DNA template.
PURPOSE: The physicochemical properties of a xenograft are very important because they strongly influence the bone regeneration capabilities of the graft material. Even though porcine xenografts have many advantages, only a few porcine xenografts are commercially available, and most of their physicochemical characteristics have yet to be reported. Thus, in this work we aimed to investigate the physicochemical characteristics of a porcine bone grafting material and compare them with those of 2 co
Colloidal nanosheets of nickel-manganese layered double hydroxides (LDHs) have been synthesized in high yields through a facile reverse micelle method with xylene as an oil phase and oleylamine as a surfactant. Electron microscopy studies of the product revealed the formation of colloidal nanoplatelets with sizes of 50-150 nm, and X-ray diffraction, energy dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy studies showed that the Ni-Mn LDH nanosheets had a hydrotalcite-like stru
The development of eco-friendly flame retardants is crucial due to the hazardous properties of most conventional flame retardants. Herein, adenosine triphosphate (ATP) is reported to be a highly efficient "all-in-one" green flame retardant as it consists of three essential groups, which lead to the formation of char with extreme intumescence, namely, three phosphate groups, providing an acid source; one ribose sugar, working as a char source; and one adenine, acting as a blowing agent. Polyureth
BACKGROUND: A considerable number of studies has been carried out to develop alloplastic bone graft materials such as hydroxyapatite (HAP) that mimic the hierarchical structure of natural bones with multiple levels of pores: macro-, micro-, and nanopores. Although nanopores are known to play many essential roles in natural bones, only a few studies have focused on HAPs containing them; none of those studies investigated the functions of nanopores in biological systems. METHOD: We developed a sim
Gold nanoparticles (AuNPs) are useful nanomaterials as transducers for colorimetric sensors because of their high extinction coefficient and ability to change color depending on aggregation status. Therefore, over the past few decades, AuNP-based colorimetric sensors have been widely applied in several environmental and biological applications, including the detection of water pollutants. According to various studies, water pollutants are classified into heavy metals or cationic metal ions, toxi
Controlled alignment of streptavidin (STV), myoglobin, and nanoparticles with nanometer resolution has been achieved via backbone-modified phosphorothioate DNA and biotin- and maleimide-containing bifunctional linkers. Introducing triplet biotin modifications in three adjacent PSs significantly increased the STV conjugation yield. By placing phosphorothioate modifications at multiple positions of a double stranded DNA template, monomer, dimer, and trimer STV-DNA assemblies were formed with the S
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