김기동 교수
K D Kim
서울대학교 산부인과 · 의학
연구실 소개
김기동 교수의 연구실은 주로 산모 및 여성암의 발생 및 예후에 영향을 미치는 임상적·분자적 요인을 규명하는 데 초점을 맞추고 있습니다. 특히 자궁경부암의 전이 양상, 신경주위침유(Perineural invasion)와 같은 새로운 예후 인자, 그리고 난소암 치료에서의 내성 문제 해결을 위한 천연물질의 약리적 효과를 중심으로 연구를 진행하고 있습니다. 또한 의료기록 데이터 기반의 과정 분석 기법을 활용한 의료 프로세스 최적화 연구도 함께 수행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The aim of this review is to examine the current status of gynecological cancer in China focusing on epidemiological data. Epidemiological data on gynecological cancer in China is sparse. Therefore, most of the data were estimated via extrapolation based on a few available datasets. Cervical cancer is relatively rare and the incidence and mortality rate are largely decreasing. However, in young women, the incidence and mortality rates are increasing. The overall and age-specific incidence rates
OBJECTIVE: THE OBJECTIVES OF THIS STUDY WERE TWOFOLD: to verify whether the type of metastasis (lymphatic vs. hematogenous) is a prognostic factor, and to identify molecular markers associated with survival in patients with disseminated cervical cancer. METHODS: Between April 1997 and May 2008, 30 patients with disseminated cervical cancer who had supraclavicular lymph node (N=13) or hematogenous metastases (N=17) were initially treated at our institute. We reviewed medical records to extract cl
Perineural invasion (PNI) has attracted attention as a new prognostic factor for cancer. We aimed to investigate the prognostic value of PNI in patients with cervical cancer. Clinical data of 185 patients with early-stage cervical cancer (stages IA2-IIA2) who underwent radical hysterectomy and pelvic lymphadenectomy between 2003 and 2011 were investigated. PNI was detected in 7% (13 of 18 cases) of patients. Moreover, 92% (12 of 13 cases) of patients with PNI received radiation therapy or concur
BACKGROUND AND OBJECTIVE: Recently, Electronic Health Records (EHR) are increasingly being converted to Common Data Models (CDMs), a database schema designed to provide standardized vocabularies to facilitate collaborative observational research. To date, however, rare attempts exist to leverage CDM data for healthcare process mining, a technique to derive process-related knowledge (e.g., process model) from event logs. This paper presents a method to extract, construct, and analyze event logs f
Abstract Background Ovarian cancer therapy generally involves systemic chemotherapy with anticancer drugs; however, chemotherapy with a platinum-based drug has often been shown to cause adverse reactions and drug resistance in ovarian cancer patients. Evodia rutaecarpa (ER) reportedly shows anticancer activity against various types of cancer cells. However, the effects of ER have not yet been fully uncovered in ovarian cancer. Methods In the present study, we investigated the anticancer effects
In this work the gas evolution behavior and the fining ability of the alkali‐free alkaline earth aluminoborosilicate glass batches doped with As 2 O 5 or SnO 2 were examined, and the redox behavior of As and Sn ion in the corresponding fined melts was investigated by square wave voltammetry. The evolved gas analysis showed a distinct difference at begin temperature of O 2 emission and in evolved O 2 volume between glass batches doped with As 2 O 5 and SnO 2 . One peak due to reduction of As 5+ t
In this review, we summarized nine major clinical advances in gynecology which occurred in 2009. For cervical cancer, the role of human papillomavirus (HPV) test as a screening test, the efficacy of HPV vaccine for middle-aged women, randomized controlled trial (RCT) regarding concurrent chemoradiation using gemcitabine plus cisplatin, and the efficacy of pazopanib for metastatic or recurrent disease were chosen. For endometrial cancer, the necessity of systematic pelvic lymphadenectomy in early
PURPOSE: To investigate whether the use of an activity tracker with feedback increases physical activity and is safe in patients who underwent a midline laparotomy for gynecologic disorders. METHODS: Patients who were planned to undergo a midline laparotomy for gynecologic diseases wore an activity tracker at baseline and from postoperative days 1-6. Patients in the experimental arm could monitor their step counts and were encouraged to achieve the individualized step-count goal daily. In contra
This study aimed to determine the factors influencing patients' choice of physician at the first visit through database analysis of a tertiary hospital in South Korea. We collected data on the first treatments performed by physicians who had treated patients for at least 3 consecutive years over 10 years (from 2003 to 2012) from the database of Seoul National University's affiliated tertiary hospital. Ultimately, we obtained data on 524,012 first treatments of 319,004 patients performed by 115 p
The device performance of nanoscale fin field-effect transistor (FinFET) was investigated by numerically solving coupled Poisson-Schrödinger equations in a self-consistent manner. The number of fins was varied in order to optimize the current driving capability of FinFET. The simulation results were compared with the experimental results in order to verify the validity of the proposed quantum mechanical approach. Device optimization was theoretically performed in order to suppress the short-chan
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